JCEG ID JCEG189
Name gly-1      WormBase    NCBI Gene
Human Ortholog

GGDB:GCNT1 

OMIM:

OrthoList :   GCNT7   GCNT4   GCNT2   GCNT3   GCNT1   GCNT6  (Ensembl Compara)

GWAS Catalog
STREAMRAFp-valueORBETACIStudy
DOWNSTREAM 0.71 0.000007 1.56 [1.28-1.89] 21546767
GGDB Score E-val
GCNT1 130 4e-32
GCNT3 119 7e-29
GCNT2 116 7e-28
GCNT2 101 2e-23
GCNT2 88 3e-19
GCNT4 87 5e-19
Option tblastn : Query Worm Protein, Subject GGDB mRNA, E-val < 0.00001
Family Name b6GnT
Locus Tag F44F4.6
RNAi phenotype
phenotype WT
Microscope observation (Image)
COPAS (Image)

Normal

hsp-4::GFP (Image)
Sequence Features kr:Detected
tm:soluble
dxd:GTD/DES
gg_motif:M1, M2, M3, M4, M5
Sequence CDS
Protein
References

Warren CE, Krizus A, Dennis JW Glycobiology (2001) 11 (11) :979-88 [PMID : 11744632] Complementary expression patterns of six nonessential Caenorhabditis elegans core 2/I N-acetylglucosaminyltransferase homologues.

Berninsone PM WormBook (2006) :1-22 [PMID : 18050430] Carbohydrates and glycosylation.

Shaye DD, Greenwald I PLoS ONE (2011) 6 (5) :e20085 [PMID : 21647448] OrthoList: a compendium of C. elegans genes with human orthologs.

WormBase (WS254)

Functional Descriptions gly-1

gly-1 encodes a transmembrane glycosyltransferase similar to 2/I N-acetylglucosaminyltransferase; in vitro, GLY-1 demonstrates UDP-Glc:GalB1-3GalNac-R glucosyltransferase activity; gly-1 expression is detected in adult hypodermal seam cells and possibly some neurons adjacent to the anterior bulb of the pharynx; neither gly-1 loss-of-function mutations nor RNA mediated interference (RNAi) result in any obvious abnormalities, suggesting that gly-1 function is not essential for C. elegans development and/or behavior.
Deletion Mutants ev686 qa702
In Situ In Situ   
Expression Expression
db_name wbbt name def reliability expr_pattern paper WormAtlas
WB WBbt:0003679

neuron "Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses." [ISBN:0140512888] Enriched WBPaper00030839 : Larval_Pan_Neuronal
WBPaper00030839 WormAtlas
WB WBbt:0003679

neuron "Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses." [ISBN:0140512888] Enriched WBPaper00031532 : Larva_Pan_Neuronal_Enriched
WBPaper00031532 WormAtlas
WB WBbt:0005439

pharyngeal neuron "neuron of the pharyngeal nervous system." [WB:rynl] Partial WB:Expr1782 WBPaper00005030 WormAtlas
WB WBbt:0005439

pharyngeal neuron "neuron of the pharyngeal nervous system." [WB:rynl] Uncertain WB:Expr1782 WBPaper00005030 WormAtlas
WB WBbt:0005753

seam cell "a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail" [WB:rynl, WBPaper:00038216] Certain WB:Expr1782 WBPaper00005030 WormAtlas

WBGene00001626
Phenotype
Homology_paralog

Observed Observed and NOT Observed
Phenotype Definition RNAi / Allele


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