| JCEG ID |
JCEG030 |
| Name |
EGAP9.3
WormBase
NCBI Gene
|
| Human Ortholog |
GGDB:FUT1
OMIM:
GWAS Catalog
| STREAM | RAF | p-value | OR | BETA | CI | Study |
| MAPPED |
|
0.0000000003
|
|
|
|
24941225
|
|
Liang Y 2014-06-18 PLoS One
Genetic variations affecting serum carcinoembryonic antigen levels and status of regional lymph nodes in patients with sporadic colorectal cancer from Southern China.
|
|
| Family Name |
Fucosyltransferases |
| Locus Tag |
EGAP9.3
|
| RNAi phenotype |
|
phenotype
|
WT
|
|
Microscope observation (Image)
|
|
|
COPAS (Image)
|
Normal
|
|
hsp-4::GFP (Image)
|
|
|
| Sequence Features |
kr:Detected
tm:Detected
gg_motif:M1,M3
|
| Sequence |
CDS
atgcgatatgtcagaggagtttttaactacagaaaaaatcataaaatttt
gtttatagtaatacttgtgatcttgctgatttcaattgtcaattggatgg
ttccccgctactatgactacagacagattcccacgaaagtttattgtgat
aagaatgaaattgataaacagaaatatttattatttcctatgaccgcaat
tgtttttgatggaggtttgggaaaccaactttttgaagtattttcacttc
ttggacttgctatgaaactcaaccgaactgcaattttcaatagcgatgac
tggattcttcactcaaagttagatttacttcaagagcaagtaccccaggt
tgctgcaagaattatttccatcccaattgagattgctgaatccactcgat
ttttatactctccagcatgttgtcattatcaatttgcatctctcctttcc
tgcgaacaaaacaggtttcttatcattgatggacaatattttcagagttt
taaatacttctcaacgatagagtcttcaataagaaaatggttgaagcctc
cacaggacgaagagatgtttttgaaaaaaatgatcagaagaaaggatgaa
ttacgatacaaacactgtgttcacattcgtcgtggtgattttacgacaga
ctcccaacacgctggaactgatgcggtctttacaattcgagcaattgatt
atttgtattccctgcatcctggtctcatatatctcttcagtaatgatcca
gaatgggttaggaagagaatagctgaacaacttgactatcatggtgatgt
taaaattatggaaacaccaaaagacgcagccatcaaggacttatatttct
cccaggttcattgtgattctgtgttgattactgctccatcgtcaacattc
ggttggtggattggatatatgtcaaagaatcaatcaaatgtatattatcg
agatattcaagaaactgaggatatggtcaaatatcaaatgttggaagaag
atttcttcccgcgcacgtggaaaaagttgggaatgtcacgaaacgggtta
atcatcacaaagtaa
|
Protein
MRYVRGVFNYRKNHKILFIVILVILLISIVNWMVPRYYDYRQIPTKVYCDKNEIDKQKYL
LFPMTAIVFDGGLGNQLFEVFSLLGLAMKLNRTAIFNSDDWILHSKLDLLQEQVPQVAAR
IISIPIEIAESTRFLYSPACCHYQFASLLSCEQNRFLIIDGQYFQSFKYFSTIESSIRKW
LKPPQDEEMFLKKMIRRKDELRYKHCVHIRRGDFTTDSQHAGTDAVFTIRAIDYLYSLHP
GLIYLFSNDPEWVRKRIAEQLDYHGDVKIMETPKDAAIKDLYFSQVHCDSVLITAPSSTF
GWWIGYMSKNQSNVYYRDIQETEDMVKYQMLEEDFFPRTWKKLGMSRNGLIITK
|
| References |
|
| Functional Descriptions |
EGAP9.3
none available
|
| Deletion Mutants |
|
| In Situ |
In Situ
|
| Expression |
Expression
| db_name |
wbbt |
name |
def |
reliability |
expr_pattern |
paper |
WormAtlas |
| WB |
WBbt:0005772
|
intestine |
"A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages." [WBPaper:00038216] |
Enriched |
WBPaper00040985 : AIN-2_asynchronous_intestine
|
WBPaper00040985
|
WormAtlas
|
|
WBGene00017151
Phenotype
Homology_paralog
|
|
|
| Phenotype |
Definition |
RNAi / Allele |
|
embryonic lethal
|
"Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die." [WB:cab, WB:WBPaper00000179, WB:WBPaper00004403, WB:WBPaper00004540, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00024497, WB:WBPaper00024925, WB:WBPaper00025054]
|
|
|
larval arrest
|
"The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage." [WB:WBPaper00002958, WB:WBPerson2021]
|
|
|
larval lethal
|
"The animal dies at any time between hatching and onset to adulthood." [GO:0002119, WB:WBPerson712]
|
|
|
maternal sterile
|
" Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility)." [WB:cab, WB:cgc5599, WB:cgc7141, WB:WBPerson557]
|
|
|
organism morphology variant
|
"Animals exhibit variations in the form, structure or composition of any part of their anatomy compared to control animals." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00005654, WB:WBPaper00006395]
|
|
|
postembryonic development variant
|
"Any variation in the progression of an animal over time, from hatching to adulthood, compared to control." [WB:WBPerson2021]
|
|
|
slow growth
|
"Any variation that causes a reduction in growth rate compared to control." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00006395, WB:WBPaper00024497, WB:WBPerson557]
|
|
|
sterile progeny
|
"Any variation that compromises the reproductive ability of the progeny of an animal." [WB:WBPerson2021, WB:WBPerson557]
|
|
|
Variant
|
"Animals exhibit variations compared to a given control." [WB:WBPerson557]
|
|
