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Glycan Syntheses |
JCGG ID |
JCGG-RAC0000525 | ||||
Submitter |
The Noguchi Institute | ||||
Reaction ID |
R-0000-000526
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Regist Date |
2012/06/21 16:10:51 | ||||
| REACTANT | |||||
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Mol |
1.00 mmol | ||||
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Reactant Type |
PhBCl2 | ||||
Mol |
3.43 mmol | ||||
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Reactant Type |
Et3SiH | ||||
Mol |
3.02 mmol | ||||
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Reactant Type |
Ac2O | ||||
Mol |
5.04 mmol | ||||
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Reactant Type |
DMAP | ||||
Volume |
catalytic amount | ||||
| PRODUCT | |||||
MOLECULE ID |
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Yield |
85% | ||||
| REACTION DETAIL | |||||
Reaction Time |
2 hours, 1.5 hours, 14 hours | ||||
Reaction Temp |
room temp, -78 degree C, room temp | ||||
Solvent |
CH2Cl2, CH2Cl2, pyridine | ||||
Comment |
AW-300 was included in the solvent. | ||||
| 1) 25+AW-300, 2) Et3SiH, PhBCl2, 3) Ac2O, DMAP | |||||
| COMMENT | |||||
| There are three phases in this reaction. | |||||
| REFERENCE | |||||
Reference Id |
REF-0000-000021 | ||||
Issn |
Electronic | ||||
Doi |
10.1016/j.carres.2009.06.009 | ||||
PubMed ID |
19560125 | ||||
Journal Name |
Carbohydrate research. (2009) 344 (12): 1453-63. | ||||
Article Title |
Study on systematizing the synthesis of the a-series ganglioside glycans GT1a, GD1a, and GM1 using the newly developed N-Troc-protected GM3 and GalN intermediates. | ||||
Author |
Tatsuya, Komori; Akihiro, Imamura; Hiromune, Ando; Hideharu, Ishida; Makoto, Kiso | ||||
Affiliation |
Department of Applied Bioorganic Chemistry, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu-shi, Gifu 501-1193, Japan. | ||||
Reference Id |
REF-0000-000022 | ||||
Source |
Carbohydrate Research, 344 (2009), 1453-1463 | ||||
Doi |
10.1016/j.carres.2009.06.009 | ||||
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)
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