JCGG-STR004466:JCGGDB ID

JCGGDB Glycan Structure Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST)

JCGGDB ID JCGG-STR004466

GlyTouCan G18625KA

version 2

Glycan Information

Glyco Tree get Image

Composition

Hex 3 HexNAc 1 Neu5Ac 4
Mass Value Search

Gal 2 GalNAc 1 Glc 1 Neu5Ac 4
Structural Isomer Search

Descriptors Computed from Structure

InChIKey	OSJKIOJNKRDAKQ-UUEDUGPRSA-N
InChI	InChI=1S/C70H113N5O53/c1-18(84)71-35-23(89)6-67(63(106)107,123-53(35)40(95)27(93)10-76)121-31(14-80)44(99)55-37(73-20(3)86)25(91)8-69(125-55,65(110)111)127-57-43(98)30(13-79)116-61(48(57)103)120-52-39(75-22(5)88)60(115-29(12-78)42(52)97)119-51-34(17-83)117-62(118-50-33(16-82)114-59(105)47(102)46(50)101)49(104)58(51)128-70(66(112)113)9-26(92)38(74-21(4)87)56(126-70)45(100)32(15-81)122-68(64(108)109)7-24(90)36(72-19(2)85)54(124-68)41(96)28(94)11-77/h23-62,76-83,89-105H,6-17H2,1-5H3,(H,71,84)(H,72,85)(H,73,86)(H,74,87)(H,75,88)(H,106,107)(H,108,109)(H,110,111)(H,112,113)/t23-,24-,25-,26-,27+,28+,29+,30+,31+,32+,33+,34+,35+,36+,37+,38+,39+,40+,41+,42-,43-,44+,45+,46+,47+,48+,49+,50+,51-,52+,53+,54+,55+,56+,57-,58+,59+,60-,61-,62-,67+,68+,69-,70-/m0/s
SMILES	CC(=O)N[C@@H]1[C@@H](O)C[C@@](O[C@H](CO)[C@@H](O)[C@@H]2O[C@@](C[C@H](O)[C@H]2NC(C)=O)(O[C@H]2[C@@H](O)[C@@H](CO)O[C@@H](O[C@H]3[C@@H](O)[C@@H](CO)O[C@@H](O[C@H]4[C@@H](CO)O[C@@H](O[C@@H]5[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O[C@@]4(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O4)[C@H](O)[C@@H](CO)O[C@@]4(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O4)[C@H](O)[C@H](O)CO)C(O)=O)C(O)=O)[C@@H]3NC(C)=O)[C@@H]2O)C(O)=O)(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O

Mass

	Monoisotopic Mass	Average Mass
Underivatised Oligosaccharides	1871.6299	1872.6689
Permethylated Oligosaccharides	2348.1624	2349.5828
Peracetylated Oligosaccharides	2921.894	2923.6011

Glycan Motifs

Motif ID	Structure / SubStructure Name	Note
JCGG-MOTIF3003	ganglio	Reducing Terminal
JCGG-MOTIF4056	GQ1b
JCGG-MOTIF4120	Sia(a2-8)Sia(2-3)Gal / Terminal Disialyl Sequence	NON-Reducing Terminal

Chemical Synthesis

External Links

GlycoEpitope (Antiglycan Antibody)

GlycoEpitope GLPD-000059 GLPD-000059

Name:   GQ1b
Description:   IV³(Neu5Ac)₂II³(Neu5Ac)₂ Gg₄Cer
Reducing terminal:   (b-1)Cer

GMDB (MSⁿ)

GMDB OLG-0000fe

JCGG	JCGG JGD-000608 JGD-000608 Reducing terminal: (b-1)Cer

LipidBank (Spectral Data)

LipidBank GSG1106 GSG1106

Description: NeuAca2-8NeuAca2-3Galb1-3GalNAcb1-4(NeuAca2-8NeuAca2-3)Galb1-4GlcCer
Reducing terminal: (b-)Cer

GlycomeDB (Structure)

GlycomeDB 141 141

KEGG (Structure)

KEGG G00117 G00117

PACDB(Pathogen adhesion)

Pathogen:	Vibrio cholerae
Glycan Name:	GQ1b [ Not Binding]

Pathogen:	Escherichia coli
Glycan Name:	GQ1b [ Not Binding]

Pathogen:	Clostridium tetani
Glycan Name:	GQ1b [ Binding]

Pathogen:	Influenza virus (A/PR/8/34; H1N1; human)
Glycan Name:	GQ1b [ Not Binding]

Pathogen:	Influenza virus (B/Lee/40; human)
Glycan Name:	GQ1b [ Not Binding]

Pathogen:	Influenza virus (C/Ann Arbor/1/50; human)
Glycan Name:	GQ1b [ Not Binding]

Pathogen:	Escherichia coli (HB101(pCP3727))
Glycan Name:	GQ1b [ Binding]

Pathogen:	Yersinia pestis (pH6 antigen from Escherichia coli(HB101))
Glycan Name:	GQ1b [ Not Binding]

Pathogen:	Escherichia coli (HB101(pDG1))
Glycan Name:	GQ1b [ Not Binding]

Pathogen:	Rotavirus (Neuraminidase-sensitive; simian:SA11(P2/G3) / bovine:NCDV(P1/G6))
Glycan Name:	GQ1b [ Not Binding]

Pathogen:	Lactobacillus casei (IFO 3425)
Glycan Name:	GQ1b [ Not Binding]

CarbBank

CCSD : 1523

Title : The structure of the tetrasialoganglioside from human brain

Authors : Fredman P; Mansson JE; Svennerholm L; Karlsson KA; Pascher I; Samuelsson BE

