JCGG-STR014560:JCGGDB ID

JCGGDB Glycan Structure Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)

Glycan Information

Glyco Tree get Image

Composition

Hex 3 HexNAc 1 Neu5Ac 2
Mass Value Search

Gal 2 GalNAc 1 Glc 1 Neu5Ac 2
Structural Isomer Search

Descriptors Computed from Structure

InChIKey	OYKVMTICVUABAD-AHTICSJKSA-N
InChI	InChI=1S/C48H79N3O37/c1-12(57)49-23-15(60)4-47(45(74)75,86-38(23)26(64)17(62)6-52)78-11-22-29(67)37(25(51-14(3)59)42(82-22)83-36-21(10-56)81-43(33(71)31(36)69)84-35-20(9-55)79-41(73)32(70)30(35)68)85-44-34(72)40(28(66)19(8-54)80-44)88-48(46(76)77)5-16(61)24(50-13(2)58)39(87-48)27(65)18(63)7-53/h15-44,52-56,60-73H,4-11H2,1-3H3,(H,49,57)(H,50,58)(H,51,59)(H,74,75)(H,76,77)/t15-,16-,17+,18+,19+,20+,21+,22+,23+,24+,25+,26+,27+,28-,29-,30+,31+,32+,33+,34+,35+,36-,37+,38+,39+,40-,41+,42-,43-,44-,47+,48-/m0/s
SMILES	CC(=O)N[C@@H]1[C@@H](O)C[C@@](OC[C@H]2O[C@@H](O[C@H]3[C@@H](CO)O[C@@H](O[C@@H]4[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O)[C@H](NC(C)=O)[C@@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O[C@@]4(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O4)[C@H](O)[C@H](O)CO)C(O)=O)[C@H]3O)[C@H]2O)(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O

Mass

	Monoisotopic Mass	Average Mass
Underivatised Oligosaccharides	1289.4391	1290.1532
Permethylated Oligosaccharides	1625.8149	1626.7982
Peracetylated Oligosaccharides	2087.6399	2088.8616

Glycan Motifs

Motif ID	Structure / SubStructure Name	Note
JCGG-MOTIF3003	ganglio	Reducing Terminal
JCGG-MOTIF4086	GD1 alpha(Pentasaccharide)	NON-Reducing Terminal

ID History Deleted Version

JCGG-STR031355(2)

External Links

GlycoEpitope (Antiglycan Antibody)

GlycoEpitope GLPD-000081 GLPD-000081

Name:   GD1 alpha
Description:   IV³Neu5AcIII⁶Neu5AcGg₄Cer
Reducing terminal:   (b-1)Cer

GMDB (MSⁿ)

GMDB OLG-00020b

JCGG	JCGG JGD-000523 JGD-000523 Reducing terminal: (b-1)Cer

LipidBank (Spectral Data)

LipidBank GSG1234 GSG1234

Name:   GD1a, GD1e
Description:   NeuAc2-3Galb1-3(NeuAc2-6)GalNAcb1-4Galb1-4GlcCer
Reducing terminal:   (b-)Cer

LipidBank GSG3013 GSG3013

Description: N-acetylneuraminyla2-3galactosylb1-3(N-acetylneuraminyla2-6)N-acetyl- -galactosaminylb1-4galactosylb1-4glucosylceramide
Reducing terminal: (b-)Cer

GlycomeDB (Structure)

GlycomeDB 2352 2352

KEGG (Structure)

KEGG G00127 G00127

PACDB(Pathogen adhesion)

Pathogen:	Actinomyces viscosus (ATCC 19246)
Glycan Name:	[ Not Binding]

Pathogen:	Actinomyces naeslundii (ATCC 12104)
Glycan Name:	[ Not Binding]

CarbBank

CCSD : 1086

Title : A ganglioside of rat ascites hepatoma AH 7974F cells. Occurrence of a novel disialoganglioside (GD1.alpha.) with a unique N-acetylneuraminosyl(.alpha.2-6)- N-acetylgalactosamine structure

Authors : Taki T; Hirabayashi Y; Ishikawa H; Ando S; Kon K; Tanaka Y; Matsumoto M

Info : J Biol Chem (1986) 261: 3075-3078

TAXID : 10116 Other Data : ascites cells Other Data : 2010-12-17

CCSD : 1087

Title : Appearance of a novel type of ganglioside (GD1.alpha.) in a differentiation resistance clone of mouse myeloid leukemia cells, M1-R1

Authors : Taki T; Maeda H; Arai K; Matsumoto M; Kon K; Ando S

Info : Cell Struct Funct (1988) 13: 61-72

TAXID : 10090 Other Data : myeloid leukemia Other Data : 2010-12-17

CCSD : 1088

Title : Qualitative differences in position of sialylation and surface expression of glycolipids between murine lymphomas with low metastatic disialoganglioside (GD1.alpha.) from Eb cells

