JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
 JCGG-RAC0000827
Submitter
 The Noguchi Institute
Reaction ID
 R-0000-000827
Regist Date
 2012/06/21 16:25:11
REACTANT
MOLECULE ID
 JCGG-COM0000934 (Reaction Tree)
Skeleton
JCGG-STR025272
Mol
 23.4 micro mole
MOLECULE ID
 JCGG-COM0000881 (Reaction Tree)
Skeleton
JCGG-STR032526
Reactant Type
 alpha
Mol
 94.6 micro mole (alpha/beta=33/67)
MOLECULE ID
 JCGG-COM0000882 (Reaction Tree)
Skeleton
JCGG-STR031555
Reactant Type
 beta
Mol
 94.6 micro mole (alpha/beta=33/67)
MOLECULE ID
 JCGG-COM0000009
Reactant Type
 TMSOTf (10% in CH2Cl2)
Mol
 7.2 micro mole
PRODUCT
MOLECULE ID
 JCGG-COM0000935 (Reaction Tree)
Skeleton
JCGG-STR025761
Yield
 29%
REACTION DETAIL
Reaction Time
 10 minutes, 10 minutes, 20 hours
Reaction Temp
 -20 degree C, -20 degree C, 40 degree C
Solvent
 CH2Cl2, CH2Cl2, CH2Cl2
Comment
 1) TMSOTf+52, MS 4A, 2) +12, 3) temperature change
Molecular sieves (4 A) was included in the solvent.
COMMENT
The PMID could not be found.
There are three phases in this reaction.
REFERENCE
Reference Id
 REF-0000-000038
Source
 J. Am. Chem. Soc. 1996, 118, 6826-6840
Doi
 10.1021/ja952265x
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)