| JCEG ID |
Family |
Name |
Locus Tag |
Human Ortholog Name |
OMIM |
GWAS Catalog |
|
|
JCEG018
*
=
|
Core 1 GalT |
|
C38H2.2 |
C1GALT1
|
300611
300622
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| DOWNSTREAM |
|
0.0000002
(PCB105)
|
|
1.32
(unit decrease)
|
[0.83-1.81] |
25839716
|
|
Ng E 2015-04-02 Environ Res
Genome-wide association study of plasma levels of polychlorinated biphenyls disclose an association with the CYP2B6 gene in a population-based sample.
|
| MAPPED |
0.46 |
0.000004
|
|
|
[NR] |
19010793
|
|
Baranzini SE 2008-11-14 Hum Mol Genet
Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.
|
| MAPPED |
0.444 |
0.000001
|
|
0.099
(unit decrease)
|
[0.06-0.138] |
24159190
|
|
Seppala I 2013-10-24 Eur Heart J
Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.
|
| MAPPED |
0.444 |
0.0000006
|
|
0.101
(unit increase)
|
[0.062-0.14] |
24159190
|
|
Seppala I 2013-10-24 Eur Heart J
Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.
|
|
|
|
JCEG019
*
=
|
Core 1 GalT |
|
C16D9.6 |
C1GALT1
|
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| DOWNSTREAM |
|
0.0000002
(PCB105)
|
|
1.32
(unit decrease)
|
[0.83-1.81] |
25839716
|
|
Ng E 2015-04-02 Environ Res
Genome-wide association study of plasma levels of polychlorinated biphenyls disclose an association with the CYP2B6 gene in a population-based sample.
|
| MAPPED |
0.46 |
0.000004
|
|
|
[NR] |
19010793
|
|
Baranzini SE 2008-11-14 Hum Mol Genet
Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.
|
| MAPPED |
0.444 |
0.000001
|
|
0.099
(unit decrease)
|
[0.06-0.138] |
24159190
|
|
Seppala I 2013-10-24 Eur Heart J
Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.
|
| MAPPED |
0.444 |
0.0000006
|
|
0.101
(unit increase)
|
[0.062-0.14] |
24159190
|
|
Seppala I 2013-10-24 Eur Heart J
Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.
|
|
|
|
JCEG049
*
=
|
Fucosyltransferases |
fut-3 |
F59E12.13 |
FUT5 FUT1 FUT10 FUT11
|
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| MAPPED |
|
0.0000000003
|
|
|
|
24941225
|
|
Liang Y 2014-06-18 PLoS One
Genetic variations affecting serum carcinoembryonic antigen levels and status of regional lymph nodes in patients with sporadic colorectal cancer from Southern China.
|
|
|
|
JCEG050
*
=
|
Fucosyltransferases |
fut-1 |
K08F8.3 |
FUT5 FUT3 FUT4 FUT6
|
104230
111100
111100
136835
136836
602030
606865
613852
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| DOWNSTREAM |
|
0.000004
(EA)
|
|
|
|
22566498
|
|
Turner ST 2012-05-07 Hypertension
Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.
|
| DOWNSTREAM |
|
0.0000009
(EA)
|
|
1.4
(unit increase)
|
[0.79-2.01] |
22566498
|
|
Turner ST 2012-05-07 Hypertension
Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.
|
| MAPPED |
|
0.00000003
|
|
|
|
24941225
|
|
Liang Y 2014-06-18 PLoS One
Genetic variations affecting serum carcinoembryonic antigen levels and status of regional lymph nodes in patients with sporadic colorectal cancer from Southern China.
|
| MAPPED |
|
0.0000000000004
|
|
49.78
(pg/ml increase)
|
[36.41-63.15] |
22367966
|
|
Lin X 2012-02-24 Hum Mol Genet
Genome-wide association study identifies novel loci associated with serum level of vitamin B12 in Chinese men.
|
| MAPPED |
|
0.0000000000000000008
|
|
|
|
24941225
|
|
Liang Y 2014-06-18 PLoS One
Genetic variations affecting serum carcinoembryonic antigen levels and status of regional lymph nodes in patients with sporadic colorectal cancer from Southern China.
|
| MAPPED |
0.38 |
(CA19-9)
|
|
0.282
(U/ml increase)
|
[0.20-0.37] |
23300138
|
|
He M 2013-01-07 Gut
A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.
