Functional Descriptions |
C08B11.8
none available
|
Deletion Mutants |
tm1822
tm1806
tm1607
tm1148
tm1744
tm1540
|
In Situ |
|
Expression |
Expression
db_name |
wbbt |
name |
def |
reliability |
expr_pattern |
paper |
WormAtlas |
WB |
WBbt:0005063
|
gon_male_dtc posterior |
"Distal tip cell, inhibits meiosis in nearby germ cells, posterior." [ISBN:0-87969-307-X] |
Enriched |
WBPaper00048690 : hermaphrodite-Z1-Z4-daughter_enriched
|
WBPaper00048690
|
|
WB |
WBbt:0005064
|
gon_male_dtc anterior |
"Distal tip cell, inhibits meiosis in nearby germ cells, anterior" [ISBN:0-87969-307-X] |
Enriched |
WBPaper00048690 : hermaphrodite-Z1-Z4-daughter_enriched
|
WBPaper00048690
|
|
WB |
WBbt:0005751
|
coelomocyte |
"A free-floating spherical cell lying in the pseudocoelomic cavity of larvae and adult C. elegans which can endocytose many compounds, possibly for immune surveillance. There are six coelomocytes in adult hermaphrodites, and they display prominent cytoplasmic inclusions and vacuoles." [WBPaper:00038216] |
Enriched |
WBPaper00037950 : coelomocytes_embryo_enriched
|
WBPaper00037950
|
WormAtlas
|
WB |
WBbt:0005784
|
germ line |
"cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes." [ISBN:0140512888] |
Enriched |
WBPaper00044760 : germline_specific
|
WBPaper00044760
|
|
WB |
WBbt:0007023
|
Z1.p |
"cell, posterior descendent of Z1." [WB:rynl] |
Enriched |
WBPaper00048690 : hermaphrodite-Z1-Z4-daughter_enriched
|
WBPaper00048690
|
|
WB |
WBbt:0007025
|
Z4.a |
"cell, anterior descendent of Z4." [WB:rynl] |
Enriched |
WBPaper00048690 : hermaphrodite-Z1-Z4-daughter_enriched
|
WBPaper00048690
|
|
|
WBGene00007435
Phenotype
Homology_paralog
|
|
Phenotype |
Definition |
RNAi / Allele |
dauer arrest variant
|
"Animals exhibit variations in the entry/exit into a state of arrested tissue development during the dauer larval stage in response to harsh environmental conditions, compared to control. In C. elegans, the dauer larva enters a state of arrest in which no developmental changes occur, until the animal finds more suitable growing conditions, or until it spontaneously shifts back into a normal developmental schedule. (WormAtlas)." [WB:WBPerson2021, WB:WBPerson557]
|
|
embryonic lethal
|
"Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die." [WB:cab, WB:WBPaper00000179, WB:WBPaper00004403, WB:WBPaper00004540, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00024497, WB:WBPaper00024925, WB:WBPaper00025054]
|
|
extended life span
|
"The duration of viability in the adult phase of the life-cycle surpasses that of control animals." [GO:0008340, WB:WBPerson712]
|
|
fat content increased
|
"Animals exhibit a greater amount of fat or lipids than observed in control animals." [GO:0019915, WB:WBPaper00032082, WB:WBPerson712]
|
|
fat content reduced
|
"Animals exhibit less fat or lipid than observed in control animals." [GO:0019915, WB:WBPaper00032082, WB:WBPerson712]
|
|
larval arrest
|
"The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage." [WB:WBPaper00002958, WB:WBPerson2021]
|
|
larval lethal
|
"The animal dies at any time between hatching and onset to adulthood." [GO:0002119, WB:WBPerson712]
|
|
lethal
|
"Animals die prematurely at any stage of the life cycle." [WB:WBPaper00001109, WB:WBPerson2021]
|
|
maternal sterile
|
" Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility)." [WB:cab, WB:cgc5599, WB:cgc7141, WB:WBPerson557]
|
|
organism morphology variant
|
"Animals exhibit variations in the form, structure or composition of any part of their anatomy compared to control animals." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00005654, WB:WBPaper00006395]
|
|
postembryonic development variant
|
"Any variation in the progression of an animal over time, from hatching to adulthood, compared to control." [WB:WBPerson2021]
|
|
protein aggregation variant
|
"Variations that result in the accumulation of soluble/insoluble protein aggregates in a particular cell or tissue, compared to control. Protein aggregates are often formed by interactions between misfolded protein molecules and/or deficiencies in proper protein folding." [WB:WBPaper00034765, WB:WBPerson2021]
|
|
shortened life span
|
"The duration of viability in the adult phase of the life-cycle is less than that of control animals." [GO:0008340, WB:WBPerson712]
|
|
slow growth
|
"Any variation that causes a reduction in growth rate compared to control." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00006395, WB:WBPaper00024497, WB:WBPerson557]
|
|
sterile progeny
|
"Any variation that compromises the reproductive ability of the progeny of an animal." [WB:WBPerson2021, WB:WBPerson557]
|
|
transgene subcellular localization variant
|
"Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals." [WB:WBPerson557]
|
|
Variant
|
"Animals exhibit variations compared to a given control." [WB:WBPerson557]
|
|