JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
 JCGG-RAC0000838
Submitter
 The Noguchi Institute
Reaction ID
 R-0000-000838
Regist Date
 2012/06/21 16:25:47
REACTANT
MOLECULE ID
 JCGG-COM0000918 (Reaction Tree)
Skeleton
JCGG-STR032134
Reactant Type
 dissolved in 30% TFA in CH2Cl2
Mol
 0.11 mmol
MOLECULE ID
 JCGG-COM0000047
Reactant Type
 Et3N
MOLECULE ID
 JCGG-COM0000578
Reactant Type
 HOBt
MOLECULE ID
 JCGG-COM0000955
Reactant Type
 dissolved in a mixture of TFA and CH2Cl2 (1/1)
MOLECULE ID
 JCGG-COM0000946 (Reaction Tree)
Reactant Type
 EDC
MOLECULE ID
 JCGG-COM0000415
Reactant Type
 Pd(OH)2/C
PRODUCT
MOLECULE ID
 JCGG-COM0000956 (Reaction Tree)
Skeleton
JCGG-STR032134
Yield
 48%
REACTION DETAIL
Reaction Time
 15 hours, 8 hours
Reaction Temp
 room temp, room temp
Solvent
 CH2Cl2, MeOH
Comment
 1) 47+Et3N, HOBt, 84, EDC, 2) +Pd(OH)2
The reactants were mixed at 0 degree in Celsius before stirred at room temperature. (first phase)
47 was evaporated in Vacuo before the reaction.
84 was allowed to stand for 3 hours at room temperature and evaporated in Vacuo before the reaction.
COMMENT
The PMID could not be found.
There are two phases in this reaction.
REFERENCE
Reference Id
 REF-0000-000038
Source
 J. Am. Chem. Soc. 1996, 118, 6826-6840
Doi
 10.1021/ja952265x
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)