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JCEG ID JCEG131
Name D2045.9      WormBase    NCBI Gene
Human Ortholog

GGDB:LHL1 

OMIM:

OrthoList :   COLGALT2   COLGALT1   CERCAM  (Ensembl Compara)

Family Name Glycosyltransferase like (GTL)
Locus Tag D2045.9
RNAi phenotype
phenotype oocyte morphology variant, Dpy
Microscope observation (Image)
COPAS (Image)

Normal

hsp-4::GFP (Image)
Sequence Features tm:soluble
dxd:EDD
Sequence CDS
Protein
References

Simmer F, Moorman C, van der Linden AM, Kuijk E, van den Berghe PV, Kamath RS, Fraser AG, Ahringer J, Plasterk RH PLoS Biol. (2003) 1 (1) :E12 [PMID : 14551910] Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions.

WormBase (WS254)

Functional Descriptions D2045.9

none available
Deletion Mutants
In Situ In Situ   
Expression Expression
db_name wbbt name def reliability expr_pattern paper WormAtlas
WB WBbt:0003822

mu_int_R "right intestinal muscle cell, attach to intestine and body wall anterior to anus" [ISBN:0-87969-307-X] WB:Expr5629 WBPaper00006525
WB WBbt:0003833

mu_int_L "left intestinal muscle cell, attach to intestine and body wall anterior to anus" [ISBN:0-87969-307-X] WB:Expr5629 WBPaper00006525
WB WBbt:0004292

anal depressor muscle "a single, H-shaped cell which lies just above the anus and connects the roof of the anal canal to the dorsal bodywall; its contractions act to increase the size of the anal opening by lifting the roof of the rectum and hence facilitate expulsion of intestinal contents." [ISBN:0-87969-307-X, WBPaper:00038216] WB:Expr5629 WBPaper00006525 WormAtlas
WB WBbt:0004506

gon_herm_dtc_P "Posterior distal tip cell, inhibit meiosis in neighbouring germ cells, lead gonad during morphogenesis, herm gonad" [ISBN:0-87969-307-X] WB:Expr5629 WBPaper00006525
WB WBbt:0004520

gon_herm_dtc_A "Anterior distal tip cell, inhibit meiosis in neighbouring germ cells, lead gonad during morphogenesis, herm gonad" [ISBN:0-87969-307-X] WB:Expr5629 WBPaper00006525
WB WBbt:0005747

reproductive system WB:Expr5629 WBPaper00006525
WB WBbt:0005798

anal sphincter muscle "a saddle-shaped muscle cell that encircles the intestinal-rectal valve" [WB:rynl, WBPaper:00038216] WB:Expr5629 WBPaper00006525 WormAtlas
WB WBbt:0005813

body wall musculature "Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion." [ISBN:0-87969-433-5] WB:Expr5629 WBPaper00006525 WormAtlas
WB WBbt:0005821

vulval muscle "muscle associated with hermaphrodite vulva." [WB:rynl] WB:Expr5629 WBPaper00006525 WormAtlas
WB WBbt:0006748

vulva "female genital." [WB:rynl] WB:Expr5629 WBPaper00006525 WormAtlas
WB WBbt:0006804

body wall muscle cell "type of 95 cells that make up muscles of the body wall." [WB:rynl] Enriched WBPaper00037950 : bodywall-muscle_larva_SelectivelyEnriched, bodywall-muscle_larva_enriched
WBPaper00037950

WBGene00008426
Phenotype
Homology_paralog

Observed Observed and NOT Observed
Phenotype Definition RNAi / Allele
exploded through vulva

"The animal is ruptured at the vulva and displays an extrusion of internal organs at the site of rupture." [WB:WBPaper00027633, WB:WBPaper00031094, WB:WBPerson712]
RNAi: WBRNAi00027249   WBPaper00006395   Observed
locomotion variant

"Animals exhibit deviations in self-propelled movement on a solid medium compared to control animals." [GO:0040011, WB:cab, WB:WBPaper00024949, WB:WBPerson712]
RNAi: WBRNAi00024961   WBPaper00006395   Observed
RNAi: WBRNAi00027249   WBPaper00006395   Observed
protruding vulva

"Animals undergo incomplete vulval morphogenesis, resulting in the formation of a single protrusion at the site of the vulva." [WB:WBPaper00004408, WB:WBPerson2021]
RNAi: WBRNAi00024961   WBPaper00006395   Observed
slow growth

"Any variation that causes a reduction in growth rate compared to control." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00006395, WB:WBPaper00024497, WB:WBPerson557]
RNAi: WBRNAi00027249   WBPaper00006395   Observed
sterile progeny

"Any variation that compromises the reproductive ability of the progeny of an animal." [WB:WBPerson2021, WB:WBPerson557]
RNAi: WBRNAi00027249   WBPaper00006395   Observed


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