Pathogen Adherence to Carbohydrate DB

This database provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants. Many pathogens have been reported to recognize the sugar moieties of host cells as a first step of bacterial adhesion and infection. We have also collected the data of diseases caused by bacterial infections to host tissues.

This database will give you easy access to the data on each pathogen and its receptor glycans or proteins.

We hope that this database could be of help in your study and serve as a bridge for two areas of study, glycoscience and infectious diseases.

Project Members

Masako Maeda, RCMG, AIST.

Mihou Fushimi (Graphic Design), RCMG, AIST.

Toshihide Shikanai, RCMG, AIST.

Hisashi Narimatsu, RCMG, AIST.

Disclaimer

Liability: For documents with data and tools available from this server, JCGGDB & AIST does not warrant or assume any legal liability or responsibility for the accuracy, completeness, or usefulness of any information, apparatus, product, or process disclosed.

Acknowledgements

This database is supported by Ministry of Education, Culture, Sports, Science and Technology (MEXT) as part of Life Science Integrated Database project.

Extraction from 216 References

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PACDB REF. ID	Pathogen Adherence Molecule	Glycan/Glycoprotein Ligand
10	Escherichia coli (Uropathogenic(UPEC); K12/HB101(pPIL110-54)) Not Binding Adhesin:F1C Genomic Name:foc (cluster of 8 genes)	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
21	Escherichia coli (Enterotoxigenic(ETEC); K88) Binding Adhesin:K88ac	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
21	Escherichia coli (Enterotoxigenic(ETEC); K88) Not Binding Adhesin:K88ab/K88ad	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
25	Influenza virus (A/Mem/1/71-Bel/42; H3N1) Binding Unclassfied Protein:Hemagglutinin (HA)	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
25	Influenza virus (A/Mem/1/71-Bel/42; H3N1) Binding Unclassfied Protein:Hemagglutinin (HA)	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
25	Rotavirus (UK) Binding Unclassfied Protein:Unknown	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
25	Helicobacter pylori Binding Unclassfied Protein:Unknown	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
25	Helicobacter pylori Binding Unclassfied Protein:Unknown	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
28	Legionella pneumophila (CORBY) Not Binding Adhesin:Adhesins	Human epithelial cells (respiratory tract) GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
47	Actinomyces naeslundii (ATCC 12104) Not Binding Unclassfied Protein:Unknown	Human erythrocytes GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
47	Actinomyces viscosus (ATCC 19246) Not Binding Unclassfied Protein:Unknown	Human erythrocytes GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
49	Mycoplasma pneumoniae (M129; virulent) Not Binding Unclassfied Protein:Unknown	Human colon adenocarcinoma cells (WiDr ) GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
51	Escherichia coli (41) Binding Unclassfied Protein:A and B polypeptide subunits	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
51	Escherichia coli (HB101(pCP3727)) Binding Unclassfied Protein:A and B polypeptide subunits	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
60	Vibrio cholerae Not Binding Unclassfied Protein:Unknown	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
60	Escherichia coli Not Binding Unclassfied Protein:Unknown	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
60	Clostridium tetani Not Binding Unclassfied Protein:Unknown	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
66	Influenza virus (A/PR/8/34; H1N1; human) Binding Unclassfied Protein:Unknown	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
66	Influenza virus (B/Lee/40; human) Not Binding Unclassfied Protein:Unknown	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
66	Influenza virus (C/Ann Arbor/1/50; human) Not Binding Unclassfied Protein:Unknown	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
78	Lactobacillus casei (IFO 3425) Not Binding Unclassfied Protein:Unknown	Intestinal tract GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
82	Helicobacter pylori (NCTC 11637) Not Binding Unclassfied Protein:Unknown	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
84	Helicobacter pylori Not Binding Unclassfied Protein:Neutrophil-activating proteins (150-kDa)	Human granulocytes GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
87	Helicobacter pylori (1139/17874/17875/11637/11638) Not Binding Unclassfied Protein:35S-labeled or 125I-labeled proteins	Human brain GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
91	Escherichia coli (HB101(pDG1)) Not Binding Adhesin:PsaA/B (pH-6 antigen) Genomic Name:psaA/B	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
91	Yersinia pestis (pH6 antigen from Escherichia coli(HB101)) Not Binding Adhesin:PsaA/B (pH-6 antigen) Genomic Name:psaA/B	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
103	Rotavirus (Neuraminidase-insensitive; bovine:UK(P5/G6)) Binding Unclassfied Protein:Unknown	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
103	Rotavirus (Neuraminidase-sensitive; simian:SA11(P2/G3) / bovine:NCDV(P1/G6)) Not Binding Unclassfied Protein:Unknown	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
117	Escherichia coli (Uropathogenic(UPEC); ARD6; serotype O6:K13:H1) Not Binding Adhesin:F1C	Human brain GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Not Binding ]
132	Influenza virus (C; Johannesburg/1/66; synthetically O-acetylated) Binding Unclassfied Protein:Unknown	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
135	Influenza virus (A/PR/8/34; H1N1) Binding Unclassfied Protein:Unknown	Granulocytes GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
136	Rotavirus (OSU; porcine) Binding Unclassfied Protein:Unknown	GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]
245	Helicobacter pylori Binding Adhesin:Adhesins	Human gastric mucosa GM3 NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer [ Binding ]