Info : FEBS Lett (1980) 110: 80-84

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : brain Other Data : 2010-12-17

CCSD : 1524

Title : Isolation and characterization of two isomers of brain tetrasialogangliosides

Authors : Ando S; Yu RK

Info : J Biol Chem (1979) 254: 12224-12229

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : brain Other Data : 2010-12-17

CCSD : 3689

Title : Nondestructive detection of gangliosides with lipophilic fluorochromes and their employment for preparative high-performance thin- layer chromatography

Authors : Muthing J; Heitmann D

Info : Anal Biochem (1993) 208: 121-124

Other Data : 2010-12-17

CCSD : 5216

Title : Serum IgG antibody to ganglioside GQ1b is a possible marker of miller fisher syndrome

Authors : Chiba A; Kusunoki S; Shimizu T; Kanazawa I

Info : Ann Neurol (1992) 31: 677-679

Other Data : 2010-12-17

CCSD : 6971

Title : Molecular cloning and function analysis of sialyltranferase

Authors : Tsuji S

Info : J Biochem (1996) 120: 1-13

Other Data : 2010-12-17

CCSD : 9328

Title : Differential expression of gangliosides and galactolipids in fetal human oligodendrocytes and astrocytes in culture

Authors : Satoh J; Tai T; Kim SU

Info : Dev Brain Res (1996) 93: 172-181

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : GalC+ oligodendrocytes, GFAP+ astrocytes Other Data : 2010-12-17

CCSD : 9851

Title : Negative-ion fast atom bombardment and electrospray ionization tandem mass spectrometry for characterization of sulfated and sialyl Lewis-type glycosphingolipids

Authors : Ii T; Ohashi Y; Nagai Y

Info : Glycoconj J (1996) 13: 273-283

TAXID : 9913 Other Data : brain Other Data : 2010-12-17

CCSD : 11390

Title : A novel enzyme that cleaves the N-acyl linkage of ceramides in various glycosphingolipids as well as sphingomyelin to produce their lyso forms

Authors : Ito M; Kurita T; Kita K

Info : J Biol Chem (1995) 270: 24370-24374

Other Data : 2010-12-17

CCSD : 12993

Title : Variability in brain ganglioside content and composition of endothermic mammals, heterothermic hibernators and ectothermic fishes

Authors : Kappel T; Hilbig R; Rahmann H

Info : Neurochem Int (1993) 22: 555-566

Other Data : 2010-12-17

CCSD : 14415

Title : Bioactive gangliosides: analysis of functional structures of the tetrasialoganglioside GQ1b which promotes neurite outgrowth

Authors : Nakajima J; Tsuji S; Nagai Y

Info : Biochim Biophys Acta (1986) 876: 65-71

Other Data : 2010-12-17

CCSD : 14456

Title : Gangliosides and neutral glycosphingolipids of normal tissue and oat cell carcinoma of human lung

Authors : Hanqing M; Avrova N; Mansson JE; Molin K; Svennerholm L

Info : Biochim Biophys Acta (1986) 878: 360-370

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : lung Other Data : 2010-12-17

CCSD : 16082

Title : Different fine binding specificities of monoclonal antibodies to disialosylganglioside GD2

Authors : Tai T; Kawashima I; Tada N; Dairiki K

Info : J Biochem (1988) 103: 682-687

Other Data : 2010-12-17

CCSD : 18911

Title : Human brain gangliosides: developmental changes from early fetal stage to advanced age

Authors : Svennerholm L; Bostroem K; Fredman P; Maansson JE; Rosengren B; Rynmark BM

Info : Biochim Biophys Acta (1989) 1005: 109-117

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : brain Other Data : 2010-12-17

CCSD : 20287

Title : Bioactive ganglioside-mediated carbohydrate recognition in coupling with ecto-protein phosphorylation

Authors : Nagai Y; Tsuji S

Info : Ciba Found Symp (1989) 145: 119-134

Other Data : 2010-12-17

CCSD : 20654

Title : The pH-dependent changes of ganglioside biosynthesis in neuronal cell culture

Authors : Iber H; van Echten G; Klein RA; Sandhoff K

Info : Eur J Cell Biol (1990) 52: 236-240

Other Data : 2010-12-17

CCSD : 20716

Title : Use of gangliosides in the treatment of autonomic dysfunction in Chagas disease

Authors : Della Valle F; Iosa DJ

Info : Eur Pat Appl (1990) : 1-12

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : brain Other Data : 2010-12-17

CCSD : 21803

Title : Genetic polymorphism of rat liver gangliosides

Authors : Bouhours D; Bouhours JF

Info : J Biol Chem (1991) 266: 12944-12948

TAXID : 10116 Other Data : liver Other Data : 2010-12-17

CCSD : 22022

Title : Determination of gangliosides in human cerebrospinal fluid by high- performance thin-layer chromatography and direct densitometry

Authors : Trbojevic-Cepe M; Kracun I

Info : J Clin Chem Clin Biochem (1990) 28: 863-872

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : cerebrospinal fluid Other Data : 2010-12-17

CCSD : 22200

Title : Determination of gangliosides in six human primary medulloblastomas

Authors : Gottfries J; Fredman P; Maansson JE; Collins VP; Von Holst H; Armstrong DD; Percy AK; Wikstrand CJ; Bigner DD; Svennerholm L

Info : J Neurochem (1990) 55: 1322-1326

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : 2010-12-17

CCSD : 22217

Title : Gangliosides in human fetal brain

Authors : Svennerholm L; Rynmark BM; Vilbergsson G; Fredman P; Gottfries J; Maansson JE; Percy A

Info : J Neurochem (1991) 56: 1763-1768

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : brain Other Data : 2010-12-17

