JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
JCGG-RAC0001135
Submitter
The Noguchi Institute
Reaction ID
R-0000-001137
Regist Date
2012/06/21 16:41:00
REACTANT
MOLECULE ID
JCGG-COM0001282 (Reaction Tree)
Mol
29.8 micro mole
MOLECULE ID
JCGG-COM0000491
Reactant Type
AcOH (1.0 M in THF)
Mol
2.0 mmol
MOLECULE ID
JCGG-COM0001022
Reactant Type
TBAF (1.0 M in THF)
Mol
0.8 mmol
PRODUCT
MOLECULE ID
JCGG-COM0001283 (Reaction Tree)
Yield
76%
REACTION DETAIL
Reaction Time
21 hours
Reaction Temp
ambient temperature
Solvent
THF
COMMENT
Keywords: cancer, prostate gland, prostatic epithelium, prostate specific antigen, PSA, amino acid residues
REFERENCE
Reference Id
REF-0000-000054
Issn
Print
Doi
10.1021/ja037988s
PubMed ID
14733546
Journal Name
Journal of the American Chemical Society. (2004) 126 (3): 736-8.
Article Title
Chemical synthesis of normal and transformed PSA glycopeptides.
Author
Vadim Y, Dudkin; Justin S, Miller; Samuel J, Danishefsky
Affiliation
Laboratory for Bioorganic Chemistry, The Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, New York 10021, USA.
Reference Id
REF-0000-000055
Source
J. Am. Chem. Soc., 2004, 126 (3), pp 736-738
Doi
10.1021/ja037988s

©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)