JCEG ID JCEG096
Name glct-6      WormBase    NCBI Gene
Human Ortholog

GGDB:B3GAT1 

OMIM: 151290 245600 606374 607497

OrthoList :   B3GAT3   B3GAT2   B3GAT1  (Ensembl Compara)

GWAS Catalog
STREAMRAFp-valueORBETACIStudy
UPSTREAM 0.000008 4.35 [2.28-8.30] 24172245
MAPPED 0.000003 0.701 (unit decrease)] 24277619
UPSTREAM 0.000002 0.64 (unit increase) [0.39-0.89] 25562672
UPSTREAM 0.889723713 0.000009 (IGP36) 0.227 (unit decrease) [0.13-0.33] 23382691
UPSTREAM 0.871 0.000002 [NR] 23049088
DOWNSTREAM 0.53 0.000005 (CERAD-dr) 0.2826 (unit decrease) [0.16-0.4] 25648963
UPSTREAM 0.143 0.0000007 [NR] 23049088
GGDB Score E-val
B3GAT1 164 2e-42
B3GAT3 152 7e-39
B3GAT2 145 1e-36
Option tblastn : Query Worm Protein, Subject GGDB mRNA, E-val < 0.00001
Family Name Glucuronyltransferase(GlcAT)
Locus Tag W07G9.2
RNAi phenotype
phenotype
Microscope observation (Image)
COPAS (Image)
hsp-4::GFP (Image)
Sequence Features tm:soluble
dxd:DDD
gg_motif:M4
Sequence CDS
Protein
References

Shaye DD, Greenwald I PLoS ONE (2011) 6 (5) :e20085 [PMID : 21647448] OrthoList: a compendium of C. elegans genes with human orthologs.

WormBase (WS254)

Functional Descriptions glct-6

Deletion Mutants
In Situ
Expression Expression
db_name wbbt name def reliability expr_pattern paper WormAtlas
WB WBbt:0003679

neuron "Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses." [ISBN:0140512888] Enriched WBPaper00030839 : Larval_Pan_Neuronal
WBPaper00030839 WormAtlas
WB WBbt:0005751

coelomocyte "A free-floating spherical cell lying in the pseudocoelomic cavity of larvae and adult C. elegans which can endocytose many compounds, possibly for immune surveillance. There are six coelomocytes in adult hermaphrodites, and they display prominent cytoplasmic inclusions and vacuoles." [WBPaper:00038216] Enriched WBPaper00037950 : coelomocytes_embryo_enriched
WBPaper00037950 WormAtlas
WB WBbt:0005772

intestine "A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages." [WBPaper:00038216] Enriched WBPaper00026980 : intestine_enriched
WBPaper00026980 WormAtlas
WB WBbt:0005812

excretory cell "H-shaped cell associated with the excretory system, largest cell in C. elegans." [WB:rynl] Enriched WBPaper00037950 : excretory-cell_larva_enriched
WBPaper00037950 WormAtlas

WBGene00019546
Phenotype
Homology_paralog

Observed Observed and NOT Observed
Phenotype Definition RNAi / Allele
dauer lifespan extended

"The life span of dauer-staged animals is longer than that observed in control dauer animals." [WB:WBPaper00032396, WB:WBPerson2987]
RNAi: WBRNAi00103571   WBPaper00041478   Observed
extended life span

"The duration of viability in the adult phase of the life-cycle surpasses that of control animals." [GO:0008340, WB:WBPerson712]
RNAi: WBRNAi00078601   WBPaper00030830   Observed
paraquat resistant

"Animals fail to respond to the concentration of paraquat that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." [WB:WBPerson557]
RNAi: WBRNAi00078668   WBPaper00030830   Observed


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