| JCEG ID |
JCEG004 |
| Name |
K09E4.2
WormBase
NCBI Gene
|
| Human Ortholog |
GGDB:ALG3
OMIM:
601110
608750
OrthoList :
ALG3
(Ensembl Compara)
| GGDB |
Score |
E-val |
|
ALG3
|
296 |
1e-81 |
Option tblastn : Query Worm Protein, Subject GGDB mRNA, E-val < 0.00001
|
| Family Name |
Asparagine-linked glycosylation (ALG) genes |
| Locus Tag |
K09E4.2
|
| RNAi phenotype |
|
phenotype
|
WT
|
|
Microscope observation (Image)
|
|
|
COPAS (Image)
|
|
|
hsp-4::GFP (Image)
|
Normal
|
|
| Sequence Features |
kr:Detected
tm:Detected
|
| Sequence |
CDS
atgcgagagttaatctctcggctagtggttggcctattttcggtcaatga
tacgggatttagagcagttgcggcgctgctgatgattgccgaagccgttt
tatcacatttagtcattttaaaagttaattacaccgaaatcgactggagc
acgtatatgcaacaagtcgagtgctacgtgaacaaggggatcctcaacta
cacgcaaatcggcggtgacacgggtccctgcgtctacccggccggccatc
tcttcgtcttccgcttgctccactttttcacgagctccggccgcaatatc
cgcgcggctcagcacattttccaaggattctacatgtttaatctatttat
ggtctttcgaatccttcacaagactatgcggatcccgccgatcgtgctgc
ttctcgtgtcgatcaccggctatcggatacactcgattttcgtgttgcgg
ctcttcaacgatcctctagctatgatgctcttctacgtggcaatggatcg
gtttttggagcaaaaatggcttgtcggatgtgttttttatagcctggcag
tatcgattaaaatgaacgtgttgcttttcgcgccggcgctgttcttcaca
cttttgctcaacaatagttatatggcgacgttgggatatttgacagtttg
cgggctaatccaactgtacgtcggtggcccattcctcctctacgactgga
aatcgtatctgcaacaatccttcgatttgggccgagttttcatgttcaaa
tggactgtcaactggcgattcttgcccgaagagtttttcctcgacaagcg
attccacgcggcacttttggttgggcatttgacgtttttggcggttttcg
cgtcgtacatgtggtttagacgcctaaacggtctccgcacctcggtctac
ctacgtcttttcgaaggcatcaccaccaccacaggcgccgtcgagaccta
ctacgccttctgtacctcaaatctgatcggaatcgccttctcccgatccc
ttcactaccagttctacagttggtacttccatcagataccgttccttctc
ttctgcgactatccccacgtggcaagtgtctccacgattccgtggcgtca
atttctgtggaaagtaccgttgctcgccgccgtcgagctcagctggaacg
tctatccatcgacgtggtggagttctgcgttgctccacgtttgccacgtc
atcattttctggcatctaatcgtgacgagacccgcgcgacctggcgattc
agtgtccagggagacgctccgaaggcttgagcagcggcagaaaatgcttg
agcaagagctccgagagcatggacaagttgtgccgaaattcaaatttcca
gcgtttttggaagagcagcaggaagagcaagtggatgttcggaagaggat
gaagcagccgattggggagaagaggacgaaaaagcagttggatgcggaat
ttgagacgtatttcgaggagcagatggacggatttcgggaggagcacacg
atttattacacccacgatggaaaaccgcaagtttctgggcttgcaccact
ggataagccggaaaaaatgaagatgcacgagaaagttgcagcattatata
cgcaggcgctgaagctacaagctcaattaaatcccaatgaaactccaaca
acatggaaatcattcaaatttcccaaaaatgccgacaaaaacctgctgga
aagctatctgaagcttcacggagcaggagcacaacaagactctgaagaat
ctgaaatttcctcagccgaagaagaagcttcagacgacgagaatagcggt
gaggaagagcccaatacggagaaaattgagcaaaattcgtgtaaagctga
agcctcggagcaagagagcaatggaggtgtgaggcggcgaattttggtcg
attaa
atgcaacaagtcgagtgctacgtgaacaaggggatcctcaactacacgca
aatcggcggtgacacgggtccctgcgtctacccggccggccatctcttcg
tcttccgcttgctccactttttcacgagctccggccgcaatatccgcgcg