CCSD : 22644

Title : Rat dorsal root ganglion gangliosides during early development until senescence

Authors : Ohsawa T

Info : Mech Ageing Dev (1990) 53: 259-266

Other Data : 2010-12-17

CCSD : 22665

Title : Gangliosides in the brain in adult Down's syndrome and Alzheimer's disease

Authors : Brooksbank BWL; McGovern J

Info : Mol Chem Neuropathol (1989) 11: 143-156

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : brain Other Data : 2010-12-17

CCSD : 22725

Title : Patterns of endogenous gangliosides and metabolic processing of exogenous gangliosides in cerebellar granule cells during differentiation in culture

Authors : Riboni L; Prinetti A; Pitto M; Tettamanti G

Info : Neurochem Res (1990) 15: 1175-1183

Other Data : brain Other Data : 2010-12-17

CCSD : 23844

Title : Glycosphingolipids of human plasma

Authors : Kundu SK; Diego I; Osovitz S; Marcus DM

Info : Arch Biochem Biophys (1985) 238: 388-400

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : plasma Other Data : 2010-12-17

CCSD : 23866

Title : Monoclonal antibody R24 distinguishes between different N-acetyl-and N-glycolylneuraminic acid derivatives of ganglioside GD3

Authors : Tai T; Kawashima I; Furukawa K; Lloyd KO

Info : Arch Biochem Biophys (1988) 260: 51-55

Other Data : 2010-12-17

CCSD : 24825

Title : Analysis of gangliosides using fast atom bombardment mass spectrometry

Authors : Egge H; Peter-Katalinic J; Reuter G; Schauer R; Ghidoni R; Sonnino S; Tettamanti G

Info : Chem Phys Lipids (1985) 37: 127-141

Other Data : 2010-12-17

CCSD : 24826

Title : 2,4-Dinitrophenylhydrazides of polysialogangliosides

Authors : Tanaka T; Miyazaki K; Kishimoto Y; Stoskopf M; Kan LS; Demirev P; Fenselau C; Ando S

Info : Chem Phys Lipids (1988) 48: 261-266

Other Data : 2010-12-17

CCSD : 25288

Title : Analysis of autoantibodies to glycolipids on thymocytes in New Zealand Black mice

Authors : Ishii N; Watanabe K

Info : Immunology (1989) 68: 215-220

TAXID : 10090 Other Data : 2010-12-17

CCSD : 25360

Title : Correlation between ganglioside distribution and histological grading of human astrocytomas

Authors : Berra B; Gaini SM; Riboni L

Info : Int J Cancer (1985) 36: 363-366

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : 2010-12-17

CCSD : 25414

Title : Uncoupling of intracellular cyclic AMP and dome formation in cultured canine kidney epithelial cells: effects of gangliosides and vasopressin

Authors : Rodrig N; Osanai T; Iwamori M; Nagai Y

Info : J Biochem (1988) 104: 215-219

TAXID : 9913 Other Data : brain Other Data : 2010-12-17

CCSD : 25788

Title : Gangliosides and sulfatide in human cerebrospinal fluid: quantitation with immunoaffinity techniques

Authors : Davidsson P; Fredman P; Svennerholm L

Info : J Chromatogr (1989) 496: 279-289

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : cerebrospinal fluid Other Data : 2010-12-17

CCSD : 25929

Title : Ganglioside composition of normal and mutant mouse embryos

Authors : Bouvier JD; Seyfried TN

Info : J Neurochem (1989) 52: 460-466

TAXID : 10090 Other Data : neural tube Other Data : 2010-12-17

CCSD : 25943

Title : Lysosulfatide (galactosylsphingosine-3-O-sulfate) from metachromatic leukodystrophy and normal human brain

Authors : Rosengren B; Fredman P; Maansson JE; Svennerholm L

Info : J Neurochem (1989) 52: 1035-1041

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : brain Other Data : 2010-12-17

CCSD : 25952

Title : Further studies on the changes of chicken brain gangliosides during prenatal and postnatal life

Authors : Sonnino S; Bassi R; Chigorno V; Tettamanti G

Info : J Neurochem (1990) 54: 1653-1660

TAXID : 9031 Other Data : brain Other Data : 2010-12-17

CCSD : 25992

Title : Cerebellar ganglioside abnormalities in pcd mutant mice

Authors : Seyfried TN; Yu RK

Info : J Neurosci Res (1990) 26: 105-111

TAXID : 10090 Other Data : Purkinje cells Other Data : 2010-12-17

CCSD : 26272

Title : High-performance liquid affinity chromatography and in situ fluorescent labeling on thin-layer chromatography of glycosphingolipids

Authors : Tomono Y; Abe K; Watanabe K

Info : Anal Biochem (1990) 184: 360-368

Other Data : 2010-12-17

CCSD : 26342

Title : Detection of gangliosides by direct binding of Limax flavus agglutinin to thin layer chromatograms

Authors : Kielczynski W; Harrison LC

Info : Glycoconj J (1990) 7: 75-84

Other Data : 2010-12-17

CCSD : 27253

Title : Differences in lipid composition between isolated growth cones from the forebrain and those from the brainstem in the fetal rat

Authors : Igarashi M; Waki H; Hirota M; Hirabayashi Y; Obata K; Ando S

Info : Dev Brain Res (1990) 51: 1-9

TAXID : 10116 Other Data : brain Other Data : 2010-12-17

CCSD : 27480

Title : Differential distribution of major gangliosides in rat central nervous system detected by specific monoclonal antibodies

Authors : Kotani M; Kawashima I; Ozawa H; Terashima T; Tai T

Info : Glycobiology (1993) 3: 137-146

TAXID : 10116 Other Data : brain Other Data : 2010-12-17

CCSD : 27839

Title : Identification of disialosyl paragloboside and O-acetyldisialosyl paragloboside in cerebellum and embryonic cerebrum

