|
Glycan Syntheses |
JCGG ID |
JCGG-RAC0001170 | |||||||
Submitter |
The Noguchi Institute | |||||||
Reaction ID |
R-0000-001170
|
|||||||
Regist Date |
2012/06/21 16:42:58 | |||||||
| REACTANT | ||||||||
|
|
|
|
||||||
Mol |
6.18 mmol | |||||||
|
|
|
|||||||
Reactant Type |
NaH | |||||||
Mol |
103 mmol | |||||||
|
|
|
|||||||
Reactant Type |
BnBr | |||||||
Mol |
74.3 mmol | |||||||
| PRODUCT | ||||||||
MOLECULE ID |
|
|
|
|||||
Yield |
93% | |||||||
| REACTION DETAIL | ||||||||
Reaction Time |
20 minutes, 12 hours | |||||||
Reaction Temp |
0 degree C, room temp | |||||||
Solvent |
DMF, DMF | |||||||
Comment |
1) 5+NaH, 2) +BnBr | |||||||
| COMMENT | ||||||||
| Keywords: cyclodextrin, drug delivery system, drug carrier, stacking effect, arbutin, doxorubicin | ||||||||
| The DOI could not be found. | ||||||||
| There are two phases in this reaction. | ||||||||
| REFERENCE | ||||||||
Reference Id |
REF-0000-000059 | |||||||
Issn |
||||||||
PubMed ID |
18473917 | |||||||
Journal Name |
Medicinal chemistry (Shāriqah (United Arab Emirates)). (2008) 4 (3): 244-55. | |||||||
Article Title |
Beta-cyclodextrin conjugates with glucose moieties designed as drug carriers: their syntheses, evaluations using concanavalin A and doxorubicin, and structural analyses by NMR spectroscopy. | |||||||
Author |
Yoshiki, Oda; Natsumi, Kobayashi; Takashi, Yamanoi; Kaname, Katsuraya; Keiko, Takahashi; Kenjiro, Hattori | |||||||
Affiliation |
The Noguchi Institute, 1-8-1 Kaga, Itabashi-ku, Tokyo 173-0003, Japan. | |||||||
Reference Id |
REF-0000-000060 | |||||||
Source |
Medicinal Chemistry, 2008, 4, 244-255 | |||||||
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)
|
