JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
 JCGG-RAC0000516
Submitter
 The Noguchi Institute
Reaction ID
 R-0000-000517
Regist Date
 2012/06/21 16:10:22
REACTANT
MOLECULE ID
 JCGG-COM0000492 (Reaction Tree)
Skeleton
JCGG-STR004355
Reactant Type
 3,4-diol acceptor
MOLECULE ID
 JCGG-COM0000493 (Reaction Tree)
Reactant Type
 galactosyl donor
MOLECULE ID
 JCGG-COM0000129
Reactant Type
 NIS
MOLECULE ID
 JCGG-COM0000111
Reactant Type
 TfOH
PRODUCT
MOLECULE ID
 JCGG-COM0000494 (Reaction Tree)
Skeleton
JCGG-STR002614
Product Type
 GM1
Yield
 66%
MOLECULE ID
 JCGG-COM0000495 (Reaction Tree)
Product Type
 4-O-galactosyl
MOLECULE ID
 JCGG-COM0000496 (Reaction Tree)
Product Type
 3,4-di-O-galactosyl
REACTION DETAIL
Reaction Temp
 room temp
Solvent
 CH2Cl2
Comment
 Very few were described regarding this reaction.
COMMENT
The details regarding this reaction are described in another paper in References.
REFERENCE
Reference Id
 REF-0000-000021
Issn
 Electronic
Doi
 10.1016/j.carres.2009.06.009
PubMed ID
 19560125
Journal Name
 Carbohydrate research. (2009) 344 (12): 1453-63.
Article Title
 Study on systematizing the synthesis of the a-series ganglioside glycans GT1a, GD1a, and GM1 using the newly developed N-Troc-protected GM3 and GalN intermediates.
Author
 Tatsuya, Komori; Akihiro, Imamura; Hiromune, Ando; Hideharu, Ishida; Makoto, Kiso
Affiliation
 Department of Applied Bioorganic Chemistry, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu-shi, Gifu 501-1193, Japan.
Reference Id
 REF-0000-000022
Source
 Carbohydrate Research, 344 (2009), 1453-1463
Doi
 10.1016/j.carres.2009.06.009
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)