|
| MAPPED |
0.33 |
0.00000000000000000000000000000000001
(CEA)
|
|
0.073
(ng/ml increase)
|
[0.048-0.098] |
23300138
|
|
He M 2013-01-07 Gut
A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.
|
| MAPPED |
0.33 |
(CA19-9)
|
|
0.481
(U/ml decrease)
|
[0.44-0.52] |
23300138
|
|
He M 2013-01-07 Gut
A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.
|
| MAPPED |
0.2 |
0.00000000000000000000000000000000000000000000000000000002
(CA19-9)
|
|
0.169
(U/ml decrease)
|
[0.11-0.22] |
23300138
|
|
He M 2013-01-07 Gut
A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.
|
| MAPPED |
0.11 |
0.0000000009
(DG12)
|
|
0.3
(unit decrease)
|
[0.20-0.40] |
21203500
|
|
Lauc G 2010-12-23 PLoS Genet
Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation.
|
| MAPPED |
0.11 |
0.000000000003
(DG7)
|
|
0.34
(unit decrease)
|
[0.24-0.44] |
21203500
|
|
Lauc G 2010-12-23 PLoS Genet
Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation.
|
| MAPPED |
0.11 |
0.000000000001
(FUC-A)
|
|
0.34
(unit decrease)
|
[0.24-0.44] |
21203500
|
|
Lauc G 2010-12-23 PLoS Genet
Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation.
|
| MAPPED |
0.11 |
0.00000000000000004
(DG9)
|
|
0.41
(unit decrease)
|
[0.31-0.51] |
21203500
|
|
Lauc G 2010-12-23 PLoS Genet
Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation.
|
|
|
|
JCEG079
*
|
GPI-anchor synthesis |
|
F49E7.2 |
PIGX
|
|
|
|
|
JCEG060
*
=
|
GPI-anchor synthesis |
|
F38E1.9 |
MPDU1
|
604041
609180
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| MAPPED |
0.29 |
0.00000001
(Testosterone)
|
|
0.28
(unit decrease)
|
[0.18-0.38] |
24049095
|
|
Chen Z 2013-09-18 J Med Genet
Genome-wide association study of sex hormones, gonadotropins and sex hormone-binding protein in Chinese men.
|
| MAPPED |
0.29 |
0.0000000000000000005
(SHBG)
|
|
0.09
(unit decrease)
|
[0.070-0.110] |
24049095
|
|
Chen Z 2013-09-18 J Med Genet
Genome-wide association study of sex hormones, gonadotropins and sex hormone-binding protein in Chinese men.
|
| MAPPED |
0.21 |
0.0000000004
|
1.23
|
|
[1.16-1.32] |
22197929
|
|
Yu XQ 2011-12-25 Nat Genet
A genome-wide association study in Han Chinese identifies multiple susceptibility loci for IgA nephropathy.
|
|
|
|
JCEG073
*
=
|
GPI-anchor synthesis |
|
F01G4.5 |
PIGQ
|
605754
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| UPSTREAM |
0.42 |
0.000009
|
|
0.1
(unit increase)
|
[0.059-0.141] |
22993228
|
|
Williams FM 2012-09-19 Ann Rheum Dis
Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects.
|
| MAPPED |
0.42 |
0.000004
|
|
0.11
(unit increase)
|
[0.065-0.155] |
22993228
|
|
Williams FM 2012-09-19 Ann Rheum Dis
Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects.
|
|
|
|
JCEG083
*
=
|
GlcNAcT(GnT) |
gly-12 |
F48E3.1 |
MGAT1
|
160995
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| DOWNSTREAM |
0.85 |
0.000006
(females)
|
|
0.16
(kg decrease)
|
[NR] |
19851299
|
|
Johansson A 2009-10-22 Obesity (Silver Spring)
Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene.
|
| DOWNSTREAM |
0.85 |
0.00000007
(females)
|
|
2.96
(kg decrease)
|
[NR] |
19851299
|
|
Johansson A 2009-10-22 Obesity (Silver Spring)
Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene.
|
| MAPPED |
0.47 |
0.000005
(HDL-C)
|
|
0.23
(mg/dL increase)
|
[NR] |
19197348
|
|
Lowe JK 2009-02-06 PLoS Genet
Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.