Authors : Murayama K; Levery SB; Schirrmacher V; Hakomori SI

Info : Cancer Res (1986) 46: 1395-1402

TAXID : 10090 Other Data : 2010-12-17

CCSD : 6588

Title : Generation of a monoclonal antibody specific for a new class of minor ganglioside antigens, GQ1b.alpha. and GT1a.alpha.: its binding to dorsal and lateral horn of human thoracic cord

Authors : Kusunoki S; Chiba A; Hirabayashi Y; Irie F; Kotani M; Kawashima I; Tai T; Nagai Y

Info : Brain Res (1993) 623: 83-88

Other Data : 2010-12-17

CCSD : 6816

Title : Molecular cloning and function analysis of sialyltranferase

Authors : Tsuji S

Info : J Biochem (1996) 120: 1-13

Other Data : 2010-12-17

CCSD : 15941

Title : Fast atom bombardment mass spectrometry of glycosphingolipids

Authors : Sweeley CC; Gage DA; Ladisch S

Info : Iyo Masu Kenkyukai Koenshu (1988) 13: 43-49

Other Data : nerve Other Data : 2010-12-17

CCSD : 17797

Title : Structures of the pigments in the skin and the gangliosides in the brains of frogs

Authors : Munesada K; Yuasa T; Suga T

Info : Tennen Yuki Kagobutsu Toronkai Koen Yoshishu (1988) 30: 244-251

Other Data : brain Other Data : 2010-12-17

CCSD : 18551

Title : Inhibition of infection with human immunodeficiency virus type 1 by sulfated gangliosides

Authors : Handa A; Hoshino H; Nakajima K; Adachi M; Ikeda K; Achiwa K; Itoh T; Suzuki Y

Info : Biochem Biophys Res Commun (1991) 175: 1-9

Other Data : 2010-12-17

CCSD : 18653

Title : Gangliosides of murine T lymphocyte subpopulations

Authors : Muething J; Schwinzer B; Peter-Katalinic J; Egge H; Muehlradt PF

Info : Biochemistry (1989) 28: 2923-2929

TAXID : 10090 Other Data : T lymphocyte subpopulation Other Data : 2010-12-17

CCSD : 18891

Title : Interaction of ganglioside-containing planar bilayers with serotonin and inorganic cations

Authors : Matinyan NS; Melikyan GB; Arakelyan VB; Kocharov SL; Prokazova NV; Avakian TM

Info : Biochim Biophys Acta (1989) 984: 313-318

Other Data : 2010-12-17

CCSD : 20989

Title : Production and characterization of a monoclonal antibody (BBH5) directed to ganglioside lactone

Authors : Bouchon B; Levery SB; Clausen H; Hakomori SI

Info : Glycoconj J (1992) 9: 27-38

Other Data : 2010-12-17

CCSD : 21591

Title : Isolation and characterization of extremely minor gangliosides, GM1b and GD1.alpha. in adult bovine brains as developmentally regulated antigens

Authors : Hirabayashi Y; Hyogo A; Nakao T; Tsuchiya K; Suzuki Y; Matsumoto M; Kon K; Ando S

Info : J Biol Chem (1990) 265: 8144-8151

Other Data : brain, development Other Data : 2010-12-17

CCSD : 21942

Title : Novel gangliosides of frog brain. Establishment of the structures by their proton NMR and mass spectra

Authors : Munesada K; Nishikawa A; Suga T

Info : J Chem Soc Perkin Trans (1989) : 1491-1496

Other Data : brain Other Data : 2010-12-17

CCSD : 22741

Title : Glycosphingolipids in human uterine endometrium. Expression of sulfoglycolipids and its fluctuation during the menstrual cycle

Authors : Kubushiro K

Info : Nippon Sanka Fujinka Gakkai Zasshi (1989) 41: 397-404

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : uterine endometrium Other Data : 2010-12-17

CCSD : 29791

Title : Lysosphingolipids inhibit protein kinase C: implications for the sphingolipidoses

Authors : Hannun YA; Bell RM

Info : Science (1987) 235: 670-674

Other Data : 2010-12-17

CCSD : 32070

Title : The ganglioside GD1.alpha., IV3Neu5Ac,III6Neu5Ac-GgOse4Cer, is a major disialoganglioside in the highly metastatic murine lymphoreticular tumour cell line MDAY-D2

Authors : Muething J; Peter-Katalinic J; Hanisch FG; Unland F; Lehmann J

Info : Glycoconj J (1994) 11: 153-162

TAXID : 10090 Other Data : lymphoreticular tumor Other Data : 2010-12-17

CCSD : 33627

Title : In vitro synthesis of disialoganglioside (GD1.alpha.) from asialo-GM1 using sialyltransferases in rat liver vesicles

Authors : Hidari KI-PJ; Kawashima I; Tai T; Inagaki F; Nagai Y; Sanai Y

Info : Eur J Biochem (1994) 221: 603-609

Other Data : 2010-12-17

CCSD : 36453

Title : Gangliosides: Differentiation markers for murine T helper lymphocyte subpopulations TH1 and TH2

