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Glycan Syntheses |
JCGG ID |
JCGG-RAC0001207 | ||||
Submitter |
The Noguchi Institute | ||||
Reaction ID |
R-0000-001213
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Regist Date |
2012/06/21 16:45:14 | ||||
| REACTANT | |||||
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Mol |
1 equiv. | ||||
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Reactant Type |
NH4HCO3 | ||||
Mol |
6532.8 + 3098.4 + 5180.3 equiv. | ||||
| PRODUCT | |||||
MOLECULE ID |
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Yield |
25%(at least) | ||||
| REACTION DETAIL | |||||
Reaction Time |
30 hours | ||||
Reaction Temp |
40 degree C | ||||
Solvent |
H2O | ||||
Comment |
NH4HCO3 was added three times. (0 hour, 2 hours, and 8.5 hours) | ||||
| COMMENT | |||||
| Keywords: prostate specific antigen, PSA, N-linked glycan, peptide backbone, antibody, cancer, amino acid, keyhole limpet hemocyanin, KLH | |||||
| REFERENCE | |||||
Reference Id |
REF-0000-000061 | ||||
Issn |
Electronic | ||||
Doi |
10.1021/ja8028137 | ||||
PubMed ID |
18798614 | ||||
Journal Name |
Journal of the American Chemical Society. (2008) 130 (41): 13598-607. | ||||
Article Title |
Toward a prostate specific antigen-based prostate cancer diagnostic assay: preparation of keyhole limpet hemocyanin-conjugated normal and transformed prostate specific antigen fragments. | ||||
Author |
Vadim Y, Dudkin; Justin S, Miller; Anna S, Dudkina; Christophe, Antczak; David A, Scheinberg; Samuel J, Danishefsky | ||||
Affiliation |
Laboratory for Bioorganic Chemistry, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, New York 10065, USA. | ||||
Reference Id |
REF-0000-000062 | ||||
Source |
J. AM. CHEM. SOC. 2008, 130, 13598-13607 | ||||
Doi |
10.1021/ja8028137 | ||||
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)
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