|
| DOWNSTREAM |
0.14 |
0.000008
(EA-glucose response)
|
|
3.67
(mg/dL increase)
|
[2.06-5.28] |
23400010
|
|
Del-Aguila JL 2013-02-12 Pharmacogenomics J
Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.
|
|
|
|
JCEG085
*
=
|
GlcNAcT(GnT) |
gly-2 |
C55B7.2 |
MGAT5 MGAT5B
|
601774
612441
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| DOWNSTREAM |
|
0.000008
(M)
|
|
17.78
(unit decrease)
|
[10.16-25.4] |
25524916
|
|
Palmer ND 2014-12-18 Diabetes
Genetic Variants Associated with Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium.
|
| DOWNSTREAM |
0.9858 |
0.000007
(Ordinal I)
|
|
2.5604
(unit increase)
|
[1.45-3.68] |
25188341
|
|
Beecham GW 2014-09-04 PLoS Genet
Genome-Wide Association Meta-analysis of Neuropathologic Features of Alzheimer's Disease and Related Dementias.
|
| UPSTREAM |
0.974 |
0.00000003
(Chinese)
|
|
0.328
(unit decrease)
|
[0.21-0.44] |
24383474
|
|
Manichaikul A 2014-01-02 Am J Respir Crit Care Med
Genome-wide study of percent emphysema on computed tomography in the general population. The Multi-Ethnic Study of Atherosclerosis Lung/SNP Health Association Resource Study.
|
| UPSTREAM |
0.917 |
0.000003
|
1.61
|
|
[1.32-2.0] |
22683750
|
|
Sinner MF 2012-06-06 Heart Rhythm
A meta-analysis of genome-wide association studies of the electrocardiographic early repolarization pattern.
|
| DOWNSTREAM |
0.8 |
0.000000000002
|
|
0.032
(unit decrease)
|
[NR] |
20881960
|
|
Lango Allen H 2010-09-29 Nature
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
|
| MAPPED |
0.64 |
0.000007
(overall)
|
|
|
|
22589738
|
|
Fox CS 2012-05-10 PLoS Genet
Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.
|
| MAPPED |
0.36 |
0.0000002
|
|
|
|
20117844
|
|
Brynedal B 2010-02-01 J Neuroimmunol
MGAT5 alters the severity of multiple sclerosis.
|
| DOWNSTREAM |
0.2 |
0.000003
(Recessive)
|
34
|
|
[4.29-269.48] |
22293537
|
|
Kiyotani K 2012-01-29 Pharmacogenet Genomics
A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy.
|
| UPSTREAM |
0.08 |
0.000005
|
0.069
|
|
(unit decrease)] |
22823124
|
|
Verweij KJ 2012-07-24 Addict Biol
The genetic aetiology of cannabis use initiation: a meta-analysis of genome-wide association studies and a SNP-based heritability estimation.
|
| DOWNSTREAM |
0.023 |
0.00000004
|
|
0.048
(unit decrease)
|
[0.031-0.065] |
23362303
|
|
Wu JH 2013-01-29 Circ Cardiovasc Genet
Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.
|
|
|
|
JCEG097
*
=
|
Glucuronyltransferase(GlcAT) |
sqv-8 |
ZK1307.5 |
B3GAT3 B3GAT2
|
151290
245600
606374
607497
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| UPSTREAM |
|
0.000005
|
0.2918
|
|
(unit increase)] |
23319000
|
|
Luykx JJ 2013-01-15 Mol Psychiatry
Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.
|
| MAPPED |
0.219 |
0.000007
(ALT/AST)
|
|
0.03
(unit increase)
|
[NR] |
23251661
|
|
Comuzzie AG 2012-12-04 PLoS One
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
|
| UPSTREAM |
0.16 |
0.0000009
|
|
1.17
(unit decrease)
|
[0.70-1.64] |
21326311
|
|
Bhatnagar P 2011-02-17 J Hum Genet
Genome-wide association study identifies genetic variants influencing F-cell levels in sickle-cell patients.
|
|
|
|
JCEG096
*
=
|
Glucuronyltransferase(GlcAT) |
glct-6 |
W07G9.2 |
B3GAT1
|
151290
245600
606374
607497
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| UPSTREAM |
|
0.000008
|
4.35
|
|
[2.28-8.30] |
24172245
|
|
Haga S 2013-10-31 J Hum Genet
A genome-wide association study of third molar agenesis in Japanese and Korean populations.