Authors : Chou DKH; Flores S; Jungalwala FB

Info : J Neurochem (1990) 54: 1598-1607

Other Data : cerebellum Other Data : 2010-12-17

CCSD : 28949

Title : Recognition by two-dimensional thin-layer chromatography and densitometric quantification of alkali-labile gangliosides from the brain of different animals

Authors : Sonnino S; Ghidoni R; Chigorno V; Masserini M; Tettamanti G

Info : Anal Biochem (1983) 128: 104-114

Other Data : brain Other Data : 2010-12-17

CCSD : 29153

Title : Ganglioside-binding proteins in skeletal and cardiac muscle

Authors : Chan KFJ; Liu Y

Info : Glycobiology (1991) 1: 193-203

Other Data : 2010-12-17

CCSD : 29967

Title : Biosynthesis and excretion of gangliosides by the isolated perfused rat liver

Authors : Senn HJ; Sellin S; Fitzke E; Stehle T; Haussinger D; Wieland H; Gerok W

Info : Eur J Biochem (1992) 205: 809-814

TAXID : 10116 Other Data : liver Other Data : 2010-12-17

CCSD : 30113

Title : Specific ganglioside binding to receptor sites on T lymphocytes that couple to ganglioside-induced decrease of CD4 expression

Authors : Morrison WJ; Offner H; Vandenbark AA

Info : Life Sci (1989) 45: 1219-1226

Other Data : 2010-12-17

CCSD : 30923

Title : Ganglioside-specific binding protein on rat brain membranes

Authors : Tiemeyer M; Yasuda Y; Schnaar RL

Info : J Biol Chem (1989) 264: 1671-1681

Other Data : 2010-12-17

CCSD : 31404

Title : Synthetic studies on sialoglycoconjugates, Part 63. Total synthesis of ganglioside GQ1b

Authors : Ishida HK; Ishida H; Kiso M; Hasegawa A

Info : Carbohydr Res (1994) 260: C1-C6

Other Data : 2010-12-17

CCSD : 32691

Title : Generation of one set of monoclonal antibodies specific for a-pathway ganglio-series gangliosides

Authors : Kotani M; Ozawa H; Kawashima I; Ando S; Tai T

Info : Biochim Biophys Acta (1992) 1117: 97-103

Other Data : 2010-12-17

CCSD : 32706

Title : Immunosuppression by human gangliosides: I. Relationship of carbohydrate structure to the inhibition of T cell responses

Authors : Ladisch S; Becker H; Ulsh L

Info : Biochim Biophys Acta (1992) 1125: 180-188

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : brain Other Data : 2010-12-17

CCSD : 32724

Title : Solubilization and characterization of the acceptor for Clostridium botulinum type B neurotoxin from rat brain synaptic membranes

Authors : Nishiki TI; Ogasawara J; Kamata Y; Kozaki S

Info : Biochim Biophys Acta (1993) 1158: 333-338

Other Data : 2010-12-17

CCSD : 33249

Title : Purification and characterization of UDP-N-acetylgalactosamine GM3/GD3 N-acetylgalactosaminyltransferase from mouse liver

Authors : Hashimoto Y; Sekine M; Iwasaki K; Suzuki A

Info : J Biol Chem (1993) 268: 25857-25864

Other Data : 2010-12-17

CCSD : 33345

Title : Ganglioside distribution in the liver of inbred strains of rats and the cancerus liver of LEC rats

Authors : Kasai N; Kamimura A; Miyoshi I; Ariga T

Info : J Biochem (1993) 113: 251-257

TAXID : 10116 Other Data : liver Other Data : 2010-12-17

CCSD : 33687

Title : Substrate specificity of .alpha.2-3-sialyltransferases in ganglioside biosynthesis of rat liver golgi

Authors : Iber H; van Echten G; Sandhoff K

Info : Eur J Biochem (1991) 195: 115-120

Other Data : 2010-12-17

CCSD : 33948

Title : Purification and characterization of sialidase L, a NeuAc.alpha.2-3-Gal- specific sialidase

Authors : Chou MY; Li SC; Kiso M; Hasegawa A; Li YT

Info : J Biol Chem (1994) 269: 18821-18826

Other Data : 2010-12-17

CCSD : 34033

Title : Detection of complex gangliosides in human amniotic fluid

Authors : Rueda R; Tabsh K; Ladisch S

Info : FEBS Lett (1993) 328: 13-16

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : amnion Other Data : 2010-12-17

CCSD : 34107

Title : Generation of monoclonal antibodies specific for ganglioside lactone: Evidence of the expression of lactone on human melanoma cells

Authors : Kawashima I; Kotani M; Ozawa H; Suzuki M; Tai T

Info : Int J Cancer (1994) 58: 263-268

Other Data : 2010-12-17

CCSD : 34753

Title : Influence of glycosphingolipids on the release of histamine and sulfidopeptide leukotrienes from human basophils

Authors : Lichey J; Zuberbier T; Luck W; Lau S; Wahn U

Info : Int Arch Allergy Immunol (1994) 103: 252-259

Other Data : 2010-12-17

CCSD : 34760

Title : Gangliosides can activate human alternative complement pathway

Authors : Oshima H; Soma GI; Mizuno DI

Info : Int Immunol (1993) 5: 1349-1351

Other Data : 2010-12-17

CCSD : 34866

Title : Gangliosides as diagnostic markers of human astrocytomas and primitive neuroectodermal tumors

