JCGGDB TOP Glycan Syntheses

Reaction

JCGG ID
 JCGG-RAC0000213
Submitter
 The Noguchi Institute
Reaction ID
 R-0000-000213
Regist Date
 2012/06/21 14:53:02
REACTANT
MOLECULE ID
 JCGG-COM0000226 (Reaction Tree)
Reactant Type
 Donor[1,3,4,6-tetra-O-benzyl-D-frucofuranosyl acetate (alpha/beta=1/2)]
Mol
 1
MOLECULE ID
 JCGG-COM0000006
Reactant Type
 Activator
Mol
 0.05
MOLECULE ID
 JCGG-COM0000248 (Reaction Tree)
Skeleton
JCGG-STR025316
Reactant Type
 Acceptor
Mol
 1
PRODUCT
MOLECULE ID
 JCGG-COM0000249 (Reaction Tree)
Product Type
 alpha+alpha
Yield
 65%(alpha+alpha/alpha+beta=94/6)
MOLECULE ID
 JCGG-COM0000250 (Reaction Tree)
Product Type
 alpha+beta
Yield
 65%(alpha+alpha/alpha+beta=94/6)
REACTION DETAIL
Reaction Time
 0.5 hour to overnight
Reaction Temp
 0 degree C
Solvent
 CH2Cl2
Catalyst
 Activator
Comment
 Anhydrous CaSO4 was included in the solvent.
COMMENT
The PMID could not be found.
Only alpha+alpha and alpha+beta was detected in the product.
CH2Cl2 was used as the solvent due to the poor solubility of aldopyranoses in PhCH3
REFERENCE
Reference Id
 REF-0000-000011
Source
 Tetrahedron Letters 48 (2007) 6458‐6462
Doi
 10.1016/j.tetlet.2007.07.092
©2008-2013 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)