| JCEG ID |
Family |
Name |
Locus Tag |
Human Ortholog Name |
OMIM |
GWAS Catalog |
|
|
JCEG018
*
=
|
Core 1 GalT |
|
C38H2.2 |
C1GALT1
|
300611
300622
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| DOWNSTREAM |
|
0.0000002
(PCB105)
|
|
1.32
(unit decrease)
|
[0.83-1.81] |
25839716
|
|
Ng E 2015-04-02 Environ Res
Genome-wide association study of plasma levels of polychlorinated biphenyls disclose an association with the CYP2B6 gene in a population-based sample.
|
| MAPPED |
0.46 |
0.000004
|
|
|
[NR] |
19010793
|
|
Baranzini SE 2008-11-14 Hum Mol Genet
Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.
|
| MAPPED |
0.444 |
0.000001
|
|
0.099
(unit decrease)
|
[0.06-0.138] |
24159190
|
|
Seppala I 2013-10-24 Eur Heart J
Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.
|
| MAPPED |
0.444 |
0.0000006
|
|
0.101
(unit increase)
|
[0.062-0.14] |
24159190
|
|
Seppala I 2013-10-24 Eur Heart J
Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.
|
|
|
|
JCEG046
*
=
|
Fucosyltransferases |
pad-2 |
K10G9.3 |
POFUT2
|
610249
|
|
|
|
JCEG082
*
=
|
GlcNAcT(GnT) |
gly-13 |
B0416.6 |
MGAT1
|
160995
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| DOWNSTREAM |
0.85 |
0.000006
(females)
|
|
0.16
(kg decrease)
|
[NR] |
19851299
|
|
Johansson A 2009-10-22 Obesity (Silver Spring)
Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene.
|
| DOWNSTREAM |
0.85 |
0.00000007
(females)
|
|
2.96
(kg decrease)
|
[NR] |
19851299
|
|
Johansson A 2009-10-22 Obesity (Silver Spring)
Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene.
|
| MAPPED |
0.47 |
0.000005
(HDL-C)
|
|
0.23
(mg/dL increase)
|
[NR] |
19197348
|
|
Lowe JK 2009-02-06 PLoS Genet
Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.
|
| DOWNSTREAM |
0.14 |
0.000008
(EA-glucose response)
|
|
3.67
(mg/dL increase)
|
[2.06-5.28] |
23400010
|
|
Del-Aguila JL 2013-02-12 Pharmacogenomics J
Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.
|
|
|
|
JCEG089
*
=
|
GlcT |
cgt-2 |
F20B4.6 |
UGCG
|
602874
|
|
|
|
JCEG125
*
=
|
Glycosaminoglycan (GAG ) and Chitin synthesis genes |
sqv-5 |
T24D1.1 |
CHSY1 CHPF CHSY3 CHPF2 CSGALNACT1 CSGALNACT2
|
605282
608183
609963
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| MAPPED |
|
0.000007
|
|
0.226
(unit increase)
|
[NR] |
23322567
|
|
Lopes MC 2013-01-15 Invest Ophthalmol Vis Sci
Identification of a candidate gene for astigmatism.
|
| MAPPED |
|
0.0000002
|
2.14
|
|
[1.53-2.99] |
23726668
|
|
Hunter AM 2013-05-30 J Psychiatr Res
A genome-wide association study of a sustained pattern of antidepressant response.
|
| MAPPED |
0.66 |
0.000000002
|
|
0.08
(unit decrease)
|
[0.06-0.1] |
23291589
|
|
Lu Y 2013-01-06 Nat Genet
Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.
|
| MAPPED |
0.601 |
0.000001
|
|
0.022
(unit increase)
|
[NR] |
25201988
|
|
Rietveld CA 2014-09-08 Proc Natl Acad Sci U S A
Common genetic variants associated with cognitive performance identified using the proxy-phenotype method.
|
| UPSTREAM |
0.31 |
0.000002
(ETV6-RUNX1 positive)
|
1.19
|
|
[1.07 - 1.33] |
22076464
|
|
Ellinghaus E 2011-11-11 Leukemia
Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia.
|
| UPSTREAM |
0.31 |
0.000000006
(ETV6-RUNX1 positive, Northern European)
|
|
|
|
22076464
|
|
Ellinghaus E 2011-11-11 Leukemia
Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia.
|
|
|
|
JCEG126
*
=
|
Glycosaminoglycan (GAG ) and Chitin synthesis genes |
mig-22 |
PAR2.4 |
CHPF
|
608037
610405
|
|
|
|
JCEG131
*
=
|
Glycosyltransferase like (GTL) |
|
D2045.9 |
LHL1
|
|
|
|
|
JCEG150
*
=
|
PAPS synthase and PAPS transporters |
pst-2 |
F54E7.1 |
SLC35B3
|
610845
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| DOWNSTREAM |
|
0.000008
|
|
|
|
24324551
|
|
Deng X 2013-11-20 PLoS One
Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.
|
| DOWNSTREAM |
0.49 |
0.000003
(AA)
|
|
0.17
(unit decrease)
|
[0.092-0.248] |
23870195
|
|
Wojczynski MK 2013-07-19 BMC Med Genet
Genetics of coronary artery calcification among African Americans, a meta-analysis.
|
| DOWNSTREAM |
0.48 |
0.000000000000000003
|
|
0.046
(unit increase)
|
[0.035-0.056] |
25628336
|
|
Hromatka BS 2015-01-26 Hum Mol Genet
Genetic variants associated with motion sickness point to roles for inner ear development, neurological processes and glucose homeostasis.
|
|
|
|
JCEG155
*
=
|
POMT |
|
R12E2.13 |
POMT2
|
602934
607551
|
|
|
|
JCEG159
*
=
|
Sulfotransferase and sulfation-related genes |
hst-3.2 |
F52B10.2 |
HS3ST3A1 HS3ST3B1 HS3ST2 HS3ST4 HS3ST5 HS3ST6
|
604056
604057
604058
604059
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| MAPPED |
|
0.000002
|
|
|
|
24324551
|
|
Deng X 2013-11-20 PLoS One
Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.
|
| MAPPED |
|
0.0000007
|
|
0.0437
(unit increase)
|
[NR] |
24086445
|
|
Wang Q 2013-09-24 PLoS One
Genome-wide association analysis with gray matter volume as a quantitative phenotype in first-episode treatment-naïve patients with schizophrenia.
|
| MAPPED |
0.381 |
0.000004
(Dominant model)
|
1.647
|
|
[1.264-2.146] |
23648065
|
|
Low SK 2013-05-04 Cancer Sci
Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
|
| UPSTREAM |
0.2 |
0.000001
|
1.19
|
|
[NR] |
19525955
|
|
Bahlo 2009-06-14 Nat Genet
Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.
|
| DOWNSTREAM |
0.04 |
0.000002
|
0.082
|
|
(unit increase)] |
22823124
|
|
Verweij KJ 2012-07-24 Addict Biol
The genetic aetiology of cannabis use initiation: a meta-analysis of genome-wide association studies and a SNP-based heritability estimation.
|
|
|
|
JCEG217
*
=
|
ppGalNAcT |
gly-3 |
ZK688.8 |
GALNT1
|
602273
608369
|
|
|