Authors : Sung CC; Pearl DK; Coons SW; Scheithauer BW; Johnson PC; Yates AJ

Info : Cancer (1994) 74: 3010-3022

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : brain Other Data : 2010-12-17

CCSD : 34889

Title : Antitumor effects of a novel monoclonal antibody with high binding affinity to ganglioside GD3

Authors : Ohta S; Honda A; Tokutake Y; Yoshida H; Hanai N

Info : Cancer Immunol Immunother (1993) 36: 260-266

Other Data : 2010-12-17

CCSD : 35165

Title : Adhesion of K99 fimbriated Escherichia coli to pig intestinal epithelium: correlation of adhesive and non-adhesive phenotypes with the sialoglycolipid content

Authors : Seignole D; Mouricout M; Duval-Iflah Y; Quintard B; Julien R

Info : J Gen Microbiol (1991) 137: 1591-1601

TAXID : 9823 Other Data : intestine brush border membrane Other Data : 2010-12-17

CCSD : 35260

Title : Identification and localization of the GM1 ganglioside in the cochlea using thin-layer chromatography and cholera toxin

Authors : Santi PA; Mancini P; Barnes C

Info : J Histochem Cytochem (1994) 42: 705-716

TAXID : 10152 Other Data : cochlea Other Data : 2010-12-17

CCSD : 35326

Title : Entry of newly synthesized gangliosides into myelin

Authors : Farrer RG; Benjamins JA

Info : J Neurochem (1992) 58: 1477-1484

TAXID : 10116 Other Data : brain Other Data : 2010-12-17

CCSD : 35333

Title : Neuronal ganglioside increases dependent on the neuron-Glia interaction in primary culture

Authors : Ogiso M; Ohta M; Harada Y; Hirano S

Info : J Neurochem (1992) 59: 636-643

TAXID : 10116 Other Data : neuron cells Other Data : 2010-12-17

CCSD : 35344

Title : Changes in the ganglioside long-chain base composition of rat cerebellar granule cells during differentiation and aging in culture

Authors : Valsecchi M; Palestini P; Chigorno V; Sonnino S; Tettamanti G

Info : J Neurochem (1993) 60: 193-196

TAXID : 10116 Other Data : brain, cerebellum, granule cells Other Data : 2010-12-17

CCSD : 35372

Title : Membrane lipids, selectively diminished in Alzheimer brains, suggest synapse loss as a primary event in early-onset form (type I) and demyelination in late-onset form (type II)

Authors : Svennerholm L; Gottfries CG

Info : J Neurochem (1994) 62: 1039-1047

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : 2010-12-17

CCSD : 35391

Title : Growth of ectopic dendrites on cortical pyramidal neurons in neuronal storage diseases correlates with abnormal accumulation of GM2 ganglioside

Authors : Siegel DA; Walkley SU

Info : J Neurochem (1994) 62: 1852-1862

TAXID : 9685 Other Data : brain Other Data : 2010-12-17

CCSD : 35404

Title : Activities of five different sialyltransferases in fish and rat brains

Authors : Freischutz B; Saito M; Rahmann H; Yu RK

Info : J Neurochem (1994) 62: 1965-1973

TAXID : 10116 Other Data : brain Other Data : 2010-12-17

CCSD : 35417

Title : Membrane lipids of adult human brain: Lipid composition of frontal and temporal lobe in subjects of age 20 to 100 years

Authors : Svennerholm L; Bostrom K; Jungbjer B; Olsson L

Info : J Neurochem (1994) 63: 1802-1811

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : brain Other Data : 2010-12-17

CCSD : 35446

Title : An immunologic abnormality common to Bickerstaff's brain stem encephalitis and Fisher's syndrome

Authors : Yuki N; Sato S; Tsuji S; Hozumi I; Miyatake T

Info : J Neurol Sci (1993) 118: 83-87

Other Data : 2010-12-17

CCSD : 35472

Title : Bimodal regulation of protein phosphorylation by a ganglioside in rat brain membrane

Authors : Nakaoka T; Tsuji S; Nagai Y

Info : J Neurosci Res (1992) 31: 724-730

Other Data : 2010-12-17

CCSD : 35481

Title : Neuronal cells mature faster on polyethyleneimine coated plates than on polylysine coated plates

Authors : Lelong IH; Petegnief V; Rebel G

Info : J Neurosci Res (1992) 32: 562-568

TAXID : 9031 Other Data : brain cells Other Data : 2010-12-17

CCSD : 35528

Title : Gangliosides and regeneration of the goldfish optic nerve in vivo and in vitro

Authors : Rahmann H; Rosner H; Sonnentag U; Esders S

Info : Neurochem Int (1992) 20: 371-383

TAXID : 7957 Other Data : retina, optic nerve Other Data : 2010-12-17

CCSD : 35536

Title : Gangliosides in the human brain development and aging

Authors : Kracun I; Rosner H; Drnovsek V; Vukelic Z; Cosovic C; Trbojevic-Cepe M; Kubat M

Info : Neurochem Int (1992) 20: 421-431

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : brain Other Data : 2010-12-17

CCSD : 35549

Title : A novel glycosignaling system: GQ1b-dependent neuritogenesis of human neuroblastoma cell line, goto, is closely associated with GQ1b-dependent ecto-type protein phosphorylation

Authors : Tsuji S; Yamashita T; Matsuda Y; Nagai Y

Info : Neurochem Int (1992) 21: 549-554

Other Data : 2010-12-17

CCSD : 35564

Title : Ganglioside and phospholipid composition of forebrain, cerebellum, and brain stem from adult and newborn rats

Authors : Cabezas JA; Andres R; Hueso P; Llanillo M; Martinez-Zorzano VS; Rodrigo M; Sanchez-Yague J

