JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
JCGG-RAC0000728
Submitter
The Noguchi Institute
Reaction ID
R-0000-000728
Regist Date
2012/06/21 16:20:40
REACTANT
MOLECULE ID
JCGG-COM0000497 (Reaction Tree)
MOLECULE ID
JCGG-COM0000375
Reactant Type
PhCH(OMe)2
MOLECULE ID
JCGG-COM0000277
Reactant Type
CSA
MOLECULE ID
JCGG-COM0000808
Reactant Type
TrocCl
PRODUCT
MOLECULE ID
JCGG-COM0000809 (Reaction Tree)
Yield
90%
REACTION DETAIL
Solvent
MeCN/THF = 2/1, Py
Comment
1) 7+PhCH(OMe)2, CSA, 2) +TrocCl
Very few were described regarding this reaction.
COMMENT
There are two phases in this reaction.
REFERENCE
Reference Id
REF-0000-000035
Issn
Electronic
Doi
10.1021/jo8027888
PubMed ID
19296672
Journal Name
The Journal of organic chemistry. (2009) 74 (8): 3009-23.
Article Title
Ganglioside GQ1b: efficient total synthesis and the expansion to synthetic derivatives to elucidate its biological roles.
Author
Akihiro, Imamura; Hiromune, Ando; Hideharu, Ishida; Makoto, Kiso
Affiliation
Department of Applied Bioorganic Chemistry, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu-shi, Gifu 501-1193, Japan. aimamura@ualberta.ca
Reference Id
REF-0000-000036
Source
J. Org. Chem. 2009, 74, 3009-3023
Doi
10.1021/jo8027888

©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)