JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
 JCGG-RAC0000747
Submitter
 The Noguchi Institute
Reaction ID
 R-0000-000747
Regist Date
 2012/06/21 16:21:35
REACTANT
MOLECULE ID
 JCGG-COM0000829 (Reaction Tree)
Skeleton
JCGG-STR031569
MOLECULE ID
 JCGG-COM0000830
Reactant Type
 DBTO
MOLECULE ID
 JCGG-COM0000831
Reactant Type
 PMBCl
MOLECULE ID
 JCGG-COM0000832
Reactant Type
 TBAB
PRODUCT
MOLECULE ID
 JCGG-COM0000833 (Reaction Tree)
Skeleton
JCGG-STR031569
Yield
 61%
MOLECULE ID
 JCGG-COM0000834 (Reaction Tree)
Skeleton
JCGG-STR031569
Yield
 35%
REACTION DETAIL
Reaction Temp
 reflux, 80 degree C
Solvent
 PhCH3, PhCH3
Comment
 1), 25+DBTO, 2) +PMBCl, TBAB
COMMENT
There are two phases in this reaction.
REFERENCE
Reference Id
 REF-0000-000035
Issn
 Electronic
Doi
 10.1021/jo8027888
PubMed ID
 19296672
Journal Name
 The Journal of organic chemistry. (2009) 74 (8): 3009-23.
Article Title
 Ganglioside GQ1b: efficient total synthesis and the expansion to synthetic derivatives to elucidate its biological roles.
Author
 Akihiro, Imamura; Hiromune, Ando; Hideharu, Ishida; Makoto, Kiso
Affiliation
 Department of Applied Bioorganic Chemistry, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu-shi, Gifu 501-1193, Japan. aimamura@ualberta.ca
Reference Id
 REF-0000-000036
Source
 J. Org. Chem. 2009, 74, 3009-3023
Doi
 10.1021/jo8027888
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)