JCEG ID JCEG084
Name gly-20      WormBase    NCBI Gene
Human Ortholog

GGDB:MGAT2 

OMIM: 212066 602616

OrthoList :   MGAT2  (Ensembl Compara)

GGDB Score E-val
MGAT2 304 2e-84
Option tblastn : Query Worm Protein, Subject GGDB mRNA, E-val < 0.00001
Family Name GlcNAcT(GnT)
Locus Tag C03E10.4
RNAi phenotype
phenotype WT
Microscope observation (Image)
COPAS (Image)

Normal

hsp-4::GFP (Image)
Sequence Features kr:Detected
tm:Detected
dxd:EDD
gg_motif:M1, M2, M3, M4, M5
Sequence CDS
Protein
References

Chen S, Tan J, Reinhold VN, Spence AM, Schachter H Biochim. Biophys. Acta (2002) 1573 (3) :271-9 [PMID : 12417409] UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I and UDP-N-acetylglucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II in Caenorhabditis elegans.

Kayser EB, Morgan PG, Sedensky MM Anesthesiology (2004) 101 (2) :365-72 [PMID : 15277919] Mitochondrial complex I function affects halothane sensitivity in Caenorhabditis elegans.

Zhu S, Hanneman A, Reinhold VN, Spence AM, Schachter H Biochem. J. (2004) 382 (Pt 3) :995-1001 [PMID : 15228383] Caenorhabditis elegans triple null mutant lacking UDP-N-acetyl-D-glucosamine:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I.

Kayser EB, Sedensky MM, Morgan PG, Hoppel CL J. Biol. Chem. (2004) 279 (52) :54479-86 [PMID : 15269213] Mitochondrial oxidative phosphorylation is defective in the long-lived mutant clk-1.

Gunther CV, Riddle DL J. Biol. Chem. (2004) 279 (38) :39555-64 [PMID : 15254038] Alternative polyadenylation results in a truncated daf-4 BMP receptor that antagonizes DAF-7-mediated development in Caenorhabditis elegans.

Liu J, Vasudevan S, Kipreos ET Development (2004) 131 (15) :3513-25 [PMID : 15215209] CUL-2 and ZYG-11 promote meiotic anaphase II and the proper placement of the anterior-posterior axis in C. elegans.

Sonneville R, Gonczy P Development (2004) 131 (15) :3527-43 [PMID : 15215208] Zyg-11 and cul-2 regulate progression through meiosis II and polarity establishment in C. elegans.

Berninsone PM WormBook (2006) :1-22 [PMID : 18050430] Carbohydrates and glycosylation.

Shaye DD, Greenwald I PLoS ONE (2011) 6 (5) :e20085 [PMID : 21647448] OrthoList: a compendium of C. elegans genes with human orthologs.

Palmberger D, Wilson IB, Berger I, Grabherr R, Rendic D PLoS ONE (2012) 7 (4) :e34226 [PMID : 22485160] SweetBac: a new approach for the production of mammalianised glycoproteins in insect cells.

LeGendre JB, Campbell ZT, Kroll-Conner P, Anderson P, Kimble J, Wickens M J. Biol. Chem. (2012) 288 (4) :2532-45 [PMID : 23195953] RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans.

WormBase (WS254)

Functional Descriptions gly-20

gly-20 encodes an N-acetylglucosaminyltransferase II (GnTII); by homology, GLY-20 is predicted to function in the Golgi to effect protein N-glycosylation; expression of C. elegans GLY-20 and bovine beta1,4-galactosyltransferase I in a baculoviral insect cell system results in efficient glycosylation of mammalian proteins.
Deletion Mutants ok826
In Situ clone=579d10   
Expression Expression
db_name wbbt name def reliability expr_pattern paper WormAtlas
WB WBbt:0005751

coelomocyte "A free-floating spherical cell lying in the pseudocoelomic cavity of larvae and adult C. elegans which can endocytose many compounds, possibly for immune surveillance. There are six coelomocytes in adult hermaphrodites, and they display prominent cytoplasmic inclusions and vacuoles." [WBPaper:00038216] Enriched WBPaper00037950 : coelomocytes_embryo_enriched
 WBPaper00037950 WormAtlas
WB WBbt:0005813

body wall musculature "Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion." [ISBN:0-87969-433-5] Enriched WBPaper00040985 : AIN-2_asynchronous_muscle
 WBPaper00040985 WormAtlas

WBGene00001645
Phenotype
Homology_paralog
Observed Observed and NOT Observed
Phenotype Definition RNAi / Allele


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