JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
 JCGG-RAC0000526
Submitter
 The Noguchi Institute
Reaction ID
 R-0000-000527
Regist Date
 2012/06/21 16:10:55
REACTANT
MOLECULE ID
 JCGG-COM0000516 (Reaction Tree)
Mol
 132 micro mole
MOLECULE ID
 JCGG-COM0000517
Reactant Type
 ClP(OEt)2
Mol
 266 micro mole
MOLECULE ID
 JCGG-COM0000426
Reactant Type
 DIEA
Mol
 398 micro mole
PRODUCT
MOLECULE ID
 JCGG-COM0000518 (Reaction Tree)
Skeleton
JCGG-STR023749
Product Type
 alpha
Yield
 73%(alpha/beta=1/1.8)
MOLECULE ID
 JCGG-COM0000519 (Reaction Tree)
Skeleton
JCGG-STR024648
Product Type
 beta
Yield
 73%(alpha/beta=1/1.8)
REACTION DETAIL
Reaction Time
 1 hour
Reaction Temp
 room temp
Solvent
 CH3CN
Comment
 The reactants were mixed at 0 degree in Celsius before stirred at room temperature.
COMMENT
REFERENCE
Reference Id
 REF-0000-000021
Issn
 Electronic
Doi
 10.1016/j.carres.2009.06.009
PubMed ID
 19560125
Journal Name
 Carbohydrate research. (2009) 344 (12): 1453-63.
Article Title
 Study on systematizing the synthesis of the a-series ganglioside glycans GT1a, GD1a, and GM1 using the newly developed N-Troc-protected GM3 and GalN intermediates.
Author
 Tatsuya, Komori; Akihiro, Imamura; Hiromune, Ando; Hideharu, Ishida; Makoto, Kiso
Affiliation
 Department of Applied Bioorganic Chemistry, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu-shi, Gifu 501-1193, Japan.
Reference Id
 REF-0000-000022
Source
 Carbohydrate Research, 344 (2009), 1453-1463
Doi
 10.1016/j.carres.2009.06.009
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)