JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
JCGG-RAC0001161
Submitter
The Noguchi Institute
Reaction ID
R-0000-001139
Regist Date
2012/06/21 16:41:08
REACTANT
MOLECULE ID
JCGG-COM0001285 (Reaction Tree)
Mol
12.2 micro mole
MOLECULE ID
JCGG-COM0001286
Reactant Type
NH4HCO3
Mol
79.7 + 37.8 + 63.2 mmol
PRODUCT
MOLECULE ID
JCGG-COM0001287 (Reaction Tree)
Yield
61%(at least)
REACTION DETAIL
Reaction Time
30 hours
Reaction Temp
40 degree C
Solvent
H2O
Comment
NH4HCO3 was added three times. (0 hour, 2 hours, and 8.5 hours)
COMMENT
Keywords: cancer, prostate gland, prostatic epithelium, prostate specific antigen, PSA, amino acid residues
REFERENCE
Reference Id
REF-0000-000054
Issn
Print
Doi
10.1021/ja037988s
PubMed ID
14733546
Journal Name
Journal of the American Chemical Society. (2004) 126 (3): 736-8.
Article Title
Chemical synthesis of normal and transformed PSA glycopeptides.
Author
Vadim Y, Dudkin; Justin S, Miller; Samuel J, Danishefsky
Affiliation
Laboratory for Bioorganic Chemistry, The Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, New York 10021, USA.
Reference Id
REF-0000-000055
Source
J. Am. Chem. Soc., 2004, 126 (3), pp 736-738
Doi
10.1021/ja037988s

©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)