JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
 JCGG-RAC0000533
Submitter
 The Noguchi Institute
Reaction ID
 R-0000-000534
Regist Date
 2012/06/21 16:11:20
REACTANT
MOLECULE ID
 JCGG-COM0000515 (Reaction Tree)
Reactant Type
 Donor
Mol
 69 micro mole
MOLECULE ID
 JCGG-COM0000513 (Reaction Tree)
Skeleton
JCGG-STR004355
Reactant Type
 GM2 acceptor
Mol
 34 micro mole
MOLECULE ID
 JCGG-COM0000129
Reactant Type
 Promoter
Mol
 173 micro mole
MOLECULE ID
 JCGG-COM0000111
Reactant Type
 Promoter
Mol
 17 micro mole
PRODUCT
MOLECULE ID
 JCGG-COM0000529 (Reaction Tree)
Skeleton
JCGG-STR002614
Yield
 75%
REACTION DETAIL
Reaction Time
 1 hour, 2 hours
Reaction Temp
 room temp, 0 degree C
Solvent
 CH2Cl2
Catalyst
 Promoter
Comment
 MS 4A was included in the solvent.
1) 26+24+MS 4A, 2) +Promoters
COMMENT
There are two phases in this reaction.
ATTENTION: There are numerical discrepancies between the table and the written method. (the number of equiv.)
REFERENCE
Reference Id
 REF-0000-000021
Issn
 Electronic
Doi
 10.1016/j.carres.2009.06.009
PubMed ID
 19560125
Journal Name
 Carbohydrate research. (2009) 344 (12): 1453-63.
Article Title
 Study on systematizing the synthesis of the a-series ganglioside glycans GT1a, GD1a, and GM1 using the newly developed N-Troc-protected GM3 and GalN intermediates.
Author
 Tatsuya, Komori; Akihiro, Imamura; Hiromune, Ando; Hideharu, Ishida; Makoto, Kiso
Affiliation
 Department of Applied Bioorganic Chemistry, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu-shi, Gifu 501-1193, Japan.
Reference Id
 REF-0000-000022
Source
 Carbohydrate Research, 344 (2009), 1453-1463
Doi
 10.1016/j.carres.2009.06.009
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)