JCEG ID | JCEG084 | ||||||||
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Name | gly-20 WormBase NCBI Gene | ||||||||
Human Ortholog |
GGDB:MGAT2 OrthoList : MGAT2 (Ensembl Compara)
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Family Name | GlcNAcT(GnT) | ||||||||
Locus Tag | C03E10.4 | ||||||||
RNAi phenotype |
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Sequence Features |
kr:Detected tm:Detected dxd:EDD gg_motif:M1, M2, M3, M4, M5 |
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Sequence | CDS |
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Protein |
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References |
Chen S, Tan J, Reinhold VN, Spence AM, Schachter H Biochim. Biophys. Acta (2002) 1573 (3) :271-9 [PMID : 12417409] UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I and UDP-N-acetylglucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II in Caenorhabditis elegans. Kayser EB, Morgan PG, Sedensky MM Anesthesiology (2004) 101 (2) :365-72 [PMID : 15277919] Mitochondrial complex I function affects halothane sensitivity in Caenorhabditis elegans. Zhu S, Hanneman A, Reinhold VN, Spence AM, Schachter H Biochem. J. (2004) 382 (Pt 3) :995-1001 [PMID : 15228383] Caenorhabditis elegans triple null mutant lacking UDP-N-acetyl-D-glucosamine:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I. Kayser EB, Sedensky MM, Morgan PG, Hoppel CL J. Biol. Chem. (2004) 279 (52) :54479-86 [PMID : 15269213] Mitochondrial oxidative phosphorylation is defective in the long-lived mutant clk-1. Gunther CV, Riddle DL J. Biol. Chem. (2004) 279 (38) :39555-64 [PMID : 15254038] Alternative polyadenylation results in a truncated daf-4 BMP receptor that antagonizes DAF-7-mediated development in Caenorhabditis elegans. Liu J, Vasudevan S, Kipreos ET Development (2004) 131 (15) :3513-25 [PMID : 15215209] CUL-2 and ZYG-11 promote meiotic anaphase II and the proper placement of the anterior-posterior axis in C. elegans. Sonneville R, Gonczy P Development (2004) 131 (15) :3527-43 [PMID : 15215208] Zyg-11 and cul-2 regulate progression through meiosis II and polarity establishment in C. elegans. Berninsone PM WormBook (2006) :1-22 [PMID : 18050430] Carbohydrates and glycosylation. Shaye DD, Greenwald I PLoS ONE (2011) 6 (5) :e20085 [PMID : 21647448] OrthoList: a compendium of C. elegans genes with human orthologs. Palmberger D, Wilson IB, Berger I, Grabherr R, Rendic D PLoS ONE (2012) 7 (4) :e34226 [PMID : 22485160] SweetBac: a new approach for the production of mammalianised glycoproteins in insect cells. LeGendre JB, Campbell ZT, Kroll-Conner P, Anderson P, Kimble J, Wickens M J. Biol. Chem. (2012) 288 (4) :2532-45 [PMID : 23195953] RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. |
Functional Descriptions |
gly-20 gly-20 encodes an N-acetylglucosaminyltransferase II (GnTII); by homology, GLY-20 is predicted to function in the Golgi to effect protein N-glycosylation; expression of C. elegans GLY-20 and bovine beta1,4-galactosyltransferase I in a baculoviral insect cell system results in efficient glycosylation of mammalian proteins. |
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Deletion Mutants | ok826 | |||||||||||||||||||||||||
In Situ | clone=579d10 | |||||||||||||||||||||||||
Expression |
Expression
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WBGene00001645 Phenotype Homology_paralog |
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Phenotype | Definition | RNAi / Allele |