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Definition: "Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses." [ISBN:0140512888]
JCEG ID Family Name Locus Tag Human Ortholog Name OMIM GWAS Catalog
JCEG018 * = Core 1 GalT C38H2.2 C1GALT1 300611
300622
STREAMRAFp-valueORBETACIStudy
DOWNSTREAM 2.0E-7 (PCB105) 1.32 (unit decrease) [0.83-1.81] 25839716
MAPPED 0.46 4.0E-6 [NR] 19010793
MAPPED 0.444 1.0E-6 0.099 (unit decrease) [0.06-0.138] 24159190
MAPPED 0.444 6.0E-7 0.101 (unit increase) [0.062-0.14] 24159190
JCEG019 * = Core 1 GalT C16D9.6 C1GALT1
STREAMRAFp-valueORBETACIStudy
DOWNSTREAM 2.0E-7 (PCB105) 1.32 (unit decrease) [0.83-1.81] 25839716
MAPPED 0.46 4.0E-6 [NR] 19010793
MAPPED 0.444 1.0E-6 0.099 (unit decrease) [0.06-0.138] 24159190
MAPPED 0.444 6.0E-7 0.101 (unit increase) [0.062-0.14] 24159190
JCEG049 * = Fucosyltransferases fut-3 F59E12.13 FUT5 FUT1 FUT10 FUT11
STREAMRAFp-valueORBETACIStudy
MAPPED 3.0E-10 24941225
JCEG050 * = Fucosyltransferases fut-1 K08F8.3 FUT5 FUT3 FUT4 FUT6 104230
111100
111100
136835
136836
602030
606865
613852
STREAMRAFp-valueORBETACIStudy
DOWNSTREAM 4.0E-6 (EA) 22566498
DOWNSTREAM 9.0E-7 (EA) 1.4 (unit increase) [0.79-2.01] 22566498
MAPPED 3.0E-8 24941225
MAPPED 4.0E-13 49.78 (pg/ml increase) [36.41-63.15] 22367966
MAPPED 8.0E-19 24941225
MAPPED 0.38 (CA19-9) 0.282 (U/ml increase) [0.20-0.37] 23300138
MAPPED 0.33 1.0E-35 (CEA) 0.073 (ng/ml increase) [0.048-0.098] 23300138
MAPPED 0.33 (CA19-9) 0.481 (U/ml decrease) [0.44-0.52] 23300138
MAPPED 0.2 2.0E-56 (CA19-9) 0.169 (U/ml decrease) [0.11-0.22] 23300138
MAPPED 0.11 9.0E-10 (DG12) 0.3 (unit decrease) [0.20-0.40] 21203500
MAPPED 0.11 3.0E-12 (DG7) 0.34 (unit decrease) [0.24-0.44] 21203500
MAPPED 0.11 1.0E-12 (FUC-A) 0.34 (unit decrease) [0.24-0.44] 21203500
MAPPED 0.11 4.0E-17 (DG9) 0.41 (unit decrease) [0.31-0.51] 21203500
JCEG079 * GPI-anchor synthesis F49E7.2 PIGX
JCEG060 * = GPI-anchor synthesis F38E1.9 MPDU1 604041
609180
STREAMRAFp-valueORBETACIStudy
MAPPED 0.29 1.0E-8 (Testosterone) 0.28 (unit decrease) [0.18-0.38] 24049095
MAPPED 0.29 5.0E-19 (SHBG) 0.09 (unit decrease) [0.070-0.110] 24049095
MAPPED 0.21 4.0E-10 1.23 [1.16-1.32] 22197929
JCEG073 * = GPI-anchor synthesis F01G4.5 PIGQ 605754
STREAMRAFp-valueORBETACIStudy
UPSTREAM 0.42 9.0E-6 0.1 (unit increase) [0.059-0.141] 22993228
MAPPED 0.42 4.0E-6 0.11 (unit increase) [0.065-0.155] 22993228
JCEG083 * = GlcNAcT(GnT) gly-12 F48E3.1 MGAT1 160995
STREAMRAFp-valueORBETACIStudy
DOWNSTREAM 0.85 6.0E-6 (females) 0.16 (kg decrease) [NR] 19851299
DOWNSTREAM 0.85 7.0E-8 (females) 2.96 (kg decrease) [NR] 19851299
MAPPED 0.47 5.0E-6 (HDL-C) 0.23 (mg/dL increase) [NR] 19197348
DOWNSTREAM 0.14 8.0E-6 (EA-glucose response) 3.67 (mg/dL increase) [2.06-5.28] 23400010
JCEG085 * = GlcNAcT(GnT) gly-2 C55B7.2 MGAT5 MGAT5B 601774
612441
STREAMRAFp-valueORBETACIStudy
DOWNSTREAM 8.0E-6 (M) 17.78 (unit decrease) [10.16-25.4] 25524916
DOWNSTREAM 0.9858 7.0E-6 (Ordinal I) 2.5604 (unit increase) [1.45-3.68] 25188341
UPSTREAM 0.974 3.0E-8 (Chinese) 0.328 (unit decrease) [0.21-0.44] 24383474
UPSTREAM 0.917 3.0E-6 1.61 [1.32-2.0] 22683750
DOWNSTREAM 0.8 2.0E-12 0.032 (unit decrease) [NR] 20881960
MAPPED 0.64 7.0E-6 (overall) 22589738
MAPPED 0.36 2.0E-7 20117844
DOWNSTREAM 0.2 3.0E-6 (Recessive) 34.0 [4.29-269.48] 22293537
UPSTREAM 0.08 5.0E-6 0.069 (unit decrease)] 22823124
