| JCEG ID |
JCEG192 |
| Name |
gly-17
WormBase
NCBI Gene
|
| Human Ortholog |
GGDB:GCNT1 G11
OMIM:
OrthoList :
GCNT7
GCNT4
GCNT2
GCNT3
GCNT1
GCNT6
(Ensembl Compara)
GWAS Catalog
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| DOWNSTREAM |
0.71 |
0.000007
|
1.56
|
|
[1.28-1.89] |
21546767
|
|
Murea M 2011-05-05 Am J Nephrol
Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes.
|
Option tblastn : Query Worm Protein, Subject GGDB mRNA, E-val < 0.00001
|
| Family Name |
b6GnT |
| Locus Tag |
T15D6.3
|
| RNAi phenotype |
|
phenotype
|
WT
|
|
Microscope observation (Image)
|
|
|
COPAS (Image)
|
Normal
|
|
hsp-4::GFP (Image)
|
|
|
| Sequence Features |
kr:Detected
tm:Detected
dxd:GVD/DEG
gg_motif:M1, M2, M3, M4, M5
|
| Sequence |
CDS
atgatccggttaaaaaacataattctaaatcttgctgtataccttacatt
tgttatattcatattattcatagctaaagcattgattccaagacttctgg
aaaatccaaatcaacgtatccacccgccgaccgatttgctagacgacttg
caaatcaattgcacgaatattctgcaaggtttcaagaatgaaaacacatt
agaattgattaatacgaaaatgattgaaaataaaatgtggaactcaacag
atagatgtcaaactctaacgtcgatgttccgattcaacaaagtaccatta
tcagaggaagaagcacgcttcccgttgtcttttgggcttcttgtgtataa
ggaactgtcacaggttctattcttgctctcatcaatatatcaacctcaaa
atgaatactgcattgcagtaggagaaaattctgccccagcattcctaatc
ttgctgaaagagctcgctaactgttttccaaatgtgtattttatgaaacg
tccaccaataaagtggggaagcttcgaaattataaattcagtgtatggtt
gtcttgaatttttgagtcacttgaaatctgattggaaatattttcaatac
ttatcaggtgttgatatcccactgaaaactaatctcgagatggttcgaat
tttgaaacgtttaaatggaactgttaacatcggaataagtacatacgagg
atcgcctcctaaatggaaaaaataaaaccgaatctccactcccgctcttc
aagtcttcactgtcctccctaataccaagaaaagctgccaattatttatc
ttcatccagcgttcctcaacaattactagaatttcttcggacaacttggg
ttgctgatgaaggattctgggggactctattcggtaacaaggacttgttc
aatgttccgggatcatttaacttcaatgatcctctcacaaatggttgggg
caattacgtatccagacaccaactttgggttgaatccgagtgtcacaact
atatgaaagatcgatcatgtgtttttggaattggagatgttccaaactta
atgaagtcaagagcattggtggctcataagctttacatagaatcagagcc
agaagcttttttctgtctattaaagagacaccgtcatcgaacgattaatc
cagatttaacatccgattctttgtaa
|
Protein
MIRLKNIILNLAVYLTFVIFILFIAKALIPRLLENPNQRIHPPTDLLDDLQINCTNILQG
FKNENTLELINTKMIENKMWNSTDRCQTLTSMFRFNKVPLSEEEARFPLSFGLLVYKELS
QVLFLLSSIYQPQNEYCIAVGENSAPAFLILLKELANCFPNVYFMKRPPIKWGSFEIINS
VYGCLEFLSHLKSDWKYFQYLSGVDIPLKTNLEMVRILKRLNGTVNIGISTYEDRLLNGK
NKTESPLPLFKSSLSSLIPRKAANYLSSSSVPQQLLEFLRTTWVADEGFWGTLFGNKDLF
NVPGSFNFNDPLTNGWGNYVSRHQLWVESECHNYMKDRSCVFGIGDVPNLMKSRALVAHK
LYIESEPEAFFCLLKRHRHRTINPDLTSDSL
|
| References |
Warren CE, Krizus A, Dennis JW
Glycobiology
(2001)
11
(11)
:979-88
[PMID : 11744632]
Complementary expression patterns of six nonessential Caenorhabditis elegans core 2/I N-acetylglucosaminyltransferase homologues.
Berninsone PM
WormBook
(2006)
:1-22
[PMID : 18050430]
Carbohydrates and glycosylation.
Shaye DD, Greenwald I
PLoS ONE
(2011)
6
(5)
:e20085
[PMID : 21647448]
OrthoList: a compendium of C. elegans genes with human orthologs.
|
| Functional Descriptions |
gly-17
gly-17 encodes a protein similar to 2/I N-acetylglucosaminyltransferase.
|
| Deletion Mutants |
|
| In Situ |
|
| Expression |
Expression
|
WBGene00001642
Phenotype
Homology_paralog
|
|
|
| Phenotype |
Definition |
RNAi / Allele |
|
embryonic lethal
|
"Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die." [WB:cab, WB:WBPaper00000179, WB:WBPaper00004403, WB:WBPaper00004540, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00024497, WB:WBPaper00024925, WB:WBPaper00025054]
|
|
|
larval arrest
|
"The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage." [WB:WBPaper00002958, WB:WBPerson2021]
|
|
|
larval lethal
|
"The animal dies at any time between hatching and onset to adulthood." [GO:0002119, WB:WBPerson712]
|
|
|
maternal sterile
|
" Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility)." [WB:cab, WB:cgc5599, WB:cgc7141, WB:WBPerson557]
|
|
|
organism morphology variant
|
"Animals exhibit variations in the form, structure or composition of any part of their anatomy compared to control animals." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00005654, WB:WBPaper00006395]
|
|
|
postembryonic development variant
|
"Any variation in the progression of an animal over time, from hatching to adulthood, compared to control." [WB:WBPerson2021]
|
|
|
slow growth
|
"Any variation that causes a reduction in growth rate compared to control." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00006395, WB:WBPaper00024497, WB:WBPerson557]
|
|
|
sterile progeny
|
"Any variation that compromises the reproductive ability of the progeny of an animal." [WB:WBPerson2021, WB:WBPerson557]
|
|
|
Variant
|
"Animals exhibit variations compared to a given control." [WB:WBPerson557]
|
|