|
| MAPPED |
|
0.000003
|
0.701
|
|
(unit decrease)] |
24277619
|
|
Quillen EE 2013-11-26 Am J Med Genet B Neuropsychiatr Genet
ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.
|
| UPSTREAM |
|
0.000002
|
|
0.64
(unit increase)
|
[0.39-0.89] |
25562672
|
|
Byrne EM 2014-12-09 J Clin Psychiatry
Seasonality shows evidence for polygenic architecture and genetic correlation with schizophrenia and bipolar disorder.
|
| UPSTREAM |
0.889723713 |
0.000009
(IGP36)
|
|
0.227
(unit decrease)
|
[0.13-0.33] |
23382691
|
|
Lauc G 2013-01-31 PLoS Genet
Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
|
| UPSTREAM |
0.871 |
0.000002
|
|
|
[NR] |
23049088
|
|
Meng W 2012-10-09 Invest Ophthalmol Vis Sci
A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population.
|
| DOWNSTREAM |
0.53 |
0.000005
(CERAD-dr)
|
|
0.2826
(unit decrease)
|
[0.16-0.4] |
25648963
|
|
Debette S 2014-11-25 Biol Psychiatry
Genome-wide Studies of Verbal Declarative Memory in Nondemented Older People: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium.
|
| UPSTREAM |
0.143 |
0.0000007
|
|
|
[NR] |
23049088
|
|
Meng W 2012-10-09 Invest Ophthalmol Vis Sci
A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population.
|
|
|
|
JCEG117
|
Glyco_transf_92 |
|
Y105C5B.25 |
|
|
|
|
|
JCEG102
|
Glyco_transf_92 |
|
D1014.7 |
|
|
|
|
|
JCEG133
*
=
|
LARGE |
lge-1 |
K09C8.4 |
LARGE
|
603590
605517
608840
609709
613154
615287
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| DOWNSTREAM |
0.56 |
0.000006
(women)
|
|
|
|
22589738
|
|
Fox CS 2012-05-10 PLoS Genet
Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.
|
| DOWNSTREAM |
0.54 |
0.0000006
(women)
|
|
|
|
22589738
|
|
Fox CS 2012-05-10 PLoS Genet
Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.
|
| MAPPED |
0.28 |
0.000008
(overall)
|
|
|
|
22589738
|
|
Fox CS 2012-05-10 PLoS Genet
Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.
|
| MAPPED |
0.11 |
0.000008
|
1.44
|
|
[1.28-1.60] |
24962325
|
|
Kapoor M 2014-06-11 Drug Alcohol Depend
Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.
|
|
|
|
JCEG135
*
=
|
O-GlcNAcT |
ogt-1 |
K04G7.3 |
OGT
|
300255
|
|
|
|
JCEG151
*
=
|
PAPS synthase and PAPS transporters |
pps-1 |
T14G10.1 |
PAPSS1 PAPSS2
|
603005
603262
612847
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| MAPPED |
|
0.000004
|
1.32
|
|
[1.17-1.49] |
19727025
|
|
De Moor MH 2009-09-02 Med Sci Sports Exerc
Genome-wide association study of exercise behavior in Dutch and American adults.
|
| DOWNSTREAM |
|
0.000002
(EA)
|
0.02742
|
|
(0.01614-0.03871) (mg/dl increase)] |
25886283
|
|
Chang X 2015-04-17 PLoS One
Genome-wide association study of serum minerals levels in children of different ethnic background.
|
| DOWNSTREAM |
|
0.0000004
|
|
0.0243
(mg/dl increase)
|
[NR] |
25886283
|
|
Chang X 2015-04-17 PLoS One
Genome-wide association study of serum minerals levels in children of different ethnic background.
|
| DOWNSTREAM |
0.029 |
0.00000005
|
|
|
[NR] |
24478790
|
|
Lee JH 2014-01-17 Front Genet
Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study.
|
|
|
|
JCEG152
*
=
|
POFUT |
|
C15C7.7 |
POFUT1
|
607491
615327
|
|
|
|
JCEG161
*
=
|
Sulfotransferase and sulfation-related genes |
hst-1 |
F08B4.6 |
NDST1
|
600853
603268
603950
615039
|
|
|
|
JCEG157
*
=
|
Sulfotransferase and sulfation-related genes |
hst-2 |
C34F6.4 |
HS2ST1
|
604844
|
|
|
|
JCEG160
*
=
|
Sulfotransferase and sulfation-related genes |
hst-6 |
Y34B4A.3 |
HS6ST1
|
300545
604846
609401
614880
|
|
|
|
JCEG159
*
=
|
Sulfotransferase and sulfation-related genes |
hst-3.2 |
F52B10.2 |
HS3ST3A1 HS3ST3B1 HS3ST2 HS3ST4 HS3ST5 HS3ST6
|
604056
604057
604058
604059
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| MAPPED |
|
0.000002
|
|
|
|
24324551
|
|
Deng X 2013-11-20 PLoS One
Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.
