JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
JCGG-RAC0000625
Submitter
The Noguchi Institute
Reaction ID
R-0000-000625
Regist Date
2012/06/21 16:15:40
REACTANT
MOLECULE ID
JCGG-COM0000641 (Reaction Tree)
Mol
0.067 mmol
MOLECULE ID
JCGG-COM0000669
Reactant Type
succinimidyl ester (in MeCN)
Mol
0.08 mmol
MOLECULE ID
JCGG-COM0000549
Reactant Type
NaHCO3 (buffer)
PRODUCT
MOLECULE ID
JCGG-COM0000670 (Reaction Tree)
Yield
85%
REACTION DETAIL
Reaction Time
24 hours
Reaction Temp
room temp
Solvent
MeCN/H2O = 5/1
COMMENT
REFERENCE
Reference Id
REF-0000-000028
Issn
Electronic
Doi
10.1021/jm8000696
PubMed ID
18841881
Journal Name
Journal of medicinal chemistry. (2008) 51 (21): 6665-81.
Article Title
Design, synthesis, and structure-affinity relationships of novel series of sialosides as CD22-specific inhibitors.
Author
Hajjaj H M, Abdu-Allah; Taichi, Tamanaka; Jie, Yu; Lu, Zhuoyuan; Magesh, Sadagopan; Takahiro, Adachi; Takeshi, Tsubata; Soerge, Kelm; Hideharu, Ishida; Makoto, Kiso
Affiliation
Department of Applied Bio-organic Chemistry, The United Graduate School of Agricultural Sciences, Gifu University, Gifu 501-1193, Japan.
Reference Id
REF-0000-000029
Source
J. Med. Chem., 2008, 51, 6665-6681
Doi
10.1021/jm8000696

©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)