Pathogen Adherence to Carbohydrate DB

This database provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants. Many pathogens have been reported to recognize the sugar moieties of host cells as a first step of bacterial adhesion and infection. We have also collected the data of diseases caused by bacterial infections to host tissues.

This database will give you easy access to the data on each pathogen and its receptor glycans or proteins.

We hope that this database could be of help in your study and serve as a bridge for two areas of study, glycoscience and infectious diseases.

Project Members

Masako Maeda, RCMG, AIST.

Mihou Fushimi (Graphic Design), RCMG, AIST.

Toshihide Shikanai, RCMG, AIST.

Hisashi Narimatsu, RCMG, AIST.

Disclaimer

Liability: For documents with data and tools available from this server, JCGGDB & AIST does not warrant or assume any legal liability or responsibility for the accuracy, completeness, or usefulness of any information, apparatus, product, or process disclosed.

Acknowledgements

This database is supported by Ministry of Education, Culture, Sports, Science and Technology (MEXT) as part of Life Science Integrated Database project.

Extraction from 216 References

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PACDB REF. ID	Pathogen Adherence Molecule	Glycan/Glycoprotein Ligand
8	Helicobacter pylori (17874/17875/032) Binding Adhesin:Adhesins	Human leukocytes, Human neutrophils NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
8	Helicobacter pylori (17874/17875/032) Binding Adhesin:Adhesins	Human leukocytes, Human neutrophils NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
12	Influenza virus (A; H4N6; avian) Binding Unclassfied Protein:Hemagglutinin (HA)	Various human tissues (leukocytes/erythrocytes/small intestine/stomach/meconium/colon/pancreas) NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
14	Lactobacillus johnsonii (La1) Not Binding Unclassfied Protein:Unknown	Human erythrocytes NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
25	Influenza virus (A/Mem/1/71-Bel/42; H3N1) Binding Unclassfied Protein:Hemagglutinin (HA)	NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
33	Helicobacter pylori (CCUG 17874) Binding Unclassfied Protein:Unknown	NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
47	Actinomyces naeslundii (ATCC 12104) Not Binding Unclassfied Protein:Unknown	Human erythrocytes NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
47	Actinomyces viscosus (ATCC 19246) Not Binding Unclassfied Protein:Unknown	Human erythrocytes NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
49	Mycoplasma pneumoniae (M129; virulent) Not Binding Unclassfied Protein:Unknown	Human colon adenocarcinoma cells (WiDr ) NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
60	Escherichia coli Not Binding Unclassfied Protein:Unknown	NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
60	Vibrio cholerae Not Binding Unclassfied Protein:Unknown	NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
66	Influenza virus (A/PR/8/34; H1N1; human) Binding Unclassfied Protein:Unknown	NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
66	Influenza virus (B/Lee/40; human) Not Binding Unclassfied Protein:Unknown	NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
66	Influenza virus (C/Ann Arbor/1/50; human) Not Binding Unclassfied Protein:Unknown	NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
78	Lactobacillus casei (IFO 3425) Not Binding Unclassfied Protein:Unknown	Intestinal tract NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
82	Helicobacter pylori (NCTC 11637) Binding Unclassfied Protein:Unknown	NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
84	Helicobacter pylori Not Binding Unclassfied Protein:Neutrophil-activating proteins (150-kDa)	Human granulocytes NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
103	Rotavirus (Neuraminidase-insensitive; bovine:UK(P5/G6)) Binding Unclassfied Protein:Unknown	NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
103	Rotavirus (Neuraminidase-sensitive; simian:SA11(P2/G3) / bovine:NCDV(P1/G6)) Binding Unclassfied Protein:Unknown	NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
117	Escherichia coli (Uropathogenic(UPEC); ARD6; serotype O6:K13:H1) Not Binding Adhesin:F1C	Human erythrocytes NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
135	Influenza virus (A/PR/8/34; H1N1) Binding Unclassfied Protein:Unknown	Granulocytes NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
135	Sendai virus (Z) Binding Unclassfied Protein:Unknown	Granulocytes NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
137	Cytomegalovirus (HCMV; human) Not Binding Unclassfied Protein:Unknown	NeuAc3-nLc4 (sialyl paragloboside; S-3-PG) NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]