|
| MAPPED |
|
0.0000007
|
|
0.0437
(unit increase)
|
[NR] |
24086445
|
|
Wang Q 2013-09-24 PLoS One
Genome-wide association analysis with gray matter volume as a quantitative phenotype in first-episode treatment-naïve patients with schizophrenia.
|
| MAPPED |
0.381 |
0.000004
(Dominant model)
|
1.647
|
|
[1.264-2.146] |
23648065
|
|
Low SK 2013-05-04 Cancer Sci
Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
|
| UPSTREAM |
0.2 |
0.000001
|
1.19
|
|
[NR] |
19525955
|
|
Bahlo 2009-06-14 Nat Genet
Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.
|
| DOWNSTREAM |
0.04 |
0.000002
|
0.082
|
|
(unit increase)] |
22823124
|
|
Verweij KJ 2012-07-24 Addict Biol
The genetic aetiology of cannabis use initiation: a meta-analysis of genome-wide association studies and a SNP-based heritability estimation.
|
|
|
|
JCEG165
*
=
|
UGCGL1 |
uggt-1 |
F48E3.3 |
UGGT1 UGGT2
|
605897
605898
|
|
|
|
JCEG167
*
=
|
a-N-acetylglucosaminidase |
|
K09E4.4 |
NAGLU
|
252920
609701
|
|
|
|
JCEG175
*
=
|
b3GalT1/b3GnT orthologs |
|
B0024.15 |
B3GALT1 B3GNT2 B3GNT5
|
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| MAPPED |
0.103 |
0.000002
(Amylin )
|
|
0.03
(pM increase)
|
[NR] |
23251661
|
|
Comuzzie AG 2012-12-04 PLoS One
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
|
| MAPPED |
0.083 |
0.000008
(Diet fat )
|
|
0.04
(%energy increase)
|
[NR] |
23251661
|
|
Comuzzie AG 2012-12-04 PLoS One
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
|
| DOWNSTREAM |
0.04 |
0.000000002
(KvDMR 21)
|
|
|
|
23725790
|
|
Renteria ME 2013-06-03 Twin Res Hum Genet
GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.
|
|
|
|
JCEG173
*
=
|
b3GalT1/b3GnT orthologs |
bre-2 |
Y39E4B.9 |
B3GALT1
|
603018
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| MAPPED |
0.103 |
0.000002
(Amylin )
|
|
0.03
(pM increase)
|
[NR] |
23251661
|
|
Comuzzie AG 2012-12-04 PLoS One
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
|
| MAPPED |
0.083 |
0.000008
(Diet fat )
|
|
0.04
(%energy increase)
|
[NR] |
23251661
|
|
Comuzzie AG 2012-12-04 PLoS One
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
|
| DOWNSTREAM |
0.04 |
0.000000002
(KvDMR 21)
|
|
|
|
23725790
|
|
Renteria ME 2013-06-03 Twin Res Hum Genet
GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.
|
|
|
|
JCEG203
*
=
|
b6GnT |
|
F30A10.4 |
GCNT4
|
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| DOWNSTREAM |
|
0.000004
|
0.0888
|
|
(unit increase)] |
23362303
|
|
Wu JH 2013-01-29 Circ Cardiovasc Genet
Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.
|
|
|
|
JCEG200
*
=
|
b6GnT |
|
T28F3.9 |
GCNT3
|
|
|
|
|
JCEG189
*
=
|
b6GnT |
gly-1 |
F44F4.6 |
GCNT1
|
|
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| DOWNSTREAM |
0.71 |
0.000007
|
1.56
|
|
[1.28-1.89] |
21546767
|
|
Murea M 2011-05-05 Am J Nephrol
Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes.
|
|
|
|
JCEG217
*
=
|
ppGalNAcT |
gly-3 |
ZK688.8 |
GALNT1
|
602273
608369
|
|
|