Info : Neurochem Res (1991) 16: 781-785

TAXID : 10116 Other Data : brain Other Data : 2010-12-17

CCSD : 35587

Title : Ganglioside composition changes in spongiform encephalopathies: Analyses of 263K scrapie-infected hamster brains

Authors : Di Martino A; Safar J; Callegaro L; Salem N; Gibbs CJ

Info : Neurochem Res (1993) 18: 907-913

Other Data : brain Other Data : 2010-12-17

CCSD : 35597

Title : Frequent presence of anti-GQ1b antibody in Fisher's syndrome

Authors : Yuki N; Sato S; Tsuji S; Ohsawa T; Miyatake T

Info : Neurology (1993) 43: 414-417

Other Data : 2010-12-17

CCSD : 35603

Title : Serum anti-GQ1b IgG antibody is associated with ophthalmoplegia in Miller Fisher syndrome and Guillain-Barre syndrome: Clinical and immunohistochemical studies

Authors : Chiba A; Kusunoki S; Obata H; Machinami R; Kanazawa I

Info : Neurology (1993) 43: 1911-1917

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : nerve, oculomotor, trochlear, abducens Other Data : 2010-12-17

CCSD : 35621

Title : Developmental changes of growth cone gangliosides of the postnatal rat cerebrum

Authors : Rosner H; Sonnentag U; Meiri K

Info : Neuroreport (1993) 4: 1207-1210

TAXID : 10116 Other Data : brain Other Data : 2010-12-17

CCSD : 35648

Title : Immunohistochemical demonstration of ganglioside GD3 in the central nervous system

Authors : Kawai K; Mori M; Watarai S; Yasuda T

Info : Neurosci Res (1994) 19: 119-124

Other Data : 2010-12-17

CCSD : 36133

Title : Gangliosides and modulation of the function of neural cells

Authors : Tettamanti G; Riboni L

Info : Adv Lipid Res (1993) 25: 235-267

Other Data : brain Other Data : 2010-12-17

CCSD : 36181

Title : Bioactive gangliosides: Differentiation inducers for hematopoietic cells and their mechanisms of actions

Authors : Saito M

Info : Adv Lipid Res (1993) 25: 303-327

Other Data : 2010-12-17

CCSD : 36395

Title : A novel ganglioside with a free amino group in bovine brain

Authors : Hidari KIPJ; Irie F; Suzuki M; Kon K; Ando S; Hirabayashi Y

Info : Biochem J (1993) 296: 259-263

TAXID : 9913 Other Data : brain Other Data : 2010-12-17

CCSD : 36842

Title : Improved separation of isomeric gangliosides by anion-exchange high- performance liquid chromatography

Authors : Muthing J; Unland F

Info : J Chromatogr B Biomed Sci App (1994) 658: 39-45

TAXID : 10090 Other Data : brain Other Data : 2010-12-17

CCSD : 36877

Title : Urinary bladder dysfunction in the BB/W diabetic rat: Effect of ganglioside treatment on functional and structural alterations

Authors : Paro M; Prashar A; Prosdocimi M; Cherian PV; Fiori MG; Sima AAF

Info : J Urol (1994) 151: 781-786

Other Data : 2010-12-17

CCSD : 37231

Title : Designation and schematic structure of gangliosides and allied glycosphingolipids

Authors : Svennerholm L

Info : Prog Brain Res (1994) 101: 11-14

Other Data : 2010-12-17

CCSD : 37254

Title : Receptors for cholera toxin and Escherichia coli heat-labile enterotoxin revisited

Authors : Holmgren J

Info : Prog Brain Res (1994) 101: 163-177

Other Data : 2010-12-17

CCSD : 37275

Title : Gangliosides and related glycoconjugates in myelin: relationship to peripheral neuropathies

Authors : Steck AJ; Burger D; Picasso S; Kuntzer T; Nardelli E; Schluep M

Info : Prog Brain Res (1994) 101: 305-312

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : peripheral nervous system Other Data : 2010-12-17

CCSD : 37482

Title : Immunorecognition of ganglioside epitopes: Correlation between affinity and cytotoxicity of ganglioside antibodies

Authors : Dippold W; Bernhard H

Info : Eur J Cancer (1992) 28A: 1605-1610

Other Data : 2010-12-17

CCSD : 38104

Title : Immunorecognition of different ganglioside epitopes on human normal and melanoma tissues

Authors : Bernhard H; Roth S; Bauerschmitz J; Meyer zum Buschenfelde K-H; Dippold W

Info : Int J Cancer (1992) 51: 568-572

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : 2010-12-17

CCSD : 38629

Title : Immunohistochemical localization of minor gangliosides in the rat central nervous system

Authors : Kotani M; Kawashima I; Ozawa H; Ogura K; Ishizuka I; Terashima T; Tai T

Info : Glycobiology (1994) 4: 855-865

TAXID : 10116 Other Data : brain, spinal cord Other Data : 2010-12-17

CCSD : 39368

Title : Immunohistochemical localization of major gangliosides in rat cerebellum

Authors : Kotani M; Kawashima I; Ozawa H; Terashima T; Tai T

Info : Proc Jpn Acad B (1992) 68: 109-113

TAXID : 10116 Other Data : cerebellum Other Data : 2010-12-17

CCSD : 39394

Title : A new type of two-dimensional thin-layer chromatography (TLC mapping) for analysis of acidic glycosphingolipid molecular species

Authors : Watanabe K; Nishiyama M

Info : Anal Biochem (1995) 227: 195-200

TAXID : 10116 Other Data : brain, liver, kidney Other Data : 2010-12-17

CCSD : 40333

Title : Phylogenetic conservation of ganglioside GD3 expression during early vertebrate ontogeny