gctcagcacattttccaaggattctacatgtttaatctatttatggtctt
tcgaatccttcacaagactatgcggatcccgccgatcgtgctgcttctcg
tgtcgatcaccggctatcggatacactcgattttcgtgttgcggctcttc
aacgatcctctagctatgatgctcttctacgtggcaatggatcggttttt
ggagcaaaaatggcttgtcggatgtgttttttatagcctggcagtatcga
ttaaaatgaacgtgttgcttttcgcgccggcgctgttcttcacacttttg
ctcaacaatagttatatggcgacgttgggatatttgacagtttgcgggct
aatccaactgtacgtcggtggcccattcctcctctacgactggaaatcgt
atctgcaacaatccttcgatttgggccgagttttcatgttcaaatggact
gtcaactggcgattcttgcccgaagagtttttcctcgacaagcgattcca
cgcggcacttttggttgggcatttgacgtttttggcggttttcgcgtcgt
acatgtggtttagacgcctaaacggtctccgcacctcggtctacctacgt
cttttcgaaggcatcaccaccaccacaggcgccgtcgagacctactacgc
cttctgtacctcaaatctgatcggaatcgccttctcccgatcccttcact
accagttctacagttggtacttccatcagataccgttccttctcttctgc
gactatccccacgtggcaagtgtctccacgattccgtggcgtcaatttct
gtggaaagtaccgttgctcgccgccgtcgagctcagctggaacgtctatc
catcgacgtggtggagttctgcgttgctccacgtttgccacgtcatcatt
ttctggcatctaatcgtgacgagacccgcgcgacctggcgattcagtgtc
cagggagacgctccgaaggcttgagcagcggcagaaaatgcttgagcaag
agctccgagagcatggacaagttgtgccgaaattcaaatttccagcgttt
ttggaagagcagcaggaagagcaagtggatgttcggaagaggatgaagca
gccgattggggagaagaggacgaaaaagcagttggatgcggaatttgaga
cgtatttcgaggagcagatggacggatttcgggaggagcacacgatttat
tacacccacgatggaaaaccgcaagtttctgggcttgcaccactggataa
gccggaaaaaatgaagatgcacgagaaagttgcagcattatatacgcagg
cgctgaagctacaagctcaattaaatcccaatgaaactccaacaacatgg
aaatcattcaaatttcccaaaaatgccgacaaaaacctgctggaaagcta
tctgaagcttcacggagcaggagcacaacaagactctgaagaatctgaaa
tttcctcagccgaagaagaagcttcagacgacgagaatagcggtgaggaa
gagcccaatacggagaaaattgagcaaaattcgtgtaaagctgaagcctc
ggagcaagagagcaatggaggtgtgaggcggcgaattttggtcgattaa
|
Protein
MRELISRLVVGLFSVNDTGFRAVAALLMIAEAVLSHLVILKVNYTEIDWSTYMQQVECYV
NKGILNYTQIGGDTGPCVYPAGHLFVFRLLHFFTSSGRNIRAAQHIFQGFYMFNLFMVFR
ILHKTMRIPPIVLLLVSITGYRIHSIFVLRLFNDPLAMMLFYVAMDRFLEQKWLVGCVFY
SLAVSIKMNVLLFAPALFFTLLLNNSYMATLGYLTVCGLIQLYVGGPFLLYDWKSYLQQS
FDLGRVFMFKWTVNWRFLPEEFFLDKRFHAALLVGHLTFLAVFASYMWFRRLNGLRTSVY
LRLFEGITTTTGAVETYYAFCTSNLIGIAFSRSLHYQFYSWYFHQIPFLLFCDYPHVASV
STIPWRQFLWKVPLLAAVELSWNVYPSTWWSSALLHVCHVIIFWHLIVTRPARPGDSVSR
ETLRRLEQRQKMLEQELREHGQVVPKFKFPAFLEEQQEEQVDVRKRMKQPIGEKRTKKQL
DAEFETYFEEQMDGFREEHTIYYTHDGKPQVSGLAPLDKPEKMKMHEKVAALYTQALKLQ
AQLNPNETPTTWKSFKFPKNADKNLLESYLKLHGAGAQQDSEESEISSAEEEASDDENSG
EEEPNTEKIEQNSCKAEASEQESNGGVRRRILVD
MQQVECYVNKGILNYTQIGGDTGPCVYPAGHLFVFRLLHFFTSSGRNIRAAQHIFQGFYM
FNLFMVFRILHKTMRIPPIVLLLVSITGYRIHSIFVLRLFNDPLAMMLFYVAMDRFLEQK
WLVGCVFYSLAVSIKMNVLLFAPALFFTLLLNNSYMATLGYLTVCGLIQLYVGGPFLLYD
WKSYLQQSFDLGRVFMFKWTVNWRFLPEEFFLDKRFHAALLVGHLTFLAVFASYMWFRRL
NGLRTSVYLRLFEGITTTTGAVETYYAFCTSNLIGIAFSRSLHYQFYSWYFHQIPFLLFC