Authors : Ebel F; Schmitt E; Peter-Katalinic J; Kniep B; Muehlradt PF

Info : Biochemistry (1992) 31: 12190-12197

TAXID : 10090 Other Data : T helper cells Other Data : cell line:TH1, TH2 Other Data : 2010-12-17

CCSD : 36493

Title : Structural characterization of gangliosides from resting and endotoxin-stimulated murine B lymphocytes

Authors : Poertner A; Peter-Katalinic J; Brade H; Unland F; Buentemeyer H; Muething J

Info : Biochemistry (1993) 32: 12685-12693

TAXID : 10090 Other Data : B-cells Other Data : 2010-12-17

CCSD : 36574

Title : Glycosphingolipids of rat T cells. Predominance of asialo-GM1 and GD1c

Authors : Nohara K; Nakauchi H; Spiegel S

Info : Biochemistry (1994) 33: 4661-4666

TAXID : 10116 Other Data : T-cells, B-cells Other Data : 2010-12-17

CCSD : 38676

Title : Purification and characterization of sialidase L, a NeuAc.alpha.2-3-Gal- specific sialidase

Authors : Chou MY; Li SC; Kiso M; Hasegawa A; Li YT

Info : J Biol Chem (1994) 269: 18821-18826

Other Data : 2010-12-17

CCSD : 39530

Title : Characteristic expression of GD1.alpha.-ganglioside during lactation in murine mammary gland

Authors : Momoeda M; Momoeda K; Takamizawa K; Matsuzawa A; Hanaoka K; Taketani Y; Iwamori M

Info : Biochim Biophys Acta (1995) 1256: 151-156

TAXID : 10090 Other Data : mammary gland Other Data : 2010-12-17

CCSD : 40751

Title : Fluctuations in levels of various gangliosides in the different tracts of the oviduct of the frog (Rana esculenta) during the reproductive cycle

Authors : Giuliani A; Calappi E; Baldoni E; Bolognani L; Vitaioli L

Info : Ital J Biochem (1995) 44: 75-88

TAXID : 8401 Other Data : oviduct Other Data : 2010-12-17

CCSD : 44832

Title : The chemical constitution of gangliosides of the vertebrate nervous system

Authors : Wiegandt H

Info : Behav Brain Res (1995) 66: 85-97

Other Data : brain Other Data : 2010-12-17

CCSD : 44964

Title : .beta.1-4N-acetylgalactosaminyltransferase can synthesize both asialo- glycosphingolipid GM2 and glycosphingolipid GM2 in vitro and in vivo: isolation and characterization of a .beta.1-4N-acetylgalactosaminyltransferase cDNA clone from rat ascites hepatoma cell line AH7974F

Authors : Hidari KI-PJ; Ichikawa S; Furukawa K; Yamasaki M; Hirabayashi Y

Info : Biochem J (1994) 303: 957-965

TAXID : 10116 Other Data : testes Other Data : 2010-12-17

CCSD : 45377

Title : Methylation analysis of complex carbohydrates: Overview and critical comments

Authors : Hanisch FG

Info : Biol Mass Spectrom (1994) 23: 309-312

Other Data : 2010-12-17

CCSD : 47178

Title : Structural studies of gangliosides from the YAC-1 mouse lymphoma cell line by immunological detection and fast atom bombardment mass spectrometry

Authors : Muething J; Peter-Katalinic J; Hanisch FG; Neumann U

Info : Glycoconj J (1991) 8: 414-423

TAXID : 10090 Other Data : lymphocyte, T cells Other Data : 2010-12-17

CCSD : 47885

Title : Ganglioside GD1.alpha. in cerebellar Purkinje cells; Its specific absence in mouse mutants with Purkinje cell abnormality and altered immunoreactivity in response to conjunctive stimuli causing long term desensitization

Authors : Furuya S; Irie F; Hashikawa T; Nakazawa K; Kozakai A; Hasegawa A; Sudo K; Hirabayashi Y

Info : J Biol Chem (1994) 269: 32418-32425

TAXID : 10116 Other Data : brain Other Data : 2010-12-17

CCSD : 47926

Title : Preparation and antitus restricted to CD4+ T cells producing interleukin-2 and a small population of mature thymocytes in mice

Authors : Usui S; Murashima K; Sakai M; Kiho T; Ukai S

Info : J Biol Chem (1995) 270: 3876-3881

TAXID : 10090 Other Data : thymus, thymocyte Other Data : 2010-12-17

CCSD : 48581

Title : Ganglioside biosynthesis in mouse embryos: sialyltransferase IV and the asialo pathway

Authors : Seyfried TN; Novikov AM; Irvine RA; Brigande JV

Info : J Lipid Res (1994) 35: 993-1001

Other Data : 2010-12-17

JCGGDB ID JCGG-STR014560

Glycan Information

External Links