JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
 JCGG-RAC0000603
Submitter
 The Noguchi Institute
Reaction ID
 R-0000-000603
Regist Date
 2012/06/21 16:14:37
REACTANT
MOLECULE ID
 JCGG-COM0000611 (Reaction Tree)
Mol
 44.7 micro mole
MOLECULE ID
 JCGG-COM0000623
Reactant Type
 zinc powder
Weight
 176 mg
MOLECULE ID
 JCGG-COM0000491
Reactant Type
 acetic acid
Volume
 600 microL
MOLECULE ID
 JCGG-COM0000086
Reactant Type
 Ac2O
Mol
 447 micro mole
PRODUCT
MOLECULE ID
 JCGG-COM0000620 (Reaction Tree)
Skeleton
JCGG-STR025711
Yield
 89%
REACTION DETAIL
Reaction Time
 1 hours, 1 hours
Reaction Temp
 40 degree C, 40 degree C
Solvent
 anhydrous dichloroethane, anhydrous dichloroethane
Comment
 1) 9+zinc powder, acetic acid, 2) +Ac2O
COMMENT
There are two phases in this reaction.
REFERENCE
Reference Id
 REF-0000-000026
Issn
 Print
Doi
 10.1021/ol051592z
PubMed ID
 16178547
Journal Name
 Organic letters. (2005) 7 (20): 4415-8.
Article Title
 Di-tert-butylsilylene-directed alpha-selective synthesis of 4-methylumbelliferyl T-antigen.
Author
 Akihiro, Imamura; Hiromune, Ando; Hideharu, Ishida; Makoto, Kiso
Affiliation
 Department of Applied Bioorganic Chemistry, Gifu University, Gifu 501-1193, Japan.
Reference Id
 REF-0000-000027
Source
 ORGANIC LETTERS, 2005, Vol. 7, No. 20, 4415-4418
Doi
 10.1021/ol051592z
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)