JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
 JCGG-RAC0000809
Submitter
 The Noguchi Institute
Reaction ID
 R-0000-000809
Regist Date
 2012/06/21 16:24:18
REACTANT
MOLECULE ID
 JCGG-COM0000893 (Reaction Tree)
Reactant Type
 Fucopyranosyl phosphite
Mol
 0.8 equiv.
MOLECULE ID
 JCGG-COM0000897 (Reaction Tree)
Skeleton
JCGG-STR026084
Reactant Type
 Acceptor
Mol
 1 equiv.
MOLECULE ID
 JCGG-COM0000111
Reactant Type
 TfOH
Mol
 0.05 equiv.
PRODUCT
MOLECULE ID
 JCGG-COM0000898 (Reaction Tree)
Skeleton
JCGG-STR001559
Yield
 38%
REACTION DETAIL
Reaction Time
 1 hour
Reaction Temp
 -15 degree C
Solvent
 CH2Cl2
Comment
 Molecular sieves (4 A) was included in the solvent.
COMMENT
The PMID could not be found.
The ratio of four diastereomers could not be known due to the complex 1H NMR spectrum.
It was estimated on the basis of the 1H and 13C NMR that the major product was bis-alpha-L-fucoside.
REFERENCE
Reference Id
 REF-0000-000038
Source
 J. Am. Chem. Soc. 1996, 118, 6826-6840
Doi
 10.1021/ja952265x
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)