DYPHVASVSTIPWRQFLWKVPLLAAVELSWNVYPSTWWSSALLHVCHVIIFWHLIVTRPA
RPGDSVSRETLRRLEQRQKMLEQELREHGQVVPKFKFPAFLEEQQEEQVDVRKRMKQPIG
EKRTKKQLDAEFETYFEEQMDGFREEHTIYYTHDGKPQVSGLAPLDKPEKMKMHEKVAAL
YTQALKLQAQLNPNETPTTWKSFKFPKNADKNLLESYLKLHGAGAQQDSEESEISSAEEE
ASDDENSGEEEPNTEKIEQNSCKAEASEQESNGGVRRRILVD
|
| References |
|
| Functional Descriptions |
K09E4.2
none available
|
| Deletion Mutants |
|
| In Situ |
|
| Expression |
Expression
|
WBGene00010720
Phenotype
Homology_paralog
|
|
|
| Phenotype |
Definition |
RNAi / Allele |
|
embryonic lethal
|
"Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die." [WB:cab, WB:WBPaper00000179, WB:WBPaper00004403, WB:WBPaper00004540, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00024497, WB:WBPaper00024925, WB:WBPaper00025054]
|
|
|
larval arrest
|
"The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage." [WB:WBPaper00002958, WB:WBPerson2021]
|
|
|
larval lethal
|
"The animal dies at any time between hatching and onset to adulthood." [GO:0002119, WB:WBPerson712]
|
|
|
lethal
|
"Animals die prematurely at any stage of the life cycle." [WB:WBPaper00001109, WB:WBPerson2021]
|
|
|
maternal sterile
|
" Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility)." [WB:cab, WB:cgc5599, WB:cgc7141, WB:WBPerson557]
|
|
|
organism morphology variant
|
"Animals exhibit variations in the form, structure or composition of any part of their anatomy compared to control animals." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00005654, WB:WBPaper00006395]
|
|
|
postembryonic development variant
|
"Any variation in the progression of an animal over time, from hatching to adulthood, compared to control." [WB:WBPerson2021]
|
|
|
protein aggregation variant
|
"Variations that result in the accumulation of soluble/insoluble protein aggregates in a particular cell or tissue, compared to control. Protein aggregates are often formed by interactions between misfolded protein molecules and/or deficiencies in proper protein folding." [WB:WBPaper00034765, WB:WBPerson2021]
|
|
|
slow growth
|
"Any variation that causes a reduction in growth rate compared to control." [WB:cab, WB:WBPaper00004402, WB:WBPaper00004403, WB:WBPaper00004651, WB:WBPaper00004769, WB:WBPaper00005654, WB:WBPaper00006395, WB:WBPaper00024497, WB:WBPerson557]
|
|
|
sterile progeny
|
"Any variation that compromises the reproductive ability of the progeny of an animal." [WB:WBPerson2021, WB:WBPerson557]
|
|
|
transgene subcellular localization variant
|
"Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals." [WB:WBPerson557]
|
|
|
Variant
|
"Animals exhibit variations compared to a given control." [WB:WBPerson557]
|
|