Authors : Irvine RA; Seyfried TN

Info : Comp Biochem Physiol B Biochem Mol Biol (1994) 109: 603-612

TAXID : 10090 Other Data : brain Other Data : 2010-12-17

CCSD : 40739

Title : Circulating gangliosides of breast-cancer patients

Authors : Wiesner DA; Sweeley CC

Info : Int J Cancer (1995) 60: 294-299

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : serum Other Data : 2010-12-17

CCSD : 41133

Title : Improved thin-layer chromatographic separation of gangliosides by automated multiple development

Authors : Muthing J

Info : J Chromatogr B Biomed Sci App (1994) 657: 75-81

TAXID : 9031 Other Data : brain Other Data : 2010-12-17

CCSD : 41193

Title : Fisher's syndrome associated with chickenpox and anti-GQ1b antibody

Authors : Takano H; Yuki N

Info : J Neurol (1995) 242: 255-256

Other Data : 2010-12-17

CCSD : 41891

Title : Facile methods for isolation and determination of gangliosides in a small scale: Age-related changes of gangliosides in mouse brain synaptic plasma membranes

Authors : Waki H; Kon K; Tanaka Y; Ando S

Info : Anal Biochem (1994) 222: 156-162

Other Data : 2010-12-17

CCSD : 42083

Title : Serum anti-GQ1b IgG antibodies recognize surface epitopes on Campylobacter jejuni from patients with Miller Fisher syndrome

Authors : Jacobs BC; Endtz HP; van der Meche FGA; Hazenberg MP; Achtereekte HAM; van Doorn PA

Info : Ann Neurol (1995) 37: 260-264

TAXID : 197 Other Data : 2010-12-17

CCSD : 43347

Title : Successful plasmapheresis in Bickerstaff's brain stem encephalitis associated with anti-GQ1b antibody

Authors : Yuki N

Info : J Neurol Sci (1995) 131: 108-110

Other Data : 2010-12-17

CCSD : 43624

Title : Undernutrition alters the hypothalamic ganglioside profile of the fetal rat

Authors : Trindade VMT; Scotti L; Becker D; Perry MLS; Bernard EA

Info : Nutr Biochem (1995) 6: 155-157

TAXID : 10116 Other Data : hypothalmus Other Data : 2010-12-17

CCSD : 43829

Title : Pick's disease immunohistochemistry: New alterations and Alzheimer's disease comparisons

Authors : Yasuhara O; Matsuo A; Tooyama I; Kimura H; McGeer EG; McGeer PL

Info : Acta Neuropathol (1995) 89: 322-330

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : brain Other Data : 2010-12-17

CCSD : 44051

Title : Ganglioside metabolism- topology and regulation

Authors : Sandhoff K; van Echten G

Info : Adv Lipid Res (1993) 26: 119-142

Other Data : 2010-12-17

CCSD : 44078

Title : Molecular approaches to studying the intracellular trafficking of glycosphingolipids

Authors : Young WW

Info : Adv Lipid Res (1993) 26: 161-179

Other Data : 2010-12-17

CCSD : 44187

Title : Chronic ethanol effects on glycoconjugates and glycosyltransferases of rat brain

Authors : Omodeo-Sale F; Palestini P

Info : Alcohol (1994) 11: 301-306

TAXID : 10116 Other Data : brain Other Data : 2010-12-17

CCSD : 44196

Title : Ethanol attenuation of ganglioside sialylation and neuritogenesis

Authors : Rosenberg A; Noble EP

Info : Alcohol (1994) 11: 565-569

TAXID : 9031 Other Data : cultured brain neuron Other Data : 2010-12-17

CCSD : 44207

Title : Ganglioside GM1 reduces fetal alcohol effects in rat pups exposed to ethanol in utero

Authors : Hungund BL; Ross DC; Gokhale VS

Info : Alcohol Clin Exp Res (1994) 18: 1248-1251

TAXID : 10116 Other Data : brain Other Data : 2010-12-17

CCSD : 44845

Title : The chemical constitution of gangliosides of the vertebrate nervous system

Authors : Wiegandt H

Info : Behav Brain Res (1995) 66: 85-97

TAXID : 10116 Other Data : brain Other Data : 2010-12-17

CCSD : 44853

Title : Functional roles of gangliosides in bio-signaling

Authors : Nagai Y

Info : Behav Brain Res (1995) 66: 99-104

Other Data : 2010-12-17

CCSD : 44888

Title : Inhibition of neuritogenic ganglioside biosynthesis in chick brain neurons by calcium ionophore A23187

Authors : Rosenberg A; Noble EP

Info : Biochem Biophys Res Commun (1993) 190: 522-528

TAXID : 9031 Other Data : brain neuron cells Other Data : 2010-12-17

CCSD : 44889

Title : Protein kinase C-dependent expression of type I transglutaminase mRNA in ganglioside GQ1b- and calcium-stimulated human keratinocytes

Authors : Yada Y; Polakowska RR; Okano Y; Nozawa Y

Info : Biochem Biophys Res Commun (1993) 190: 688-694

Other Data : 2010-12-17

CCSD : 44903

Title : Interaction between ganglioside-containing liposome and rat T- lymphocyte: Confocal fluorescence microscopic study

Authors : Kato E; Akiyoshi K; Furuno T; Nakanishi M; Kikuchi A; Kataoka K; Sunamoto J

Info : Biochem Biophys Res Commun (1994) 203: 1750-1755

Other Data : 2010-12-17

CCSD : 45149

Title : Blood serum gangliosides and antibodies to gangliosides

Authors : Dyatlovitskaya EV

Info : Biochemistry (Mosc) (1992) 57: 689-693

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : blood serum Other Data : 2010-12-17

