JCEG ID |
JCEG105 |
Name |
C31B8.7
WormBase
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Human Ortholog |
OMIM:
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Family Name |
Glyco_transf_92 |
Locus Tag |
C31B8.7
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RNAi phenotype |
phenotype
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Microscope observation (Image)
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COPAS (Image)
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hsp-4::GFP (Image)
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Sequence Features |
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Sequence |
CDS
ATGCTCAACAGAAACACGGCAATATGTTTAATAGCGCTTTGCTTCATCTCTTTTTTGTTCATGTTTTCAC GAAACACCTGTAATATACAAGAACAGTATGGAATTTCTCTCTTGCAACTTCCATTTTTCTCAAATTCCAC CGAATCATTAAAAAATATCTCTGGCTTAGTTTCACTGCAACCTGAATATGTTGAACCATTGACACCTAGA CCTACTCCATCGAAAGAAGAAGTTCCGGATTCCGGAGATGATGAGGTCGTGGGTGGAGAATCCGCCATGT CGTATTTCAAAAAGTTGTCTGGGTCTATAAAAGACTTTATAAATAGTAGATCTGGAAGCGGTGAAAAAAT AAATGTTCTGGCTGCATATTCATATAAGGATCACTTTTCTGCAACCATATCAATTCCGAAAAAGATTGGG ACAATTGCCTATTGCCGATATGTTGGAGCAGATGGAAAAGAAGTTGCGGAGCCGGTTTTATCTCAAATTT ACCCGTTTTTTGTGGTATATTGCAGTCGGAGAAACAATGTAACGACACTTGGAATTACGGGTGACAAAAA CGAATTGATTAGTACGGAGAATTCGGTTAAATTAATAAGAAGGAAATTTAAAGAATACCAACACAATGTC TCCTTCTGCCTAGCCCCAATATACGGGAAAGAGCCAAAGTGGCTTCATTTCGTGGAGCTCGTCGAGCATT ACAAATTGCAAGGCGTCAACAAATTCTTCATTTACATCCGTGAAATTAACGAGTATGATCGGAAACTAAT CGATAGCTACGTGGAAAGTGGCGAGGTGGAGATTATCGATATTCCTGGAACTGTTGCAGACGTCATTGCC CAACAGTTAATGGCTGTAGCTGATTGCCTTCTGAGAAGTCGTACCTTTTCAAAATGGTCAATTTATGCGG ATATAGACGAACGTTTGATTATGACAGATGATCGTATAACTATTGACGGATTTTTGAGAACTATAACAGA CGAGACGATCGGCTCAATAGCCTTCCCGCAACGTTGGATAATGAAGCGAGACCTACTTCCGGCAAAATTC GAAAACGACGAGCAAGTTATTGAAACGATGCCCACGCGTGCGTGGCACGAGACAACTAGCGCCGCACTGA AAGGTCATCCTGTGTGCAATGAGCAACAGAGCTGCTGGGCAAAGGATATTGTGCACAATGAAAAGGCGAT TCGAATGCTTGTTCACGAAGTGGAAACTTTTTATCCCGGATTTCGGGAATTGTTTTTAGACCCATCAATT GGTTACATAAGACACTACCGCGACGTCACAATGCAGTCTTGGGAGCACAACAACGTGGCAAATCTCAAAA AATTCGGTCCATTTTCCAACACAACGTACCCTCCAACAATAGGATCGAAATTACTGAAAAACGTGTTCAG TCGTCTTCATCGGGTTTATAATTGA
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Protein
MLNRNTAICLIALCFISFLFMFSRNTCNIQEQYGISLLQLPFFSNSTESLKNISGLVSLQPEYVEPLTPR PTPSKEEVPDSGDDEVVGGESAMSYFKKLSGSIKDFINSRSGSGEKINVLAAYSYKDHFSATISIPKKIG TIAYCRYVGADGKEVAEPVLSQIYPFFVVYCSRRNNVTTLGITGDKNELISTENSVKLIRRKFKEYQHNV SFCLAPIYGKEPKWLHFVELVEHYKLQGVNKFFIYIREINEYDRKLIDSYVESGEVEIIDIPGTVADVIA QQLMAVADCLLRSRTFSKWSIYADIDERLIMTDDRITIDGFLRTITDETIGSIAFPQRWIMKRDLLPAKF ENDEQVIETMPTRAWHETTSAALKGHPVCNEQQSCWAKDIVHNEKAIRMLVHEVETFYPGFRELFLDPSI GYIRHYRDVTMQSWEHNNVANLKKFGPFSNTTYPPTIGSKLLKNVFSRLHRVYN
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References |
Simmer F, Moorman C, van der Linden AM, Kuijk E, van den Berghe PV, Kamath RS, Fraser AG, Ahringer J, Plasterk RH
PLoS Biol.
(2003)
1
(1)
:E12
[PMID : 14551910]
Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions.
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Functional Descriptions |
C31B8.7
none available
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Deletion Mutants |
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In Situ |
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Expression |
Expression
db_name |
wbbt |
name |
def |
reliability |
expr_pattern |
paper |
WormAtlas |
WB |
WBbt:0005772
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intestine |
"A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages." [WBPaper:00038216] |
Enriched |
WBPaper00037950 : intestine_larva_SelectivelyEnriched, intestine_larva_enriched
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WBPaper00037950
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WormAtlas
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WBGene00016282
Phenotype
Homology_paralog
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Phenotype |
Definition |
RNAi / Allele |
adult lethal
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"Premature lethality during the adult stage. When applied to large-scale RNAi screens in C. elegans, this phenotype is present in at least 10% of analyzed worms, or at least 30% in the case of rrf-3 perturbed background." [WB:cab, WB:WBPaper00004402, WB:WBPaper00005654, WB:WBPaper00006395]
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embryonic lethal
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"Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die." [WB:cab, WB:WBPaper00000179, WB:WBPaper00004403, WB:WBPaper00004540, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00024497, WB:WBPaper00024925, WB:WBPaper00025054]
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larval arrest
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"The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage." [WB:WBPaper00002958, WB:WBPerson2021]
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larval lethal
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"The animal dies at any time between hatching and onset to adulthood." [GO:0002119, WB:WBPerson712]
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lethal
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"Animals die prematurely at any stage of the life cycle." [WB:WBPaper00001109, WB:WBPerson2021]
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locomotion variant
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"Animals exhibit deviations in self-propelled movement on a solid medium compared to control animals." [GO:0040011, WB:cab, WB:WBPaper00024949, WB:WBPerson712]
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maternal sterile
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" Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility)." [WB:cab, WB:cgc5599, WB:cgc7141, WB:WBPerson557]
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organism morphology variant
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"Animals exhibit variations in the form, structure or composition of any part of their anatomy compared to control animals." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00005654, WB:WBPaper00006395]
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postembryonic development variant
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"Any variation in the progression of an animal over time, from hatching to adulthood, compared to control." [WB:WBPerson2021]
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slow growth
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"Any variation that causes a reduction in growth rate compared to control." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00006395, WB:WBPaper00024497, WB:WBPerson557]
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small
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"Animals are shorter and thinner than control animals at the same developmental stage." [WB:cab, WB:cgc31]
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sterile progeny
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"Any variation that compromises the reproductive ability of the progeny of an animal." [WB:WBPerson2021, WB:WBPerson557]
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Variant
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"Animals exhibit variations compared to a given control." [WB:WBPerson557]
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