JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
 JCGG-RAC0000901
Submitter
 The Noguchi Institute
Reaction ID
 R-0000-000901
Regist Date
 2012/06/21 16:29:03
REACTANT
MOLECULE ID
 JCGG-COM0001019 (Reaction Tree)
Skeleton
JCGG-STR025660
Reactant Type
 pentenyl glycoside
Mol
 0.521 mmol
MOLECULE ID
 JCGG-COM0001020 (Reaction Tree)
Reactant Type
 acceptor
Mol
 1.04 mmol
MOLECULE ID
 JCGG-COM0000129
Reactant Type
 NIS
Mol
 1.30 mmol
MOLECULE ID
 JCGG-COM0000111
Reactant Type
 TfOH
Mol
 0.521 mmol
PRODUCT
MOLECULE ID
 JCGG-COM0001021 (Reaction Tree)
Yield
 69%
REACTION DETAIL
Reaction Time
 12 hours
Reaction Temp
 room temp
Solvent
 CH2Cl2
Comment
 4A MS was included in the solvent.
3, 4, and 4A MS were mixed and stirred for 30 minutes at room temperature before the reaction.
The reactants were mixed at 0 degree in Celsius, and gradually raised to room temperature within the reaction time.
COMMENT
The PMID could not be found.
ATTENTION: There is a typo in the scheme. (TFA should be TfOH)
REFERENCE
Reference Id
 REF-0000-000041
Source
 J. Am. Chem. Soc. 1999, 121, 10636-10637
Doi
 10.1021/ja992309s
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)