JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
 JCGG-RAC0000865
Submitter
 The Noguchi Institute
Reaction ID
 R-0000-000865
Regist Date
 2012/06/21 16:27:19
REACTANT
MOLECULE ID
 JCGG-COM0000999
Reactant Type
 dissolved in 50% TFA in CH2Cl2
Mol
 30 micro mole
MOLECULE ID
 JCGG-COM0000047
Reactant Type
 Et3N
Volume
 0.5 mL
MOLECULE ID
 JCGG-COM0000578
Reactant Type
 HOBt
Mol
 40 micro mole
MOLECULE ID
 JCGG-COM0000984 (Reaction Tree)
Skeleton
JCGG-STR032134
Mol
 40 micro mole
MOLECULE ID
 JCGG-COM0000946 (Reaction Tree)
Reactant Type
 EDC
Mol
 40 micro mole
MOLECULE ID
 JCGG-COM0000415
Reactant Type
 Pd(OH)2/C
Weight
 1mg
PRODUCT
MOLECULE ID
 JCGG-COM0001000 (Reaction Tree)
Skeleton
JCGG-STR032134
Yield
 49%
REACTION DETAIL
Reaction Time
 3 + 20 hours, 6 hours
Reaction Temp
 room temp, room temp
Solvent
 CH2Cl2, MeOH
Comment
 1) 98+Et3N, HOBt, 92, EDC, 2) +Pd(OH)2
The reactants were mixed at 0 degree in Celsius before stirred at room temperature. (first phase)
98 was evaporated in Vacuo before the reaction. (3 hours)
COMMENT
The PMID could not be found.
There are two phases in this reaction.
REFERENCE
Reference Id
 REF-0000-000038
Source
 J. Am. Chem. Soc. 1996, 118, 6826-6840
Doi
 10.1021/ja952265x
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)