DOWNSTREAM 0.023 4.0E-8 0.048 (unit decrease) [0.031-0.065] 23362303
JCEG097 * = Glucuronyltransferase(GlcAT) sqv-8 ZK1307.5 B3GAT3 B3GAT2 151290
245600
606374
607497
STREAMRAFp-valueORBETACIStudy
UPSTREAM 5.0E-6 0.2918 (unit increase)] 23319000
MAPPED 0.219 7.0E-6 (ALT/AST) 0.03 (unit increase) [NR] 23251661
UPSTREAM 0.16 9.0E-7 1.17 (unit decrease) [0.70-1.64] 21326311
JCEG096 * = Glucuronyltransferase(GlcAT) glct-6 W07G9.2 B3GAT1 151290
245600
606374
607497
STREAMRAFp-valueORBETACIStudy
UPSTREAM 8.0E-6 4.35 [2.28-8.30] 24172245
MAPPED 3.0E-6 0.701 (unit decrease)] 24277619
UPSTREAM 2.0E-6 0.64 (unit increase) [0.39-0.89] 25562672
UPSTREAM 0.889723713 9.0E-6 (IGP36) 0.227 (unit decrease) [0.13-0.33] 23382691
UPSTREAM 0.871 2.0E-6 [NR] 23049088
DOWNSTREAM 0.53 5.0E-6 (CERAD-dr) 0.2826 (unit decrease) [0.16-0.4] 25648963
UPSTREAM 0.143 7.0E-7 [NR] 23049088
JCEG117 Glyco_transf_92 Y105C5B.25
JCEG102 Glyco_transf_92 D1014.7
JCEG133 * = LARGE lge-1 K09C8.4 LARGE 603590
605517
608840
609709
613154
615287
STREAMRAFp-valueORBETACIStudy
DOWNSTREAM 0.56 6.0E-6 (women) 22589738
DOWNSTREAM 0.54 6.0E-7 (women) 22589738
MAPPED 0.28 8.0E-6 (overall) 22589738
MAPPED 0.11 8.0E-6 1.44 [1.28-1.60] 24962325
JCEG135 * = O-GlcNAcT ogt-1 K04G7.3 OGT 300255
JCEG151 * = PAPS synthase and PAPS transporters pps-1 T14G10.1 PAPSS1 PAPSS2 603005
603262
612847
STREAMRAFp-valueORBETACIStudy
MAPPED 4.0E-6 1.32 [1.17-1.49] 19727025
DOWNSTREAM 2.0E-6 (EA) 0.02742 (0.01614-0.03871) (mg/dl increase)] 25886283
DOWNSTREAM 4.0E-7 0.0243 (mg/dl increase) [NR] 25886283
DOWNSTREAM 0.029 5.0E-8 [NR] 24478790
JCEG152 * = POFUT C15C7.7 POFUT1 607491
615327
JCEG161 * = Sulfotransferase and sulfation-related genes hst-1 F08B4.6 NDST1 600853
603268
603950
615039
JCEG157 * = Sulfotransferase and sulfation-related genes hst-2 C34F6.4 HS2ST1 604844
JCEG160 * = Sulfotransferase and sulfation-related genes hst-6 Y34B4A.3 HS6ST1 300545
604846
609401
614880
JCEG159 * = Sulfotransferase and sulfation-related genes hst-3.2 F52B10.2 HS3ST3A1 HS3ST3B1 HS3ST2 HS3ST4 HS3ST5 HS3ST6 604056
604057
604058
604059
STREAMRAFp-valueORBETACIStudy
MAPPED 2.0E-6 24324551
MAPPED 7.0E-7 0.0437 (unit increase) [NR] 24086445
MAPPED 0.381 4.0E-6 (Dominant model) 1.647 [1.264-2.146] 23648065
UPSTREAM 0.2 1.0E-6 1.19 [NR] 19525955
DOWNSTREAM 0.04 2.0E-6 0.082 (unit increase)] 22823124
JCEG165 * = UGCGL1 uggt-1 F48E3.3 UGGT1 UGGT2 605897
605898
JCEG167 * = a-N-acetylglucosaminidase K09E4.4 NAGLU 252920
609701
JCEG175 * = b3GalT1/b3GnT orthologs B0024.15 B3GALT1 B3GNT2 B3GNT5
STREAMRAFp-valueORBETACIStudy
MAPPED 0.103 2.0E-6 (Amylin ) 0.03 (pM increase) [NR] 23251661
MAPPED 0.083 8.0E-6 (Diet fat ) 0.04 (%energy increase) [NR] 23251661
DOWNSTREAM 0.04 2.0E-9 (KvDMR 21) 23725790
JCEG173 * = b3GalT1/b3GnT orthologs bre-2 Y39E4B.9 B3GALT1 603018
STREAMRAFp-valueORBETACIStudy
MAPPED 0.103 2.0E-6 (Amylin ) 0.03 (pM increase) [NR] 23251661
MAPPED 0.083 8.0E-6 (Diet fat ) 0.04 (%energy increase) [NR] 23251661
DOWNSTREAM 0.04 2.0E-9 (KvDMR 21) 23725790
JCEG203 * = b6GnT F30A10.4 GCNT4
STREAMRAFp-valueORBETACIStudy
DOWNSTREAM 4.0E-6 0.0888 (unit increase)] 23362303
JCEG200 * = b6GnT T28F3.9 GCNT3
JCEG189 * = b6GnT gly-1 F44F4.6 GCNT1
STREAMRAFp-valueORBETACIStudy
DOWNSTREAM 0.71 7.0E-6 1.56 [1.28-1.89] 21546767
JCEG217 * = ppGalNAcT gly-3 ZK688.8 GALNT1 602273
608369





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