JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
 JCGG-RAC0001175
Submitter
 The Noguchi Institute
Reaction ID
 R-0000-001175
Regist Date
 2012/06/21 16:43:12
REACTANT
MOLECULE ID
 JCGG-COM0001332 (Reaction Tree)
Skeleton
JCGG-STR031569
Mol
 0.039 mmol
MOLECULE ID
 JCGG-COM0000029
Reactant Type
 Me2P(S)Cl
Mol
 0.039 mmol
MOLECULE ID
 JCGG-COM0000426
Reactant Type
 DIEA
Mol
 0.039 mmol
MOLECULE ID
 JCGG-COM0000427 (Reaction Tree)
Mol
 0.040 mmol
PRODUCT
MOLECULE ID
 JCGG-COM0001335 (Reaction Tree)
Yield
 63%(at least)
REACTION DETAIL
Reaction Time
 40 minutes, 24 hours
Reaction Temp
 NOT specified, NOT specified
Solvent
 DMF, DMF
Comment
 1) 8+Me2P(S)Cl, DIEA, 2) +12
COMMENT
Keywords: cyclodextrin, drug delivery system, drug carrier, stacking effect, arbutin, doxorubicin
The DOI could not be found.
There are two phases in this reaction.
REFERENCE
Reference Id
 REF-0000-000059
Issn
 Print
PubMed ID
 18473917
Journal Name
 Medicinal chemistry (Shāriqah (United Arab Emirates)). (2008) 4 (3): 244-55.
Article Title
 Beta-cyclodextrin conjugates with glucose moieties designed as drug carriers: their syntheses, evaluations using concanavalin A and doxorubicin, and structural analyses by NMR spectroscopy.
Author
 Yoshiki, Oda; Natsumi, Kobayashi; Takashi, Yamanoi; Kaname, Katsuraya; Keiko, Takahashi; Kenjiro, Hattori
Affiliation
 The Noguchi Institute, 1-8-1 Kaga, Itabashi-ku, Tokyo 173-0003, Japan.
Reference Id
 REF-0000-000060
Source
 Medicinal Chemistry, 2008, 4, 244-255
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)