JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
JCGG-RAC0001169
Submitter
The Noguchi Institute
Reaction ID
R-0000-001169
Regist Date
2012/06/21 16:42:55
REACTANT
MOLECULE ID
JCGG-COM0001328 (Reaction Tree)
Skeleton
JCGG-STR031569
Mol
18.4 mmol
MOLECULE ID
JCGG-COM0000418
Reactant Type
NaOH (0.5 M in H2O)
Mol
1.85 mmol
MOLECULE ID
JCGG-COM0000419
Reactant Type
AllylBr
Mol
23.1 mmol
PRODUCT
MOLECULE ID
JCGG-COM0001329 (Reaction Tree)
Skeleton
JCGG-STR031569
Yield
99%
REACTION DETAIL
Reaction Time
20 minutes, 19 hours
Reaction Temp
room temp, NOT specified
Solvent
H2O, DMF
Comment
1) 1+NaOH, 2) +AllylBr
COMMENT
Keywords: cyclodextrin, drug delivery system, drug carrier, stacking effect, arbutin, doxorubicin
The DOI could not be found.
There are two phases in this reaction.
REFERENCE
Reference Id
REF-0000-000059
Issn
Print
PubMed ID
18473917
Journal Name
Medicinal chemistry (Shāriqah (United Arab Emirates)). (2008) 4 (3): 244-55.
Article Title
Beta-cyclodextrin conjugates with glucose moieties designed as drug carriers: their syntheses, evaluations using concanavalin A and doxorubicin, and structural analyses by NMR spectroscopy.
Author
Yoshiki, Oda; Natsumi, Kobayashi; Takashi, Yamanoi; Kaname, Katsuraya; Keiko, Takahashi; Kenjiro, Hattori
Affiliation
The Noguchi Institute, 1-8-1 Kaga, Itabashi-ku, Tokyo 173-0003, Japan.
Reference Id
REF-0000-000060
Source
Medicinal Chemistry, 2008, 4, 244-255

©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)