JCEG ID JCEG218
Name gly-9      WormBase    NCBI Gene
Human Ortholog

GGDB:GALNT1 

OMIM:

OrthoList :   GALNT5  (Ensembl Compara)

GGDB Score E-val
GALNT1 404 e-114
GALNT13 393 e-111
GALNT12 374 e-105
GALNT4 366 e-103
GALNT11 359 e-101
GALNT3 356 e-100
GALNT5 353 6e-99
GALNT6 351 2e-98
GALNT10 341 2e-95
GALNT2 340 3e-95
GALNT14 332 1e-92
GALNT7 317 5e-88
GALNT15 297 3e-82
GALNT19 291 2e-80
GALNT9 278 1e-76
GALNT8 245 2e-66
Option tblastn : Query Worm Protein, Subject GGDB mRNA, E-val < 0.00001
Family Name ppGalNAcT
Locus Tag Y47D3A.23
RNAi phenotype
phenotype WT
Microscope observation (Image)
COPAS (Image)

Normal

hsp-4::GFP (Image)
Sequence Features
Sequence CDS
Protein
References

Hagen FK, Nehrke K J. Biol. Chem. (1998) 273 (14) :8268-77 [PMID : 9525933] cDNA cloning and expression of a family of UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase sequence homologs from Caenorhabditis elegans.

Schwientek T, Bennett EP, Flores C, Thacker J, Hollmann M, Reis CA, Behrens J, Mandel U, Keck B, Schafer MA, Haselmann K, Zubarev R, Roepstorff P, Burchell JM, Taylor-Papadimitriou J, Hollingsworth MA, Clausen H J. Biol. Chem. (2002) 277 (25) :22623-38 [PMID : 11925450] Functional conservation of subfamilies of putative UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferases in Drosophila, Caenorhabditis elegans, and mammals. One subfamily composed of l(2)35Aa is essential in Drosophila.

Wang H, Spang A, Sullivan MA, Hryhorenko J, Hagen FK Mol. Biol. Cell (2005) 16 (9) :4202-13 [PMID : 15987734] The terminal phase of cytokinesis in the Caenorhabditis elegans early embryo requires protein glycosylation.

Berninsone PM WormBook (2006) :1-22 [PMID : 18050430] Carbohydrates and glycosylation.

Berndt JD, Aoyagi A, Yang P, Anastas JN, Tang L, Moon RT J. Cell Biol. (2011) 194 (5) :737-50 [PMID : 21875946] Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling.

Shaye DD, Greenwald I PLoS ONE (2011) 6 (5) :e20085 [PMID : 21647448] OrthoList: a compendium of C. elegans genes with human orthologs.

WormBase (WS254)

Functional Descriptions gly-9
Deletion Mutants gk440
In Situ clone=163c10   
Expression Expression
db_name wbbt name def reliability expr_pattern paper WormAtlas
WB WBbt:0006876

EMS "embryonic cell" [WB:rynl] Enriched WBPaper00041506 : EMS_enriched
 WBPaper00041506

WBGene00012934
Phenotype
Homology_paralog
Observed Observed and NOT Observed
Phenotype Definition RNAi / Allele
bivulva

"Animals exhibit a secondary vulval invagination that is anterior or posterior to the primary opening depending on the the inappropriate placement of daughter cells along the anterior/posterior axis during vulval development." [WB:WBPaper00040151, WB:WBPerson712]
RNAi: WBRNAi00089664   WBPaper00040136   Observed
RNAi: WBRNAi00089665   WBPaper00040136   Observed


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