JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
 JCGG-RAC0000513
Submitter
 The Noguchi Institute
Reaction ID
 R-0000-000514
Regist Date
 2012/06/21 16:10:12
REACTANT
MOLECULE ID
 JCGG-COM0000424 (Reaction Tree)
Skeleton
JCGG-STR008690
Mol
 0.62 mmol
MOLECULE ID
 JCGG-COM0000484
Reactant Type
 Ozone gas
MOLECULE ID
 JCGG-COM0000408
Mol
 1.9 mmol
MOLECULE ID
 JCGG-COM0000485
Reactant Type
 Sodium chlorite
Mol
 6.2 mmol
MOLECULE ID
 JCGG-COM0000486
Mol
 0.74 mmol
MOLECULE ID
 JCGG-COM0000487
Mol
 2.9 mmol
PRODUCT
MOLECULE ID
 JCGG-COM0000425 (Reaction Tree)
Skeleton
JCGG-STR008690
Yield
 70%
REACTION DETAIL
Reaction Time
 2 hours, 2hours, 15 hours
Reaction Temp
 -78 degree C, room temp, room temp
Solvent
 CH2Cl2, CH2Cl2, t-buOH/H2O=10/2
Comment
 1) O3 gas, 2) Ph3P, 3) NaClO2, NaH2PO4, 2-methyl-2-butene, t-BuOH, H2O, 70%
COMMENT
There are three phases in this reaction.
REFERENCE
Reference Id
 REF-0000-000016
Issn
 Print
PubMed ID
 19122320
Journal Name
 Chemical & pharmaceutical bulletin. (2009) 57 (1): 74-8.
Article Title
 Syntheses and doxorubicin-inclusion abilities of beta-cyclodextrin derivatives with a hydroquinone alpha-glycoside residue attached at the primary side.
Author
 Yoshiki, Oda; Masumi, Miura; Kenjiro, Hattori; Takashi, Yamanoi
Affiliation
 The Noguchi Institute, Tokyo, Japan.
Reference Id
 REF-0000-000017
Source
 CHEMICAL & PHARMACEUTICAL BULLETIN, Vol. 57 (2009), No. 1, 74
Doi
 10.1248/cpb.57.74
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)