CCSD : 45162

Title : Ganglioside lactones

Authors : Dyatlovitskaya EV

Info : Biochemistry (Mosc) (1992) 57: 1005-1009

Other Data : 2010-12-17

CCSD : 45355

Title : Cocaine exposure induces changes in the ganglioside content of rat liver

Authors : Cabello J; Ruano MJ; Cabezas JA; Hueso P

Info : Biol Chem Hoppe-Seyler (1994) 375: 817-819

TAXID : 10116 Other Data : liver Other Data : 2010-12-17

CCSD : 45726

Title : Abnormality of cerebral gangliosides in Fukuyama type congenital muscular dystrophy

Authors : Izumi T; Hara K; Ogawa T; Osawa M; Saito K; Novo MdLP; Fukuyama Y; Takashima S

Info : Brain Dev (1995) 17: 33-37

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : brain Other Data : 2010-12-17

CCSD : 45855

Title : Correlation of ganglioside patterns of primary brain tumors with survival

Authors : Sung CC; Pearl DK; Coons SW; Scheithauer BW; Johnson PC; Zheng M; Yates AJ

Info : Cancer (1995) 75: 851-859

TAXID : 9606 Genus Species : man Scientific Name : Homo sapiens Other Data : brain Other Data : 2010-12-17

CCSD : 46255

Title : A comparative study on ceramide composition of cetacean brain gangliosides

Authors : Terabayashi T; Ogawa T; Kawanishi Y

Info : Comp Biochem Physiol B Biochem Mol Biol (1992) 103: 721-726

Other Data : brain Other Data : 2010-12-17

CCSD : 46273

Title : Influence of ambient temperature on content and composition of brain gangliosides in vertebrates

Authors : Becker K; Rahmann H

Info : Comp Biochem Physiol B Biochem Mol Biol (1995) 111: 299-310

TAXID : 40691 Other Data : brain Other Data : 2010-12-17

CCSD : 46539

Title : Lack of cell density-dependent changes in gangliosides of rat primary culture neurons

Authors : Ogiso M; Ohta M; Harada Y; Seki T; Hirano S

Info : Dev Neurosci (1992) 14: 247-255

TAXID : 10116 Other Data : brain, neuron cells Other Data : 2010-12-17

CCSD : 47576

Title : Bacteria of the human intestinal microbiota produce glycosidases specific for lacto-series glycosphingolipids

Authors : Falk P; Hoskins LC; Larson G

Info : J Biochem (1990) 108: 466-474

Other Data : 2010-12-17

CCSD : 47871

Title : Induction of cholinergic differentiation with neurite sprouting by de novo biosynthesis and expression of GD3 and b-series gangliosides in Neuro2a cells

Authors : Kojima N; Kurosawa N; Nishi T; Hanai N; Tsuji S

Info : J Biol Chem (1994) 269: 30701-30706

TAXID : 10090 Other Data : neuroblastoma Other Data : cell line:Neuro- 2a, N2a-GD3, N2a-bsr Other Data : 2010-12-17

CCSD : 47970

Title : Identification of gangliosides as inhibitors of ADP- ribosyltransferases of pertussis toxin and exoenzyme C3 from Clostridium botulinum

Authors : Hara-Yokoyama M; Hirabayashi Y; Irie F; Syuto B; Moriishi K; Sugiya H; Furuyama S

Info : J Biol Chem (1995) 270: 8115-8121

Other Data : 2010-12-17

CCSD : 49487

Title : The effects of diisopropylphosphorofluoridate (DFP) on the ganglioside profile in the chicken (Gallus domesticus) hindbrain

Authors : Bush DM; Lehning EJ; Bursian SJ

Info : Neurotoxicology (1995) 16: 55-61

TAXID : 9031 Other Data : brain Other Data : 2010-12-17

CCSD : 49537

Title : Pretreatment with gangliosides reduces abnormal nociceptive responses associated with a rodent peripheral mononeuropathy

Authors : Hayes RL; mao J; Price DD; Germano A; D'Avella D; Fiori M; Mayer DJ

Info : Pain (1992) 48: 391-396

Other Data : 2010-12-17

CCSD : 50128

Title : An alternative route of infection for viruses: Entry by means of the asialoglycoprotein receptor of a Sendai virus mutant lacking its attachment protein

Authors : Markwell MAK; Portner A; Schwartz AL

Info : Proc Natl Acad Sci U S A (1985) 82: 978-982

Other Data : cell line:MDBK, HeLa, MDCK Other Data : 2010-12-17

CCSD : 50181

Title : Polysialic acid engineering: Synthesis of polysialylated neoglycosphingolipids by using the polysialyltransferase from neuroinvasive Escherichia coli K1

Authors : Cho J; Troy FA

Info : Proc Natl Acad Sci U S A (1994) 91: 11427-11431

Other Data : 2010-12-17

CCSD : 50195

Title : Delineation and comparison of ganglioside-binding epitopes for the toxins of Vibrio cholerae, Escherichia coli, and Clostridium tetani: Evidence for overlapping epitopes

Authors : Angstrom J; Teneberg S; Karlsson K

Info : Proc Natl Acad Sci U S A (1994) 91: 11859-11863

Other Data : 2010-12-17

CCSD : 50219

Title : Development regulation of ganglioside metabolism

Authors : Yu RK

Info : Prog Brain Res (1994) 101: 31-44

TAXID : 10116 Other Data : brain Other Data : 2010-12-17

CCSD : 50268

Title : Gangliosides turnover and neural cells function: a new perspective

Authors : Tettamanti G; Riboni L

Info : Prog Brain Res (1994) 101: 77-100

Other Data : 2010-12-17