JCEG ID | JCEG154 | ||||||||
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Name | Y73B3A.3 WormBase NCBI Gene | ||||||||
Human Ortholog |
GGDB:POMGNT1 OMIM: 300492 608617 608618 608619 OrthoList : FAM3C FAM3A FAM3D FAM3B (Ensembl Compara)
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Family Name | POMGnT | ||||||||
Locus Tag | Y73B3A.3 | ||||||||
RNAi phenotype |
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Sequence Features | |||||||||
Sequence | CDS |
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Protein |
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References |
Simmer F, Moorman C, van der Linden AM, Kuijk E, van den Berghe PV, Kamath RS, Fraser AG, Ahringer J, Plasterk RH PLoS Biol. (2003) 1 (1) :E12 [PMID : 14551910] Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. Norman KR, Cordes S, Qadota H, Rahmani P, Moerman DG Dev. Biol. (2007) 309 (1) :45-55 [PMID : 17662976] UNC-97/PINCH is involved in the assembly of integrin cell adhesion complexes in Caenorhabditis elegans body wall muscle. Lockwood CA, Lynch AM, Hardin J J. Cell. Sci. (2008) 121 (Pt 9) :1477-87 [PMID : 18411252] Dynamic analysis identifies novel roles for DLG-1 subdomains in AJM-1 recruitment and LET-413-dependent apical focusing. |
Functional Descriptions |
Y73B3A.3 none available |
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Deletion Mutants | ||||||||||||||||||
In Situ | ||||||||||||||||||
Expression |
Expression
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WBGene00022205 Phenotype Homology_paralog |
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Phenotype | Definition | RNAi / Allele | ||||||||||||||||
body elongation variant
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"Any variation in the elongation of embryonic epidermal cells compared to control. In C. elegans, this elongation occurs along an anterior-posterior axis, which is required to transform the bean-shaped embryo into the elongated shape of the worm." [WB:WBPerson2021, WB:WBPerson557] |
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embryonic lethal
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"Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die." [WB:cab, WB:WBPaper00000179, WB:WBPaper00004403, WB:WBPaper00004540, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00024497, WB:WBPaper00024925, WB:WBPaper00025054] |
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multiple cytoplasmic cavities early emb
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"Multiple vesicles, vacuoles, or cavities are seen during early embryogenesis." [cgc:5599, WB:cab] |
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paralyzed arrested elongation two fold
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"Movement and elongation ceases at the two-fold stage. The myofilament lattice in body wall muscle cells is variant. However, development in embryos continues. Embryos hatch as inviable larvae." [WB:cab, WB:cgc1894] |
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protein subcellular localization variant
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"Any variation in the placement of a protein within in a cell or cellular compartment compared to control." [WB:WBPerson557] |
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slow growth
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"Any variation that causes a reduction in growth rate compared to control." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00006395, WB:WBPaper00024497, WB:WBPerson557] |
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