JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
JCGG-RAC0001194
Submitter
The Noguchi Institute
Reaction ID
R-0000-001200
Regist Date
2012/06/21 16:44:35
REACTANT
MOLECULE ID
JCGG-COM0001361 (Reaction Tree)
MOLECULE ID
JCGG-COM0000979
Reactant Type
pyridine
MOLECULE ID
JCGG-COM0000392
Reactant Type
BzCl
MOLECULE ID
JCGG-COM0000500
Reactant Type
DMAP
PRODUCT
MOLECULE ID
JCGG-COM0001299 (Reaction Tree)
Yield
98%
REACTION DETAIL
Reaction Time
26 hours
Reaction Temp
room temp
Solvent
CH2Cl2
COMMENT
Keywords: prostate specific antigen, PSA, N-linked glycan, peptide backbone, antibody, cancer, amino acid, keyhole limpet hemocyanin, KLH
REFERENCE
Reference Id
REF-0000-000061
Issn
Electronic
Doi
10.1021/ja8028137
PubMed ID
18798614
Journal Name
Journal of the American Chemical Society. (2008) 130 (41): 13598-607.
Article Title
Toward a prostate specific antigen-based prostate cancer diagnostic assay: preparation of keyhole limpet hemocyanin-conjugated normal and transformed prostate specific antigen fragments.
Author
Vadim Y, Dudkin; Justin S, Miller; Anna S, Dudkina; Christophe, Antczak; David A, Scheinberg; Samuel J, Danishefsky
Affiliation
Laboratory for Bioorganic Chemistry, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, New York 10065, USA.
Reference Id
REF-0000-000062
Source
J. AM. CHEM. SOC. 2008, 130, 13598-13607
Doi
10.1021/ja8028137

©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)