| JCEG ID |
JCEG099 |
| Name |
C14C6.8
WormBase
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| Human Ortholog |
OMIM:
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| Family Name |
Glyco_transf_92 |
| Locus Tag |
C14C6.8
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| RNAi phenotype |
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phenotype
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Microscope observation (Image)
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COPAS (Image)
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hsp-4::GFP (Image)
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| Sequence Features |
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| Sequence |
CDS
ATGAATAAAACACTACCGGCAGAATCAATTTTCAACATAACCAGCAGTGAAGTTGAGGATCCACTTTTTG
CATATAATTCGTCCGACTGTCCCTACGAGGAATGGAATCAGGTCACAACCACCATAATTCCTAACACAGA
GGTCCATGACAAATGGATGAGAACCTGGAAGCCTATAGATGAGCCTTTTCTCTATCACACAAAGCCTTCT
GCAATGTCTGCATTTGCACAAAAAGATCAGATTAGCGTGGCACTGACGTCCACTAATTTAATAAATTCAA
CAATGTATTGCCGTTACTACGATTGCCGTCGGAAAGAGATCAGTGATCCATTTCAAAGTATTATTTTTCA
CAAGTCAACGGTTTTTTGTGCTCGACGGCCCAATGCAAAGTATATTGCGGTTTCTCTGACTTTAGACGAA
ATTCCTGACTATTCAGTTCCAATCGTTCCAAGAATTGGAAATCCACCTCACTACTTCACTATTTGCATGG
CACCTCTTTATGGTGATGAGCCTAAATTTCTGCAAATCGTGGATTTTATCGAATACCATAAGCTCCAGGG
CGCCACGTTTTTCCACATTTACTTGAGAAATGTCACAGATTACGATAGAATGATGCTAGATGAATATGTT
AAAACGGGTGACATTGAGATCATAAAAATGCATGATCACTTTTGGAGAGCAGATTATATGTGGCATGAAG
TTCAAATTAATGACTGCCACCATCGCAGCAAGTATTTCTCAAAATGGACAGCTCTGATAGATATTGACGA
GAGGTTGGAGATTAGAAATGAGCAATTTAAGACAGTGGTGGACTATTTAGACTCAATCCACAATGCGTCA
GTTGCGAACCTACATTTTCGAGTAAAATGGGTTATGAAGCATAACAATACACCTGCGAGATATGAGAATG
ATGCACAGCTGACGGATGAAATGCTCTTCTGCAAATTCCGAAACACTTCCCGGCTCGGAGAGCTTTGGGA
TCAACCCAAGTGTATTATTCGTCCGGAAAATGTTGCAATTATGACTATTCATGGGCCATTGGCAATGTAC
AAAGGGGAGACAATCACGCTTGTTAATATAAATATTGGCTTTATAAGACATTATCGAAGCGTGGAGCAAA
GAGTTTTCCCGGGAGCTCTTGATAGAATGATGTCACATGCTCCATTTAACATTCTACCAATAGAGCAGTG
GGTTGAGCAAAACCTGACAAAAAATATATTGAGCCGAGTAAAATTGGTCTACGATATTGTTGATGTGTCG
TGTGAAGAGAAGATAAAGATGTATAGCATTGAAAATGTTACGGCGCCTTGCTCAATTGGGAAACAAGACC
TGTTCACTAAACTATAA
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Protein
MNKTLPAESIFNITSSEVEDPLFAYNSSDCPYEEWNQVTTTIIPNTEVHDKWMRTWKPIDEPFLYHTKPS
AMSAFAQKDQISVALTSTNLINSTMYCRYYDCRRKEISDPFQSIIFHKSTVFCARRPNAKYIAVSLTLDE
IPDYSVPIVPRIGNPPHYFTICMAPLYGDEPKFLQIVDFIEYHKLQGATFFHIYLRNVTDYDRMMLDEYV
KTGDIEIIKMHDHFWRADYMWHEVQINDCHHRSKYFSKWTALIDIDERLEIRNEQFKTVVDYLDSIHNAS
VANLHFRVKWVMKHNNTPARYENDAQLTDEMLFCKFRNTSRLGELWDQPKCIIRPENVAIMTIHGPLAMY
KGETITLVNINIGFIRHYRSVEQRVFPGALDRMMSHAPFNILPIEQWVEQNLTKNILSRVKLVYDIVDVS
CEEKIKMYSIENVTAPCSIGKQDLFTKL
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| References |
Ashrafi K, Chang FY, Watts JL, Fraser AG, Kamath RS, Ahringer J, Ruvkun G
Nature
(2003)
421
(6920)
:268-72
[PMID : 12529643]
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes.
|
| Functional Descriptions |
C14C6.8
none available
|
| Deletion Mutants |
|
| In Situ |
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| Expression |
Expression
| db_name |
wbbt |
name |
def |
reliability |
expr_pattern |
paper |
WormAtlas |
| WB |
WBbt:0005772
|
intestine |
"A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages." [WBPaper:00038216] |
Enriched |
WBPaper00026980 : intestine_enriched
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WBPaper00026980
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WormAtlas
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Phenotype
WBGene00015762
Homology_paralog
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| Phenotype |
Definition |
RNAi / Allele |
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embryonic lethal
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"Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die." [WB:cab, WB:WBPaper00000179, WB:WBPaper00004403, WB:WBPaper00004540, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00024497, WB:WBPaper00024925, WB:WBPaper00025054]
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fat content reduced
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"Animals exhibit less fat or lipid than observed in control animals." [GO:0019915, WB:WBPaper00032082, WB:WBPerson712]
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fat content variant
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"Animals exhibit variations in the amount of fat or lipids present in the organism compared to control animals." [GO:0019915, WB:WBPaper00032082, WB:WBPerson712]
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larval arrest
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"The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage." [WB:WBPaper00002958, WB:WBPerson2021]
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larval lethal
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"The animal dies at any time between hatching and onset to adulthood." [GO:0002119, WB:WBPerson712]
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lethal
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"Animals die prematurely at any stage of the life cycle." [WB:WBPaper00001109, WB:WBPerson2021]
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maternal sterile
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" Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility)." [WB:cab, WB:cgc5599, WB:cgc7141, WB:WBPerson557]
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organism morphology variant
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"Animals exhibit variations in the form, structure or composition of any part of their anatomy compared to control animals." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00005654, WB:WBPaper00006395]
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postembryonic development variant
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"Any variation in the progression of an animal over time, from hatching to adulthood, compared to control." [WB:WBPerson2021]
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slow growth
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"Any variation that causes a reduction in growth rate compared to control." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00006395, WB:WBPaper00024497, WB:WBPerson557]
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sterile progeny
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"Any variation that compromises the reproductive ability of the progeny of an animal." [WB:WBPerson2021, WB:WBPerson557]
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Variant
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"Animals exhibit variations compared to a given control." [WB:WBPerson557]
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