Pathogen Adherence to Carbohydrate DB

This database provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants. Many pathogens have been reported to recognize the sugar moieties of host cells as a first step of bacterial adhesion and infection. We have also collected the data of diseases caused by bacterial infections to host tissues.

This database will give you easy access to the data on each pathogen and its receptor glycans or proteins.

We hope that this database could be of help in your study and serve as a bridge for two areas of study, glycoscience and infectious diseases.

Project Members

Masako Maeda, RCMG, AIST.

Mihou Fushimi (Graphic Design), RCMG, AIST.

Toshihide Shikanai, RCMG, AIST.

Hisashi Narimatsu, RCMG, AIST.

Disclaimer

Liability: For documents with data and tools available from this server, JCGGDB & AIST does not warrant or assume any legal liability or responsibility for the accuracy, completeness, or usefulness of any information, apparatus, product, or process disclosed.

Acknowledgements

This database is supported by Ministry of Education, Culture, Sports, Science and Technology (MEXT) as part of Life Science Integrated Database project.

Extraction from 216 References

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PACDB REF. ID	Pathogen Adherence Molecule	Glycan/Glycoprotein Ligand
25	Influenza virus (A/Mem/1/71-Bel/42; H3N1) Binding Unclassfied Protein:Hemagglutinin (HA)	NeuAc6-nLc4 (sialyl paragloboside) NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
66	Influenza virus (A/PR/8/34; H1N1; human) Binding Unclassfied Protein:Unknown	NeuAc6-nLc4 (sialyl paragloboside) NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
66	Influenza virus (B/Lee/40; human) Binding Unclassfied Protein:Unknown	NeuAc6-nLc4 (sialyl paragloboside) NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
66	Influenza virus (C/Ann Arbor/1/50; human) Not Binding Unclassfied Protein:Unknown	NeuAc6-nLc4 (sialyl paragloboside) NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
82	Helicobacter pylori (NCTC 11637) Not Binding Unclassfied Protein:Unknown	NeuAc6-nLc4 (sialyl paragloboside) NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
84	Helicobacter pylori Not Binding Unclassfied Protein:Neutrophil-activating proteins (150-kDa)	Human meconium NeuAc6-nLc4 (sialyl paragloboside) NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
103	Rotavirus (Neuraminidase-sensitive; simian:SA11(P2/G3)) Binding Unclassfied Protein:Unknown	NeuAc6-nLc4 (sialyl paragloboside) NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
135	Influenza virus (A/PR/8/34; H1N1) Binding Unclassfied Protein:Unknown	Granulocytes NeuAc6-nLc4 (sialyl paragloboside) NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
135	Influenza virus (A/X-31; H3N2) Binding Unclassfied Protein:Unknown	Granulocytes NeuAc6-nLc4 (sialyl paragloboside) NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]